What the evidence buys you, per month
Each dot is a product, priced per month at the dose the trials used, on the grade of the strongest evidence for that supplement. Pick a goal, then tap two dots to compare.
Evidence per Dollar · Kymata Health Prices checked Oct 8 to 20, 2026 By Kymata Health Editorial No paid links on this page How it works
Evidence grade against monthly cost
72 products · 29 supplementsSame ingredient, same dose
$82.80 more a month for the same 5 g a day. The evidence is the same row for both.
Top pick: Magnesium glycinate, blood pressure
Where to buy Magnesium glycinateShelves
- Best value · Sleep$0.76/moBotanic Choice · MelatoninBGrade BEarlier sleep onset with a delayed body clock. 0.5 mg a day.Open the evidence
- Best value · Brain & focus$20.27/moMomentous · L-theanineBGrade BAttention (choice reaction time) and acute stress. 200 mg a day.Open the evidence
- Best value · Stress$3.29/moHerbsPro · OrnithineDGrade DStress hormones, mood and perceived sleep quality. 400 mg a day.Open the evidence
- Best value · Healthy aging$4.10/moMicro Ingredients · Creatine monohydrateBGrade BLean mass and strength in postmenopausal women. 5 g a day.Open the evidence
- No effect in trials$7.15/moHerbsPro · Magnesium malate∅No effectNo effect on fibromyalgia pain and tenderness. 300 mg a day.What it would cost, not a buy path
Ranked: grade first, then the top-spot price
29 supplements- 1Magnesium glycinateBlood pressure. 300 mg a day; trial form: various oral forms.AGrade A$9.12$9.12 to $39.54, 11 products
- 2Vitamin C (ascorbic acid vs buffered vs liposomal)Chance of catching a cold under heavy physical stress. 200 mg a day; trial form: vitamin C (regular daily intake).BGrade B$0.68$0.68 to $9.73, 3 products
- 3MelatoninEarlier sleep onset with a delayed body clock. 0.5 mg a day.BGrade B$0.76$0.76 to $5.06, 5 products
- 4Creatine monohydrateLean mass and strength in postmenopausal women. 5 g a day.BGrade B$4.10$4.10 to $86.90, 18 products
- 5Soy isoflavonesHot flash frequency. 54 mg a day.Also graded C as a harm: endometrial hyperplasia (safety).BGrade B$5.701 product
- 6L-theanineAttention (choice reaction time) and acute stress. 200 mg a day; trial form: l-theanine (oral).BGrade B$20.27$20.27 to $20.28, 2 products
- 7InositolRegular menstrual periods in PCOS. 4,000 mg a day; trial form: myo-inositol, D-chiro-inositol or both.BGrade B$67.571 product
- 8Riboflavin (Vitamin B2)Blood pressure in medicated hypertension with the MTHFR 677TT genotype. 1.6 mg a day.CGrade C$0.031 product
- 9Devil's ClawPain-free days during a flare of chronic low back pain. 1,200 mg a day.CGrade C$9.501 product
- 10BromelainPain, swelling and quality of life after wisdom tooth removal. 1,000 mg a day.CGrade C$10.81$10.81 to $13.94, 2 products
- 11White Kidney Bean ExtractWeight and fat loss during calorie restriction (Phase 2 extract). 3,000 mg a day.CGrade C$15.151 product
- 12Artichoke ExtractFunctional dyspepsia symptoms and quality of life. 1,920 mg a day.CGrade C$17.691 product
- 13Stinging NettleProstate urinary symptoms (IPSS) over 12 months. 459 mg a day.CGrade CNo top spot1 product
- 14Glutathione (oral)Skin melanin index. 500 mg a day.CGrade CNo top spot1 product
- 15Urolithin AMuscle strength and endurance in middle-aged adults. 500 mg a day.CGrade CNo top spot1 product
- 16Bovine colostrumSelf-reported upper respiratory symptoms. 60 g a day.Also graded C as a harm: intestinal permeability during running training.CGrade CNo top spot$1,581.67 to $1,736.79, 2 products
- 17OrnithineStress hormones, mood and perceived sleep quality. 400 mg a day.DGrade D$3.291 product
- 18RutinBlood sugar, insulin resistance and lipids in type 2 diabetes. 500 mg a day.DGrade D$3.771 product
- 19Magnesium taurateBlood pressure in adults with elevated BP. 121 mg a day; trial form: magnesium taurate with potassium citrate, plus lifestyle counselling.DGrade D$4.541 product
- 20ElderberryCold duration and severity. 900 mg a day.DGrade D$8.141 product
- 21NattokinaseBlood pressure in a North American hypertensive population. 100 mg a day.DGrade D$8.491 product
- 22LysineRecurrent herpes simplex: outbreaks, severity and time to clear. 3,000 mg a day.DGrade D$10.17$10.17 to $27.38, 3 products
- 23Pantothenic Acid (Vitamin B5)Facial acne lesion count. 2,200 mg a day; trial form: pantothenic acid-based dietary supplement (Pantothen tablets).DGrade D$10.451 product
- 24L-HistidineInsulin resistance (HOMA-IR), body fat and inflammatory markers. 4,000 mg a day.DGrade D$52.791 product
- 25Bitter melonFasting glucose and insulin resistance in prediabetes (freeze-dried fruit). 3,600 mg a day.DGrade D$63.841 product
- 26Activated CharcoalTotal and LDL cholesterol vs cholestyramine and bran. 16,000 mg a day.DGrade D$119.411 product
- 27Cannabidiol (CBD)Anxiety during a simulated public speaking test in social anxiety disorder. 600 mg a day.Also graded B as a harm: pain intensity in fibromyalgia.DGrade D$231.17$231.17 to $1,216.42, 2 products
- 28Sea BuckthornVaginal dryness and tissue health after menopause. 3,000 mg a day.DGrade DNo top spot1 product
- 29Magnesium malateNo effect: fibromyalgia pain and tenderness. 300 mg a day; trial form: tablet of magnesium 50 mg with malic acid 200 mg.∅No effect$7.15$7.15 to $24.87, 5 products
Every product we priced
29 supplements and 72 products, each at its best-supported outcome. Open a row for its products: price, servings, the amount per serving and the date each was read.
- Lowest monthly cost
- Lowest with a third-party certification
- Other products
1Magnesium glycinate
AGrade ABlood pressure
Meta-analysis of 34 studies, 2,028 people, 2016. PMID 27402922 (opens in new tab)
Tested form: various oral forms, not magnesium glycinate alone. The prices are for magnesium glycinate products only.
From
$9.12 a month
at 300 mg a day · Doctor's Best High Absorption Magnesium (lysinate glycinate chelate)
Up to $39.54 a month for the most expensive of 11.
Lowest with a third-party certification: Nature Made High Absorption Magnesium Glycinate 200 mg (USP Verified), $16.22 a month.
Studied dose: 300 mg/day: amount the blood-pressure meta-analysis linked to an effect. Prices checked Oct 10 to 19, 2026.
