Health hubs
Evidence-first health hubs
Evidence-first health hubs: what the studies show, what the FDA and the courts have said about the brands, and where each option fits. Every page lists its sources and a last-verified date.
Women's health
- Menopause & PerimenopauseHormone therapy is still the most effective treatment for hot flashes, the FDA removed most of its boxed warning in 2026, two non-hormonal pills are now approved, and most menopause supplements have weak or null trials.
- Women's GLP-1 & WeightSemaglutide and tirzepatide produced 15% to 21% average weight loss in their main trials, and stopping led to regain. Compounded versions are not FDA-approved, and tirzepatide can make the pill less reliable.
For everyone
- Sleep & MagnesiumCognitive behavioral therapy is the first-line treatment for chronic insomnia. Magnesium has small, low-quality trials with modest effects, melatonin shortens sleep onset by about 7 minutes, gummy labels are often wrong, and tart cherry rests on three pilot studies.
- Metabolic Health & Blood SugarLifestyle change cut new diabetes by 58% in the landmark prevention trial, more than metformin. Over-the-counter glucose monitors are now FDA-cleared, but their benefit for people without diabetes is unproven, and most blood sugar supplements were tested in people who already had diabetes.