Stacks, checked
Each guide starts with a symptom or a trend you have probably seen online, explains what is going on with cited research, walks through the free fixes first, and ends with a short supplement stack: dose, timing, evidence grade and safety notes. Educational only, not medical advice.
Symptom guide · Sleep stackWaking at 3 a.m. in perimenopause: what is happening and what helps →You fall asleep fine, then you are wide awake at 3 a.m., hot or wired, mind already on tomorrow. Here is what is behind that pattern, the steps with the strongest evidence, and the small supplement stack we would try alongside them.Stack: Magnesium bisglycinate (glycinate) · L-theanine · Glycine · Standardized saffron extractSleepmaxxing, checked · Sleep stackThe sleep stack, minus the hype →Sleepmaxxing has 100 million TikTok posts and "magnesium for sleep" gets about 110,000 US searches a month. Here is what survives contact with the research, in the order we would add it, with doses.Stack: Magnesium bisglycinate (glycinate) · L-theanine · Glycine · Standardized saffron extractTrend explainer · Recovery stackThe Wolverine stack (BPC-157 + TB-500), explained honestly →Google searches for "wolverine stack" are up about twenty-fold in a year. Here is what the two peptides are, what the studies do and do not show, where they stand legally in October 2026, and what we would put in a recovery stack instead.Stack: Collagen or gelatin + vitamin C · Creatine monohydrate · Oral cartilage and collagen peptide bioregulators110,000 searches a month, answered · SleepMagnesium for sleep: glycinate vs threonate vs citrate →Magnesium is the most searched sleep supplement in the US, and the form on the label changes what you get. Here is which form fits which goal, the doses used in trials, and what each costs per month.Stack: Magnesium bisglycinate (glycinate) · Magnesium L-threonate (Magtein) · L-theaninePodcast protocol, checked · Sleep stackThe Huberman sleep stack, reviewed →Dr. Andrew Huberman’s sleep toolkit is the most copied supplement routine online. We graded each piece against the published human trials so you know which parts carry the weight and which are optional.Stack: Magnesium L-threonate (Magtein) · Magnesium bisglycinate (glycinate) · L-theanine · Glycine · ApigeninSearches up 62% this year · Strength & healthy agingCreatine for women over 40: what the trials actually show →“Creatine for women over 40” is one of the fastest-growing supplement searches. The short version: it works, modestly, when you take 5 g a day and lift. Here is the evidence, the dose and the honest caveats.Stack: Creatine monohydrate · Protein (food first) · All-in-one midlife bundle (creatine + collagen + vitamin D3 + turmeric + alpha-GPC)Longevity, checked · NAD+ stackNMN, NMNH and NAD+: what the human trials actually show →NAD+ falls with age, and NMN reliably raises it in people. Whether that slows aging is the open question. Here is what the randomized trials found, how NMN, NMNH and NR differ, the doses that were tested, and where we would spend the money.Stack: NMN (nicotinamide mononucleotide) · NMNH (reduced NMN)Functional mushrooms, checked · Focus stackLion’s Mane for focus and memory: what the trials show, and a mushroom stack →Lion’s Mane is the most searched functional mushroom, and most of what you read about it comes from mouse studies. Here is what the human trials actually found, how fruiting body and mycelium differ, the doses that were tested, and how we would build a simple mushroom stack around it.Stack: Lion’s Mane (Hericium erinaceus) fruiting-body extract · Lion’s Mane mycelium standardized to erinacine A · Cordyceps extract · Reishi (Ganoderma) fruiting-body extract · Five-mushroom beta-glucan blend (Reishi, Shiitake, Maitake, Turkey Tail, Chaga)
How we grade evidence: A = several randomized trials or a meta-analysis; B = at least one randomized trial or consistent small trials; C = small or pilot human data or mechanism only; D = animal or cell data, or anecdote. Written by the Kymata Health editorial team; medical review pending.