All 11 products, cheapest first
Magnesium glycinate: every product we priced, per month at 300 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Doctor's Best High Absorption Magnesium (lysinate glycinate chelate) · glycinate $9.12 200 mg2 tablets 1.5 $23.99, 120 No certification named Oct 10, 2026 on doctorsbest.com HerbsPro NOW Foods Magnesium Glycinate, 90 Tabs $11.40 200 mg2 per serving 1.5 $11.24, 45 No certification named Oct 14, 2026 on herbspro.com Dr. Tobias Dr. Tobias Magnesium Bisglycinate (120 capsules) $11.40 200 mg1 per serving 1.5 $29.99, 120 No certification named Oct 14, 2026 on drtobias.com Toplux Magnesium Glycinate · glycinate $11.57 525 mg3 capsules 0.57 $19.97, 30one-time (Amazon; list $29.97) No certification named Oct 10, 2026 on amazon.com NOW Foods Magnesium Glycinate tablets · glycinate $12.16 200 mg2 tablets 1.5 $23.99, 90one-time (sale, regular $31.99) No certification named Oct 10, 2026 on nowfoods.com Nature Made High Absorption Magnesium Glycinate 200 mg · glycinate $16.22 200 mg2 capsules 1.5 $31.99, 90one-time (Amazon) USP Verified Oct 10, 2026 on amazon.com Pure Encapsulations Magnesium (glycinate) · glycinate $19.64 120 mg1 capsule 2.5 $46.50, 180 No certification named Oct 10, 2026 on pureforyou.com Klean Athlete Klean Magnesium · glycinate $22.39 120 mg1 capsule 2.5 $26.50, 90 No certification named Oct 10, 2026 on kleanathlete.com Botanic Choice Botanic Choice Magnesium Glycinate, 240 mg, 60 capsules $25.35 240 mg2 per serving 1.25 $20.00, 30 No certification named Oct 19, 2026 on botanicchoice.com Momentous Momentous Magnesium Bisglycinate, 60 capsules $25.84 200 mg2 per serving 1.5 $16.99, 30 No certification named Oct 15, 2026 on livemomentous.com Supersmart Magnesium Bisglycinate (Albion TRAACS) $39.54 300 mg4 per serving 1 $39.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts magnesium per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
2Vitamin C (ascorbic acid vs buffered vs liposomal)
BGrade BChance of catching a cold under heavy physical stress
Meta-analysis, 598 people, 2013. PMID 23440782 (opens in new tab)
Tested form: vitamin C (regular daily intake), not vitamin c (ascorbic acid vs buffered vs liposomal) alone. The prices are for vitamin c (ascorbic acid vs buffered vs liposomal) products only.
From
$0.68 a month
at 200 mg a day · HerbsPro NOW Foods Vitamin C-500, 100 Tabs
Up to $9.73 a month for the most expensive of 3.
Studied dose: 200 mg/day: lowest daily dose in the Cochrane cold trials. Prices checked Oct 11 to 15, 2026.
All 3 products, cheapest first
Vitamin C (ascorbic acid vs buffered vs liposomal): every product we priced, per month at 200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Vitamin C-500, 100 Tabs $0.68 500 mg1 per serving 0.4 $5.62, 100 No certification named Oct 14, 2026 on herbspro.com Renue by Science Renue by Science LIPO Vitamin C, liposomal capsules (120) $3.54 1,000 mg2 per serving 0.2 $34.95, 60 No certification named Oct 15, 2026 on renuebyscience.com Supersmart Liposomal Vitamin C (Quali-C) $9.73 1,000 mg3 per serving 0.2 $48.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts vitamin C per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
3Melatonin
BGrade BEarlier sleep onset with a delayed body clock
RCT, 116 people, 2018. PMID 29912983 (opens in new tab)
From
$0.76 a month
at 0.5 mg a day · Botanic Choice Botanic Choice Melatonin 3 mg Dual Release, 60 vege capsules
Up to $5.06 a month for the most expensive of 5.
Studied dose: 0.5 mg: nightly dose in the delayed sleep-timing trial. Prices checked Oct 11 to 19, 2026.
All 5 products, cheapest first
Melatonin: every product we priced, per month at 0.5 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Botanic Choice Botanic Choice Melatonin 3 mg Dual Release, 60 vege capsules $0.76 3 mg1 per serving 0.17 $9.00, 60 No certification named Oct 19, 2026 on botanicchoice.com Botanic Choice Botanic Choice Melatonin 1 mg, 120 tablets $0.89 1 mg1 per serving 0.5 $7.00, 120 No certification named Oct 19, 2026 on botanicchoice.com HerbsPro Natrol Melatonin Fast Dissolve, Strawberry, 1 mg, 90 Tabs $1.28 1 mg1 per serving 0.5 $7.60, 90 No certification named Oct 19, 2026 on herbspro.com Supersmart Melatonin Supplement (1 mg tablets) $1.77 1 mg1 per serving 0.5 $14.00, 120 No certification named Oct 11, 2026 on us.supersmart.com Renue by Science Renue by Science LIPO Melatonin, liposomal capsules (90) $5.06 1 mg1 per serving 0.5 $29.95, 90 No certification named Oct 15, 2026 on renuebyscience.com Amount per serving counts melatonin per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
4Creatine monohydrate
BGrade BLean mass and strength in postmenopausal women
Meta-analysis, 608 people, 2026. PMID 42141930 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade A, muscular power and strength across lifts; grade A, lean body mass; grade A, muscle strength with resistance training.
From
$4.10 a month
at 5 g a day · Micro Ingredients Creatine Monohydrate powder
Up to $86.90 a month for the most expensive of 18.
Lowest with a third-party certification: Naked Nutrition Naked Creatine (NSF Contents Certified), $5.47 a month.
Studied dose: 5 g/day: amount linked to gains in postmenopausal women who trained. Prices checked Oct 8 to 20, 2026.
All 18 products, cheapest first
Creatine monohydrate: every product we priced, per month at 5 g a day Product Per month Per serving Servings a day Price, servings Certification Checked Micro Ingredients Creatine Monohydrate powder · powder $4.10 5 g 1 $26.99, 200one-time (Amazon; list $29.95) No certification named Oct 10, 2026 on amazon.com BulkSupplements Creatine Monohydrate · powder $4.56 5 g 1 $29.97, 200 No certification named Oct 10, 2026 on bulksupplements.com Naked Nutrition Naked Creatine · powder $5.47 5 g 1 $35.99, 200 NSF Contents Certified Oct 10, 2026 on nakednutrition.com Nutricost Creatine Monohydrate powder · powder $7.29 5 g 1 $23.97, 100 No certification named Oct 10, 2026 on nutricost.com Kaged Creatine Monohydrate · powder $7.60 5 g1 scoop (5.1 g) 1 $24.99, 100 Informed Sport Oct 10, 2026 on kaged.com NOW Sports Creatine Monohydrate powder · powder $8.10 5 g1.5 tsp (about 5 g) 1 $11.99, 45one-time (sale, regular $15.99) Informed Sport Oct 10, 2026 on nowfoods.com Optimum Nutrition Micronized Creatine Monohydrate powder · powder $8.11 5 g 1 $31.99, 120 No certification named Oct 10, 2026 on optimumnutrition.com Onnit Onnit Creatine, unflavored (90-serving tub) $12.84 5 gone serving 1 $37.99, 90 No certification named Oct 20, 2026 on onnit.com Dr. Tobias Dr. Tobias Creatine Monohydrate (90 tablets) $13.72 4.8 g3 per serving 1.04 $12.99, 30 No certification named Oct 14, 2026 on drtobias.com Momentous Momentous Creatine, 90 servings $14.53 5 gone serving 1 $42.99, 90 No certification named Oct 15, 2026 on livemomentous.com Thorne Creatine · powder $14.87 5 g1 scoop 1 $44.00, 90 NSF Certified for Sport Oct 10, 2026 on thorne.com ProHealth Longevity Creatine Pure Powder $16.88 5 g1 scoop (5 g) 1 $49.95, 90 No certification named Oct 8, 2026 on prohealth.com Klean Athlete Klean Creatine · powder $17.49 5 g1 scoop (about 5 g) 1 $34.50, 60 No certification named Oct 10, 2026 on kleanathlete.com Supersmart 3-Creatine $21.00 3 gone serving 1.67 $29.00, 70 No certification named Oct 11, 2026 on us.supersmart.com Legion Creatine Gummies · gummy $40.55 5 g4 gummies 1 $39.99, 30 No certification named Oct 10, 2026 on legionathletics.com Momentous Momentous Creatine Chews, 150 count $50.68 1 g1 per serving 5 $49.99, 150 No certification named Oct 19, 2026 on livemomentous.com Create Wellness Creatine Monohydrate Gummies · gummy $75.48 4.5 g3 gummies 1.11 $201.00, 90one-time (struck $218) NSF Certified for Sport Oct 10, 2026 on trycreate.co Bear Balanced Creatine Gummies · gummy $86.90 3.5 g3 gummies 1.43 $60.00, 30 Informed Sport Oct 10, 2026 on creatinegummies.com Amount per serving counts creatine monohydrate per serving (g, from Supplement Facts). Prices are one-time, before tax and shipping.
