Evidence explainerSleep & Magnesium
Tart Cherry Juice for Sleep: Three Pilot Studies and What They Show
Tart cherry juice has been tested for sleep in three small crossover studies with 8 to 20 completers each. Results were mixed and the effects were modest.
Key takeaways
- In 15 older adults with chronic insomnia, a tart cherry juice blend reduced wake time after sleep onset vs placebo but did not improve sleep onset, total sleep or efficiency [1].
- In a polysomnography study, 8 completers over 50 with insomnia slept 84 minutes longer on tart cherry juice (240 mL twice a day) [2].
- In 20 healthy adults, tart cherry concentrate for 7 days raised urinary melatonin and increased total sleep time and efficiency on actigraphy [3].
- These are pilot-scale studies; the 2010 authors called the effects modest and far smaller than CBT-I or hypnotics [1].
The three studies
Pigeon 2010: a randomized, double-blind crossover in 15 older adults with insomnia, 2 weeks each of a tart cherry juice blend and placebo [1]. Only wake after sleep onset improved vs placebo; effect sizes were moderate to negligible [1].
Losso 2018: 11 people over 50 were randomized; 3 with sleep apnea were excluded, leaving 8 completers who slept 84 minutes longer on polysomnography during 2 weeks of juice [2]. Howatson 2012: 20 healthy volunteers took concentrate or placebo for 7 days and showed higher urinary melatonin plus more total sleep time and sleep efficiency [3].
Proposed mechanisms
Tart Montmorency cherries contain melatonin, and one study found higher urinary melatonin after the concentrate [3]. Another proposed that cherry procyanidin B-2 raises tryptophan availability by inhibiting the IDO enzyme, based on blood markers and cell experiments [2].
Bottom line
Tart cherry juice is a food with a plausible mechanism and small positive pilot studies, not a proven insomnia treatment [1]. It also adds sugar and calories to an evening routine. For chronic insomnia the first-line treatment is CBT-I [4]; for supplements with more trials, see our magnesium for sleep guide.
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References
- [1]Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. J Med Food, 2010.
- [2]Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. Am J Ther, 2018.
- [3]Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. Eur J Nutr, 2012.
- [4]Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med, 2016.