5Soy isoflavones
BGrade BHot flash frequency
Meta-analysis of 13 studies, 1,196 people, 2012. PMID 22433977 (opens in new tab)
Also graded C, as a harm: endometrial hyperplasia (safety) went up (PMID 15237003 (opens in new tab)).
From
$5.70 a month
at 54 mg a day · HerbsPro NOW Foods Soy Isoflavones, 60 mg, 120 Veg Caps
Studied dose: 54 mg/day: median dose in the hot flash meta-analysis. Prices checked Oct 14, 2026.
The one product we priced
Soy isoflavones: every product we priced, per month at 54 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Soy Isoflavones, 60 mg, 120 Veg Caps $5.70 60 mg1 per serving 0.9 $24.98, 120 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts total isoflavones per serving (mg). Prices are one-time, before tax and shipping.
6L-theanine
BGrade BAttention (choice reaction time) and acute stress
Meta-analysis, 1,168 people, 2026. PMID 42410082 (opens in new tab)
Tested form: l-theanine (oral), not l-theanine alone. The prices are for l-theanine products only.
From
$20.27 a month
at 200 mg a day · Momentous Momentous L-Theanine, 60 capsules
Up to $20.28 a month for the most expensive of 2.
Studied dose: 200 mg: single dose in the attention trials. Prices checked Oct 11 to 15, 2026.
All 2 products, cheapest first
L-theanine: every product we priced, per month at 200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Momentous Momentous L-Theanine, 60 capsules $20.27 200 mg1 per serving 1 $39.99, 60 No certification named Oct 15, 2026 on livemomentous.com Supersmart L-Theanine $20.28 400 mg4 per serving 0.5 $20.00, 15 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts l-theanine per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
7Inositol
BGrade BRegular menstrual periods in PCOS
Meta-analysis of 26 studies, 1,691 people, 2023. PMID 36703143 (opens in new tab)
Tested form: myo-inositol, D-chiro-inositol or both, not inositol alone. The prices are for inositol products only.
From
$67.57 a month
at 4,000 mg a day · Momentous Momentous Inositol, 120 capsules
Studied dose: 4,000 mg/day: most common PCOS trial dose and the pregnancy trial dose. Prices checked Oct 15, 2026.
The one product we priced
Inositol: every product we priced, per month at 4,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Momentous Momentous Inositol, 120 capsules $67.57 900 mg2 per serving 4.44 $29.99, 60 No certification named Oct 15, 2026 on livemomentous.com Amount per serving counts myo-inositol per serving (mg). Prices are one-time, before tax and shipping.
8Riboflavin (Vitamin B2)
CGrade CBlood pressure in medicated hypertension with the MTHFR 677TT genotype
RCT, 91 people, 2013. PMID 23608654 (opens in new tab)
From
$0.03 a month
at 1.6 mg a day · HerbsPro NOW Foods Vitamin B-2, 100 mg, 100 Veg Caps
Studied dose: 1.6 mg/day: blood pressure trials. Prices checked Oct 15, 2026.
The one product we priced
Riboflavin (Vitamin B2): every product we priced, per month at 1.6 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Vitamin B-2, 100 mg, 100 Veg Caps $0.03 100 mg1 per serving 0.02 $6.23, 100 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts riboflavin per serving (mg). Prices are one-time, before tax and shipping.
9Devil's Claw
CGrade CPain-free days during a flare of chronic low back pain
RCT, 197 people, 1999. PMID 10101629 (opens in new tab)
From
$9.50 a month
at 1,200 mg a day · HerbsPro Nature's Way Devil's Claw Root, 100 Caps
Studied dose: 1,200 mg/day: WS 1531 extract (100 mg harpagoside) in the back pain trial. Prices checked Oct 15, 2026.
The one product we priced
Devil's Claw: every product we priced, per month at 1,200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Nature's Way Devil's Claw Root, 100 Caps $9.50 960 mg2 per serving 1.25 $12.49, 50 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts devil's claw per serving (mg). Prices are one-time, before tax and shipping.
10Bromelain
CGrade CPain, swelling and quality of life after wisdom tooth removal
RCT, 45 people, 2014. PMID 24589242 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade B, need for surgical excision in deep burns (prescription topical bromelain).
From
$10.81 a month
at 1,000 mg a day · Botanic Choice Botanic Choice Bromelain, 500 mg, 90 capsules
Up to $13.94 a month for the most expensive of 2.
Studied dose: 1,000 mg/day: wisdom tooth surgery trial. Prices checked Oct 12 to 14, 2026.
All 2 products, cheapest first
Bromelain: every product we priced, per month at 1,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Botanic Choice Botanic Choice Bromelain, 500 mg, 90 capsules $10.81 500 mg1 per serving 2 $16.00, 90 No certification named Oct 12, 2026 on botanicchoice.com HerbsPro NOW Foods Bromelain, 500 mg, 120 Veg Caps $13.94 500 mg1 per serving 2 $27.49, 120 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts bromelain per serving (mg). Prices are one-time, before tax and shipping.
11White Kidney Bean Extract
CGrade CWeight and fat loss during calorie restriction (Phase 2 extract)
RCT, 81 people, 2024. PMID 38830962 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade B, body weight and fat mass in overweight and obesity.
From
$15.15 a month
at 3,000 mg a day · HerbsPro Nutricost White Kidney Bean Capsules, 120 Count
Studied dose: 3,000 mg/day: higher Phase 2 and Phaseolean dose. Prices checked Oct 15, 2026.
The one product we priced
White Kidney Bean Extract: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Nutricost White Kidney Bean Capsules, 120 Count $15.15 650 mg1 per serving 4.62 $12.95, 120 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts white kidney bean extract per serving (mg). Prices are one-time, before tax and shipping.
12Artichoke Extract
CGrade CFunctional dyspepsia symptoms and quality of life
RCT, 247 people, 2003. PMID 14653829 (opens in new tab)
From
$17.69 a month
at 1,920 mg a day · HerbsPro NOW Foods Artichoke Extract, 450 mg, 90 Vcaps
Studied dose: 1,920 mg/day: dose in the functional dyspepsia trial. Prices checked Oct 14, 2026.
The one product we priced
Artichoke Extract: every product we priced, per month at 1,920 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Artichoke Extract, 450 mg, 90 Vcaps $17.69 450 mg1 per serving 4.27 $12.27, 90 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts artichoke leaf extract per serving (mg). Prices are one-time, before tax and shipping.
13Stinging Nettle
CGrade CProstate urinary symptoms (IPSS) over 12 months
RCT, 246 people, 2004. PMID 15045190 (opens in new tab)
From
$6.83 a month
at 459 mg a day · Supersmart Nettle Root Extract
Studied dose: 459 mg/day: dose in the 12-month prostate trial. Prices checked Oct 11, 2026.
The one product we priced
Stinging Nettle: every product we priced, per month at 459 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Nettle Root Extract $6.83 1,500 mg3 per serving 0.31 $22.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts nettle root extract per serving (mg). Prices are one-time, before tax and shipping.
14Glutathione (oral)
CGrade CSkin melanin index
RCT, 60 people, 2012. PMID 20524875 (opens in new tab)
From
$67.53 a month
at 500 mg a day · Renue by Science Renue by Science LIPO Glutathione, liposomal capsules (90)
Studied dose: 500 mg/day: dose in the 4-week skin-lightening trial. Prices checked Oct 15, 2026.
The one product we priced
Glutathione (oral): every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Renue by Science Renue by Science LIPO Glutathione, liposomal capsules (90) $67.53 130 mg1 per serving 3.85 $51.95, 90 No certification named Oct 15, 2026 on renuebyscience.com Amount per serving counts glutathione per serving (mg). Prices are one-time, before tax and shipping.
15Urolithin A
CGrade CMuscle strength and endurance in middle-aged adults
RCT, 88 people, 2022. PMID 35584623 (opens in new tab)
From
$108.49 a month
at 500 mg a day · Supersmart Urolithin A
Studied dose: 500 mg/day: low dose in the middle-aged trial. Prices checked Oct 12, 2026.
The one product we priced
Urolithin A: every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Urolithin A $108.49 500 mg2 per serving 1 $107.00, 30 No certification named Oct 12, 2026 on us.supersmart.com Amount per serving counts urolithin A per serving (mg). Prices are one-time, before tax and shipping.
16Bovine colostrum
CGrade CSelf-reported upper respiratory symptoms
RCT, 174 people, 2003. PMID 12923655 (opens in new tab)
Also graded C, as a harm: intestinal permeability during running training went up (PMID 22253980 (opens in new tab)).
From
$1,581.67 a month
at 60 g a day · Supersmart Colostrum
Up to $1,736.79 a month for the most expensive of 2.
Studied dose: 60 g/day: dose in the respiratory symptom and running trials. Prices checked Oct 11 to 20, 2026.
All 2 products, cheapest first
Bovine colostrum: every product we priced, per month at 60 g a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Colostrum $1,581.67 1 g2 per serving 60 $26.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Physician’s Choice Physician’s Choice Colostrum Gold Powder, unflavored (30 servings) $1,736.79 2 gone serving 30 $57.10, 30 No certification named Oct 20, 2026 on physicianschoice.com Amount per serving counts bovine colostrum per serving (g). Prices are one-time, before tax and shipping.
17Ornithine
DGrade DStress hormones, mood and perceived sleep quality
RCT, 52 people, 2014. PMID 24889392 (opens in new tab)
From
$3.29 a month
at 400 mg a day · HerbsPro NOW Foods L-Ornithine, 500 mg, 120 Caps
Studied dose: 400 mg/day: 8-week stress and sleep trial. Prices checked Oct 14, 2026.
The one product we priced
Ornithine: every product we priced, per month at 400 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Ornithine, 500 mg, 120 Caps $3.29 1,500 mg3 per serving 0.27 $16.23, 40 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts l-ornithine per serving (mg). Prices are one-time, before tax and shipping.
18Rutin
DGrade DBlood sugar, insulin resistance and lipids in type 2 diabetes
RCT, 50 people, 2023. PMID 36101997 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, leg swelling in chronic venous insufficiency (phlebotonic drugs, including rutosides).
From
$3.77 a month
at 500 mg a day · HerbsPro NOW Foods Rutin, 450 mg, 100 Vcaps
Studied dose: 500 mg/day: dose in both plain-rutin trials. Prices checked Oct 14, 2026.
The one product we priced
Rutin: every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Rutin, 450 mg, 100 Vcaps $3.77 450 mg1 per serving 1.11 $11.16, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts rutin per serving (mg). Prices are one-time, before tax and shipping.
19Magnesium taurate
DGrade DBlood pressure in adults with elevated BP
Observational, 121 people, 2026. PMID 42439043 (opens in new tab)
Tested form: magnesium taurate with potassium citrate, plus lifestyle counselling, not magnesium taurate alone. The prices are for magnesium taurate products only.
From
$4.54 a month
at 121 mg a day · Life Extension Magnesium Taurate
Studied dose: 121 mg/day: magnesium in the single-arm blood pressure study. Prices checked Oct 10, 2026.
The one product we priced
Magnesium taurate: every product we priced, per month at 121 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Life Extension Magnesium Taurate · taurate $4.54 125 mg1 capsule 0.97 $27.75, 180 No certification named Oct 10, 2026 on lifeextension.com Amount per serving counts elemental mg of magnesium per serving, as printed on the label. Prices are one-time, before tax and shipping.
20Elderberry
DGrade DCold duration and severity
RCT, 312 people, 2016. PMID 27023596 (opens in new tab)
From
$8.14 a month
at 900 mg a day · HerbsPro NOW Foods Elderberry, 500 mg, 60 Veg Caps
Studied dose: 900 mg/day: travel-phase dose in the air-travel cold trial. Prices checked Oct 14, 2026.
The one product we priced
Elderberry: every product we priced, per month at 900 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Elderberry, 500 mg, 60 Veg Caps $8.14 500 mg1 per serving 1.8 $8.92, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts elderberry extract per serving (mg). Prices are one-time, before tax and shipping.
21Nattokinase
DGrade DBlood pressure in a North American hypertensive population
RCT, 79 people, 2016. PMID 27785095 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, blood pressure in prehypertension or stage 1 hypertension.
From
$8.49 a month
at 100 mg a day · HerbsPro NOW Foods Nattokinase, 100 mg, 60 Vcaps
Studied dose: 100 mg/day: dose in the North American blood-pressure trial. Prices checked Oct 14, 2026.
The one product we priced
Nattokinase: every product we priced, per month at 100 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Nattokinase, 100 mg, 60 Vcaps $8.49 100 mg1 per serving 1 $16.74, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts nattokinase per serving (mg). Prices are one-time, before tax and shipping.
22Lysine
DGrade DRecurrent herpes simplex: outbreaks, severity and time to clear
RCT, 52 people, 1987. PMID 3115841 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, diarrhea and respiratory illness days.
From
$10.17 a month
at 3,000 mg a day · HerbsPro NOW Foods L-Lysine, 500 mg, 100 Tabs
Up to $27.38 a month for the most expensive of 3.
Studied dose: 3,000 mg/day: dose in the 1987 six-month trial. Prices checked Oct 11 to 14, 2026.
All 3 products, cheapest first
Lysine: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Lysine, 500 mg, 100 Tabs $10.17 500 mg1 per serving 6 $5.57, 100 No certification named Oct 14, 2026 on herbspro.com Dr. Tobias Dr. Tobias L-Lysine 500 mg (100 tablets) $18.23 500 mg1 per serving 6 $9.99, 100 No certification named Oct 14, 2026 on drtobias.com Supersmart L-Lysine $27.38 3,000 mg6 per serving 1 $27.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts l-lysine per serving (mg). Prices are one-time, before tax and shipping.
23Pantothenic Acid (Vitamin B5)
DGrade DFacial acne lesion count
RCT, 41 people, 2014. PMID 24831048 (opens in new tab)
Tested form: pantothenic acid-based dietary supplement (Pantothen tablets), not pantothenic acid (vitamin b5) alone. The prices are for pantothenic acid (vitamin b5) products only.
From
$10.45 a month
at 2,200 mg a day · HerbsPro NOW Foods Pantothenic Acid, 500 mg, 100 Caps
Studied dose: 2,200 mg/day: acne trial. Prices checked Oct 14, 2026.
The one product we priced
Pantothenic Acid (Vitamin B5): every product we priced, per month at 2,200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Pantothenic Acid, 500 mg, 100 Caps $10.45 500 mg1 per serving 4.4 $7.81, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts pantothenic acid per serving (mg). Prices are one-time, before tax and shipping.
24L-Histidine
DGrade DInsulin resistance (HOMA-IR), body fat and inflammatory markers
RCT, 92 people, 2013. PMID 23361591 (opens in new tab)
From
$52.79 a month
at 4,000 mg a day · HerbsPro NOW Foods L-Histidine, 600 mg, 60 VegCaps
Studied dose: 4,000 mg/day: dose in the eczema and insulin-resistance trials. Prices checked Oct 14, 2026.
The one product we priced
L-Histidine: every product we priced, per month at 4,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Histidine, 600 mg, 60 VegCaps $52.79 600 mg1 per serving 6.67 $15.62, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts l-histidine per serving (mg). Prices are one-time, before tax and shipping.
25Bitter melon
DGrade DFasting glucose and insulin resistance in prediabetes (freeze-dried fruit)
RCT, 38 people, 2025. PMID 40199408 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade C, fasting glucose and HbA1c in type 2 diabetes (pooled trials); grade C, total cholesterol and triglycerides (pooled RCTs).
From
$63.84 a month
at 3,600 mg a day · HerbsPro Solaray Bitter Melon Fruit Extract, 500 mg, 60 Caps
Studied dose: 3,600 mg/day: 12-week prediabetes trial. Prices checked Oct 15, 2026.
The one product we priced
Bitter melon: every product we priced, per month at 3,600 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Solaray Bitter Melon Fruit Extract, 500 mg, 60 Caps $63.84 500 mg1 per serving 7.2 $17.49, 60 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts bitter melon (dried fruit or extract) per serving (mg). Prices are one-time, before tax and shipping.
26Activated Charcoal
DGrade DTotal and LDL cholesterol vs cholestyramine and bran
Crossover RCT, 10 people, 1989. PMID 2612535 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade C, functional dyspepsia symptoms (charcoal, simethicone and magnesium oxide); grade C, dyspepsia symptoms (charcoal plus simethicone).
From
$119.41 a month
at 16,000 mg a day · HerbsPro NOW Foods Activated Charcoal, 200 Veg Caps
Studied dose: 16,000 mg/day: cholesterol crossover study. Prices checked Oct 14, 2026.
The one product we priced
Activated Charcoal: every product we priced, per month at 16,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Activated Charcoal, 200 Veg Caps $119.41 560 mg2 per serving 28.57 $13.74, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts activated charcoal per serving (mg). Prices are one-time, before tax and shipping.
27Cannabidiol (CBD)
DGrade DAnxiety during a simulated public speaking test in social anxiety disorder
RCT, 24 people, 2011. PMID 21307846 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade A, seizure frequency in treatment-resistant epilepsy (prescription CBD); grade C, anxiety symptoms across anxiety disorders.
Also graded B, as a harm: pain intensity in fibromyalgia went up (PMID 40846590 (opens in new tab)).
From
$231.17 a month
at 600 mg a day · Neurogan Neurogan CBD Softgels Extra Strength (60 count)
Up to $1,216.42 a month for the most expensive of 2.
Studied dose: 600 mg: social anxiety trial single dose. Prices checked Oct 16, 2026.
All 2 products, cheapest first
Cannabidiol (CBD): every product we priced, per month at 600 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Neurogan Neurogan CBD Softgels Extra Strength (60 count) $231.17 125 mg1 per serving 4.8 $95.00, 60 No certification named Oct 16, 2026 on neurogan.com Green Roads Green Roads CBD Softgels 25mg (30 count) $1,216.42 25 mg1 per serving 24 $49.99, 30 No certification named Oct 16, 2026 on greenroads.com Amount per serving counts cBD per serving (mg). Prices are one-time, before tax and shipping.
28Sea Buckthorn
DGrade DVaginal dryness and tissue health after menopause
RCT, 116 people, 2014. PMID 25104582 (opens in new tab)
From
$106.46 a month
at 3,000 mg a day · Supersmart Sea Buckthorn Extract Supplement
Studied dose: 3,000 mg/day: vaginal dryness trial. Prices checked Oct 11, 2026.
The one product we priced
Sea Buckthorn: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Sea Buckthorn Extract Supplement $106.46 1,000 mg2 per serving 3 $35.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts sea buckthorn oil per serving (mg). Prices are one-time, before tax and shipping.
1Riboflavin (Vitamin B2)
CGrade CBlood pressure in medicated hypertension with the MTHFR 677TT genotype
RCT, 91 people, 2013. PMID 23608654 (opens in new tab)
From
$0.03 a month
at 1.6 mg a day · HerbsPro NOW Foods Vitamin B-2, 100 mg, 100 Veg Caps
Studied dose: 1.6 mg/day: blood pressure trials. Prices checked Oct 15, 2026.
The one product we priced
Riboflavin (Vitamin B2): every product we priced, per month at 1.6 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Vitamin B-2, 100 mg, 100 Veg Caps $0.03 100 mg1 per serving 0.02 $6.23, 100 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts riboflavin per serving (mg). Prices are one-time, before tax and shipping.
2Vitamin C (ascorbic acid vs buffered vs liposomal)
BGrade BChance of catching a cold under heavy physical stress
Meta-analysis, 598 people, 2013. PMID 23440782 (opens in new tab)
Tested form: vitamin C (regular daily intake), not vitamin c (ascorbic acid vs buffered vs liposomal) alone. The prices are for vitamin c (ascorbic acid vs buffered vs liposomal) products only.
From
$0.68 a month
at 200 mg a day · HerbsPro NOW Foods Vitamin C-500, 100 Tabs
Up to $9.73 a month for the most expensive of 3.
Studied dose: 200 mg/day: lowest daily dose in the Cochrane cold trials. Prices checked Oct 11 to 15, 2026.
All 3 products, cheapest first
Vitamin C (ascorbic acid vs buffered vs liposomal): every product we priced, per month at 200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Vitamin C-500, 100 Tabs $0.68 500 mg1 per serving 0.4 $5.62, 100 No certification named Oct 14, 2026 on herbspro.com Renue by Science Renue by Science LIPO Vitamin C, liposomal capsules (120) $3.54 1,000 mg2 per serving 0.2 $34.95, 60 No certification named Oct 15, 2026 on renuebyscience.com Supersmart Liposomal Vitamin C (Quali-C) $9.73 1,000 mg3 per serving 0.2 $48.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts vitamin C per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
3Melatonin
BGrade BEarlier sleep onset with a delayed body clock
RCT, 116 people, 2018. PMID 29912983 (opens in new tab)
From
$0.76 a month
at 0.5 mg a day · Botanic Choice Botanic Choice Melatonin 3 mg Dual Release, 60 vege capsules
Up to $5.06 a month for the most expensive of 5.
Studied dose: 0.5 mg: nightly dose in the delayed sleep-timing trial. Prices checked Oct 11 to 19, 2026.
All 5 products, cheapest first
Melatonin: every product we priced, per month at 0.5 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Botanic Choice Botanic Choice Melatonin 3 mg Dual Release, 60 vege capsules $0.76 3 mg1 per serving 0.17 $9.00, 60 No certification named Oct 19, 2026 on botanicchoice.com Botanic Choice Botanic Choice Melatonin 1 mg, 120 tablets $0.89 1 mg1 per serving 0.5 $7.00, 120 No certification named Oct 19, 2026 on botanicchoice.com HerbsPro Natrol Melatonin Fast Dissolve, Strawberry, 1 mg, 90 Tabs $1.28 1 mg1 per serving 0.5 $7.60, 90 No certification named Oct 19, 2026 on herbspro.com Supersmart Melatonin Supplement (1 mg tablets) $1.77 1 mg1 per serving 0.5 $14.00, 120 No certification named Oct 11, 2026 on us.supersmart.com Renue by Science Renue by Science LIPO Melatonin, liposomal capsules (90) $5.06 1 mg1 per serving 0.5 $29.95, 90 No certification named Oct 15, 2026 on renuebyscience.com Amount per serving counts melatonin per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
4Ornithine
DGrade DStress hormones, mood and perceived sleep quality
RCT, 52 people, 2014. PMID 24889392 (opens in new tab)
From
$3.29 a month
at 400 mg a day · HerbsPro NOW Foods L-Ornithine, 500 mg, 120 Caps
Studied dose: 400 mg/day: 8-week stress and sleep trial. Prices checked Oct 14, 2026.
The one product we priced
Ornithine: every product we priced, per month at 400 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Ornithine, 500 mg, 120 Caps $3.29 1,500 mg3 per serving 0.27 $16.23, 40 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts l-ornithine per serving (mg). Prices are one-time, before tax and shipping.
5Rutin
DGrade DBlood sugar, insulin resistance and lipids in type 2 diabetes
RCT, 50 people, 2023. PMID 36101997 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, leg swelling in chronic venous insufficiency (phlebotonic drugs, including rutosides).
From
$3.77 a month
at 500 mg a day · HerbsPro NOW Foods Rutin, 450 mg, 100 Vcaps
Studied dose: 500 mg/day: dose in both plain-rutin trials. Prices checked Oct 14, 2026.
The one product we priced
Rutin: every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Rutin, 450 mg, 100 Vcaps $3.77 450 mg1 per serving 1.11 $11.16, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts rutin per serving (mg). Prices are one-time, before tax and shipping.
6Creatine monohydrate
BGrade BLean mass and strength in postmenopausal women
Meta-analysis, 608 people, 2026. PMID 42141930 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade A, muscular power and strength across lifts; grade A, lean body mass; grade A, muscle strength with resistance training.
From
$4.10 a month
at 5 g a day · Micro Ingredients Creatine Monohydrate powder
Up to $86.90 a month for the most expensive of 18.
Lowest with a third-party certification: Naked Nutrition Naked Creatine (NSF Contents Certified), $5.47 a month.
Studied dose: 5 g/day: amount linked to gains in postmenopausal women who trained. Prices checked Oct 8 to 20, 2026.
All 18 products, cheapest first
Creatine monohydrate: every product we priced, per month at 5 g a day Product Per month Per serving Servings a day Price, servings Certification Checked Micro Ingredients Creatine Monohydrate powder · powder $4.10 5 g 1 $26.99, 200one-time (Amazon; list $29.95) No certification named Oct 10, 2026 on amazon.com BulkSupplements Creatine Monohydrate · powder $4.56 5 g 1 $29.97, 200 No certification named Oct 10, 2026 on bulksupplements.com Naked Nutrition Naked Creatine · powder $5.47 5 g 1 $35.99, 200 NSF Contents Certified Oct 10, 2026 on nakednutrition.com Nutricost Creatine Monohydrate powder · powder $7.29 5 g 1 $23.97, 100 No certification named Oct 10, 2026 on nutricost.com Kaged Creatine Monohydrate · powder $7.60 5 g1 scoop (5.1 g) 1 $24.99, 100 Informed Sport Oct 10, 2026 on kaged.com NOW Sports Creatine Monohydrate powder · powder $8.10 5 g1.5 tsp (about 5 g) 1 $11.99, 45one-time (sale, regular $15.99) Informed Sport Oct 10, 2026 on nowfoods.com Optimum Nutrition Micronized Creatine Monohydrate powder · powder $8.11 5 g 1 $31.99, 120 No certification named Oct 10, 2026 on optimumnutrition.com Onnit Onnit Creatine, unflavored (90-serving tub) $12.84 5 gone serving 1 $37.99, 90 No certification named Oct 20, 2026 on onnit.com Dr. Tobias Dr. Tobias Creatine Monohydrate (90 tablets) $13.72 4.8 g3 per serving 1.04 $12.99, 30 No certification named Oct 14, 2026 on drtobias.com Momentous Momentous Creatine, 90 servings $14.53 5 gone serving 1 $42.99, 90 No certification named Oct 15, 2026 on livemomentous.com Thorne Creatine · powder $14.87 5 g1 scoop 1 $44.00, 90 NSF Certified for Sport Oct 10, 2026 on thorne.com ProHealth Longevity Creatine Pure Powder $16.88 5 g1 scoop (5 g) 1 $49.95, 90 No certification named Oct 8, 2026 on prohealth.com Klean Athlete Klean Creatine · powder $17.49 5 g1 scoop (about 5 g) 1 $34.50, 60 No certification named Oct 10, 2026 on kleanathlete.com Supersmart 3-Creatine $21.00 3 gone serving 1.67 $29.00, 70 No certification named Oct 11, 2026 on us.supersmart.com Legion Creatine Gummies · gummy $40.55 5 g4 gummies 1 $39.99, 30 No certification named Oct 10, 2026 on legionathletics.com Momentous Momentous Creatine Chews, 150 count $50.68 1 g1 per serving 5 $49.99, 150 No certification named Oct 19, 2026 on livemomentous.com Create Wellness Creatine Monohydrate Gummies · gummy $75.48 4.5 g3 gummies 1.11 $201.00, 90one-time (struck $218) NSF Certified for Sport Oct 10, 2026 on trycreate.co Bear Balanced Creatine Gummies · gummy $86.90 3.5 g3 gummies 1.43 $60.00, 30 Informed Sport Oct 10, 2026 on creatinegummies.com Amount per serving counts creatine monohydrate per serving (g, from Supplement Facts). Prices are one-time, before tax and shipping.
7Magnesium taurate
DGrade DBlood pressure in adults with elevated BP
Observational, 121 people, 2026. PMID 42439043 (opens in new tab)
Tested form: magnesium taurate with potassium citrate, plus lifestyle counselling, not magnesium taurate alone. The prices are for magnesium taurate products only.
From
$4.54 a month
at 121 mg a day · Life Extension Magnesium Taurate
Studied dose: 121 mg/day: magnesium in the single-arm blood pressure study. Prices checked Oct 10, 2026.
The one product we priced
Magnesium taurate: every product we priced, per month at 121 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Life Extension Magnesium Taurate · taurate $4.54 125 mg1 capsule 0.97 $27.75, 180 No certification named Oct 10, 2026 on lifeextension.com Amount per serving counts elemental mg of magnesium per serving, as printed on the label. Prices are one-time, before tax and shipping.
8Soy isoflavones
BGrade BHot flash frequency
Meta-analysis of 13 studies, 1,196 people, 2012. PMID 22433977 (opens in new tab)
Also graded C, as a harm: endometrial hyperplasia (safety) went up (PMID 15237003 (opens in new tab)).
From
$5.70 a month
at 54 mg a day · HerbsPro NOW Foods Soy Isoflavones, 60 mg, 120 Veg Caps
Studied dose: 54 mg/day: median dose in the hot flash meta-analysis. Prices checked Oct 14, 2026.
The one product we priced
Soy isoflavones: every product we priced, per month at 54 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Soy Isoflavones, 60 mg, 120 Veg Caps $5.70 60 mg1 per serving 0.9 $24.98, 120 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts total isoflavones per serving (mg). Prices are one-time, before tax and shipping.
9Stinging Nettle
CGrade CProstate urinary symptoms (IPSS) over 12 months
RCT, 246 people, 2004. PMID 15045190 (opens in new tab)
From
$6.83 a month
at 459 mg a day · Supersmart Nettle Root Extract
Studied dose: 459 mg/day: dose in the 12-month prostate trial. Prices checked Oct 11, 2026.
The one product we priced
Stinging Nettle: every product we priced, per month at 459 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Nettle Root Extract $6.83 1,500 mg3 per serving 0.31 $22.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts nettle root extract per serving (mg). Prices are one-time, before tax and shipping.
10Elderberry
DGrade DCold duration and severity
RCT, 312 people, 2016. PMID 27023596 (opens in new tab)
From
$8.14 a month
at 900 mg a day · HerbsPro NOW Foods Elderberry, 500 mg, 60 Veg Caps
Studied dose: 900 mg/day: travel-phase dose in the air-travel cold trial. Prices checked Oct 14, 2026.
The one product we priced
Elderberry: every product we priced, per month at 900 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Elderberry, 500 mg, 60 Veg Caps $8.14 500 mg1 per serving 1.8 $8.92, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts elderberry extract per serving (mg). Prices are one-time, before tax and shipping.
11Nattokinase
DGrade DBlood pressure in a North American hypertensive population
RCT, 79 people, 2016. PMID 27785095 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, blood pressure in prehypertension or stage 1 hypertension.
From
$8.49 a month
at 100 mg a day · HerbsPro NOW Foods Nattokinase, 100 mg, 60 Vcaps
Studied dose: 100 mg/day: dose in the North American blood-pressure trial. Prices checked Oct 14, 2026.
The one product we priced
Nattokinase: every product we priced, per month at 100 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Nattokinase, 100 mg, 60 Vcaps $8.49 100 mg1 per serving 1 $16.74, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts nattokinase per serving (mg). Prices are one-time, before tax and shipping.
12Magnesium glycinate
AGrade ABlood pressure
Meta-analysis of 34 studies, 2,028 people, 2016. PMID 27402922 (opens in new tab)
Tested form: various oral forms, not magnesium glycinate alone. The prices are for magnesium glycinate products only.
From
$9.12 a month
at 300 mg a day · Doctor's Best High Absorption Magnesium (lysinate glycinate chelate)
Up to $39.54 a month for the most expensive of 11.
Lowest with a third-party certification: Nature Made High Absorption Magnesium Glycinate 200 mg (USP Verified), $16.22 a month.
Studied dose: 300 mg/day: amount the blood-pressure meta-analysis linked to an effect. Prices checked Oct 10 to 19, 2026.
All 11 products, cheapest first
Magnesium glycinate: every product we priced, per month at 300 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Doctor's Best High Absorption Magnesium (lysinate glycinate chelate) · glycinate $9.12 200 mg2 tablets 1.5 $23.99, 120 No certification named Oct 10, 2026 on doctorsbest.com HerbsPro NOW Foods Magnesium Glycinate, 90 Tabs $11.40 200 mg2 per serving 1.5 $11.24, 45 No certification named Oct 14, 2026 on herbspro.com Dr. Tobias Dr. Tobias Magnesium Bisglycinate (120 capsules) $11.40 200 mg1 per serving 1.5 $29.99, 120 No certification named Oct 14, 2026 on drtobias.com Toplux Magnesium Glycinate · glycinate $11.57 525 mg3 capsules 0.57 $19.97, 30one-time (Amazon; list $29.97) No certification named Oct 10, 2026 on amazon.com NOW Foods Magnesium Glycinate tablets · glycinate $12.16 200 mg2 tablets 1.5 $23.99, 90one-time (sale, regular $31.99) No certification named Oct 10, 2026 on nowfoods.com Nature Made High Absorption Magnesium Glycinate 200 mg · glycinate $16.22 200 mg2 capsules 1.5 $31.99, 90one-time (Amazon) USP Verified Oct 10, 2026 on amazon.com Pure Encapsulations Magnesium (glycinate) · glycinate $19.64 120 mg1 capsule 2.5 $46.50, 180 No certification named Oct 10, 2026 on pureforyou.com Klean Athlete Klean Magnesium · glycinate $22.39 120 mg1 capsule 2.5 $26.50, 90 No certification named Oct 10, 2026 on kleanathlete.com Botanic Choice Botanic Choice Magnesium Glycinate, 240 mg, 60 capsules $25.35 240 mg2 per serving 1.25 $20.00, 30 No certification named Oct 19, 2026 on botanicchoice.com Momentous Momentous Magnesium Bisglycinate, 60 capsules $25.84 200 mg2 per serving 1.5 $16.99, 30 No certification named Oct 15, 2026 on livemomentous.com Supersmart Magnesium Bisglycinate (Albion TRAACS) $39.54 300 mg4 per serving 1 $39.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts magnesium per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
13Devil's Claw
CGrade CPain-free days during a flare of chronic low back pain
RCT, 197 people, 1999. PMID 10101629 (opens in new tab)
From
$9.50 a month
at 1,200 mg a day · HerbsPro Nature's Way Devil's Claw Root, 100 Caps
Studied dose: 1,200 mg/day: WS 1531 extract (100 mg harpagoside) in the back pain trial. Prices checked Oct 15, 2026.
The one product we priced
Devil's Claw: every product we priced, per month at 1,200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Nature's Way Devil's Claw Root, 100 Caps $9.50 960 mg2 per serving 1.25 $12.49, 50 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts devil's claw per serving (mg). Prices are one-time, before tax and shipping.
14Lysine
DGrade DRecurrent herpes simplex: outbreaks, severity and time to clear
RCT, 52 people, 1987. PMID 3115841 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade C, diarrhea and respiratory illness days.
From
$10.17 a month
at 3,000 mg a day · HerbsPro NOW Foods L-Lysine, 500 mg, 100 Tabs
Up to $27.38 a month for the most expensive of 3.
Studied dose: 3,000 mg/day: dose in the 1987 six-month trial. Prices checked Oct 11 to 14, 2026.
All 3 products, cheapest first
Lysine: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Lysine, 500 mg, 100 Tabs $10.17 500 mg1 per serving 6 $5.57, 100 No certification named Oct 14, 2026 on herbspro.com Dr. Tobias Dr. Tobias L-Lysine 500 mg (100 tablets) $18.23 500 mg1 per serving 6 $9.99, 100 No certification named Oct 14, 2026 on drtobias.com Supersmart L-Lysine $27.38 3,000 mg6 per serving 1 $27.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts l-lysine per serving (mg). Prices are one-time, before tax and shipping.
15Pantothenic Acid (Vitamin B5)
DGrade DFacial acne lesion count
RCT, 41 people, 2014. PMID 24831048 (opens in new tab)
Tested form: pantothenic acid-based dietary supplement (Pantothen tablets), not pantothenic acid (vitamin b5) alone. The prices are for pantothenic acid (vitamin b5) products only.
From
$10.45 a month
at 2,200 mg a day · HerbsPro NOW Foods Pantothenic Acid, 500 mg, 100 Caps
Studied dose: 2,200 mg/day: acne trial. Prices checked Oct 14, 2026.
The one product we priced
Pantothenic Acid (Vitamin B5): every product we priced, per month at 2,200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Pantothenic Acid, 500 mg, 100 Caps $10.45 500 mg1 per serving 4.4 $7.81, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts pantothenic acid per serving (mg). Prices are one-time, before tax and shipping.
16Bromelain
CGrade CPain, swelling and quality of life after wisdom tooth removal
RCT, 45 people, 2014. PMID 24589242 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade B, need for surgical excision in deep burns (prescription topical bromelain).
From
$10.81 a month
at 1,000 mg a day · Botanic Choice Botanic Choice Bromelain, 500 mg, 90 capsules
Up to $13.94 a month for the most expensive of 2.
Studied dose: 1,000 mg/day: wisdom tooth surgery trial. Prices checked Oct 12 to 14, 2026.
All 2 products, cheapest first
Bromelain: every product we priced, per month at 1,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Botanic Choice Botanic Choice Bromelain, 500 mg, 90 capsules $10.81 500 mg1 per serving 2 $16.00, 90 No certification named Oct 12, 2026 on botanicchoice.com HerbsPro NOW Foods Bromelain, 500 mg, 120 Veg Caps $13.94 500 mg1 per serving 2 $27.49, 120 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts bromelain per serving (mg). Prices are one-time, before tax and shipping.
17White Kidney Bean Extract
CGrade CWeight and fat loss during calorie restriction (Phase 2 extract)
RCT, 81 people, 2024. PMID 38830962 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for it: grade B, body weight and fat mass in overweight and obesity.
From
$15.15 a month
at 3,000 mg a day · HerbsPro Nutricost White Kidney Bean Capsules, 120 Count
Studied dose: 3,000 mg/day: higher Phase 2 and Phaseolean dose. Prices checked Oct 15, 2026.
The one product we priced
White Kidney Bean Extract: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Nutricost White Kidney Bean Capsules, 120 Count $15.15 650 mg1 per serving 4.62 $12.95, 120 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts white kidney bean extract per serving (mg). Prices are one-time, before tax and shipping.
18Artichoke Extract
CGrade CFunctional dyspepsia symptoms and quality of life
RCT, 247 people, 2003. PMID 14653829 (opens in new tab)
From
$17.69 a month
at 1,920 mg a day · HerbsPro NOW Foods Artichoke Extract, 450 mg, 90 Vcaps
Studied dose: 1,920 mg/day: dose in the functional dyspepsia trial. Prices checked Oct 14, 2026.
The one product we priced
Artichoke Extract: every product we priced, per month at 1,920 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Artichoke Extract, 450 mg, 90 Vcaps $17.69 450 mg1 per serving 4.27 $12.27, 90 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts artichoke leaf extract per serving (mg). Prices are one-time, before tax and shipping.
19L-theanine
BGrade BAttention (choice reaction time) and acute stress
Meta-analysis, 1,168 people, 2026. PMID 42410082 (opens in new tab)
Tested form: l-theanine (oral), not l-theanine alone. The prices are for l-theanine products only.
From
$20.27 a month
at 200 mg a day · Momentous Momentous L-Theanine, 60 capsules
Up to $20.28 a month for the most expensive of 2.
Studied dose: 200 mg: single dose in the attention trials. Prices checked Oct 11 to 15, 2026.
All 2 products, cheapest first
L-theanine: every product we priced, per month at 200 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Momentous Momentous L-Theanine, 60 capsules $20.27 200 mg1 per serving 1 $39.99, 60 No certification named Oct 15, 2026 on livemomentous.com Supersmart L-Theanine $20.28 400 mg4 per serving 0.5 $20.00, 15 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts l-theanine per serving (mg, from Supplement Facts). Prices are one-time, before tax and shipping.
20L-Histidine
DGrade DInsulin resistance (HOMA-IR), body fat and inflammatory markers
RCT, 92 people, 2013. PMID 23361591 (opens in new tab)
From
$52.79 a month
at 4,000 mg a day · HerbsPro NOW Foods L-Histidine, 600 mg, 60 VegCaps
Studied dose: 4,000 mg/day: dose in the eczema and insulin-resistance trials. Prices checked Oct 14, 2026.
The one product we priced
L-Histidine: every product we priced, per month at 4,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods L-Histidine, 600 mg, 60 VegCaps $52.79 600 mg1 per serving 6.67 $15.62, 60 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts l-histidine per serving (mg). Prices are one-time, before tax and shipping.
21Bitter melon
DGrade DFasting glucose and insulin resistance in prediabetes (freeze-dried fruit)
RCT, 38 people, 2025. PMID 40199408 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade C, fasting glucose and HbA1c in type 2 diabetes (pooled trials); grade C, total cholesterol and triglycerides (pooled RCTs).
From
$63.84 a month
at 3,600 mg a day · HerbsPro Solaray Bitter Melon Fruit Extract, 500 mg, 60 Caps
Studied dose: 3,600 mg/day: 12-week prediabetes trial. Prices checked Oct 15, 2026.
The one product we priced
Bitter melon: every product we priced, per month at 3,600 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro Solaray Bitter Melon Fruit Extract, 500 mg, 60 Caps $63.84 500 mg1 per serving 7.2 $17.49, 60 No certification named Oct 15, 2026 on herbspro.com Amount per serving counts bitter melon (dried fruit or extract) per serving (mg). Prices are one-time, before tax and shipping.
22Glutathione (oral)
CGrade CSkin melanin index
RCT, 60 people, 2012. PMID 20524875 (opens in new tab)
From
$67.53 a month
at 500 mg a day · Renue by Science Renue by Science LIPO Glutathione, liposomal capsules (90)
Studied dose: 500 mg/day: dose in the 4-week skin-lightening trial. Prices checked Oct 15, 2026.
The one product we priced
Glutathione (oral): every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Renue by Science Renue by Science LIPO Glutathione, liposomal capsules (90) $67.53 130 mg1 per serving 3.85 $51.95, 90 No certification named Oct 15, 2026 on renuebyscience.com Amount per serving counts glutathione per serving (mg). Prices are one-time, before tax and shipping.
23Inositol
BGrade BRegular menstrual periods in PCOS
Meta-analysis of 26 studies, 1,691 people, 2023. PMID 36703143 (opens in new tab)
Tested form: myo-inositol, D-chiro-inositol or both, not inositol alone. The prices are for inositol products only.
From
$67.57 a month
at 4,000 mg a day · Momentous Momentous Inositol, 120 capsules
Studied dose: 4,000 mg/day: most common PCOS trial dose and the pregnancy trial dose. Prices checked Oct 15, 2026.
The one product we priced
Inositol: every product we priced, per month at 4,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Momentous Momentous Inositol, 120 capsules $67.57 900 mg2 per serving 4.44 $29.99, 60 No certification named Oct 15, 2026 on livemomentous.com Amount per serving counts myo-inositol per serving (mg). Prices are one-time, before tax and shipping.
24Sea Buckthorn
DGrade DVaginal dryness and tissue health after menopause
RCT, 116 people, 2014. PMID 25104582 (opens in new tab)
From
$106.46 a month
at 3,000 mg a day · Supersmart Sea Buckthorn Extract Supplement
Studied dose: 3,000 mg/day: vaginal dryness trial. Prices checked Oct 11, 2026.
The one product we priced
Sea Buckthorn: every product we priced, per month at 3,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Sea Buckthorn Extract Supplement $106.46 1,000 mg2 per serving 3 $35.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Amount per serving counts sea buckthorn oil per serving (mg). Prices are one-time, before tax and shipping.
25Urolithin A
CGrade CMuscle strength and endurance in middle-aged adults
RCT, 88 people, 2022. PMID 35584623 (opens in new tab)
From
$108.49 a month
at 500 mg a day · Supersmart Urolithin A
Studied dose: 500 mg/day: low dose in the middle-aged trial. Prices checked Oct 12, 2026.
The one product we priced
Urolithin A: every product we priced, per month at 500 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Urolithin A $108.49 500 mg2 per serving 1 $107.00, 30 No certification named Oct 12, 2026 on us.supersmart.com Amount per serving counts urolithin A per serving (mg). Prices are one-time, before tax and shipping.
26Activated Charcoal
DGrade DTotal and LDL cholesterol vs cholestyramine and bran
Crossover RCT, 10 people, 1989. PMID 2612535 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade C, functional dyspepsia symptoms (charcoal, simethicone and magnesium oxide); grade C, dyspepsia symptoms (charcoal plus simethicone).
From
$119.41 a month
at 16,000 mg a day · HerbsPro NOW Foods Activated Charcoal, 200 Veg Caps
Studied dose: 16,000 mg/day: cholesterol crossover study. Prices checked Oct 14, 2026.
The one product we priced
Activated Charcoal: every product we priced, per month at 16,000 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked HerbsPro NOW Foods Activated Charcoal, 200 Veg Caps $119.41 560 mg2 per serving 28.57 $13.74, 100 No certification named Oct 14, 2026 on herbspro.com Amount per serving counts activated charcoal per serving (mg). Prices are one-time, before tax and shipping.
27Cannabidiol (CBD)
DGrade DAnxiety during a simulated public speaking test in social anxiety disorder
RCT, 24 people, 2011. PMID 21307846 (opens in new tab)
Graded higher on its page but not priced, because no single studied daily dose is recorded for them: grade A, seizure frequency in treatment-resistant epilepsy (prescription CBD); grade C, anxiety symptoms across anxiety disorders.
Also graded B, as a harm: pain intensity in fibromyalgia went up (PMID 40846590 (opens in new tab)).
From
$231.17 a month
at 600 mg a day · Neurogan Neurogan CBD Softgels Extra Strength (60 count)
Up to $1,216.42 a month for the most expensive of 2.
Studied dose: 600 mg: social anxiety trial single dose. Prices checked Oct 16, 2026.
All 2 products, cheapest first
Cannabidiol (CBD): every product we priced, per month at 600 mg a day Product Per month Per serving Servings a day Price, servings Certification Checked Neurogan Neurogan CBD Softgels Extra Strength (60 count) $231.17 125 mg1 per serving 4.8 $95.00, 60 No certification named Oct 16, 2026 on neurogan.com Green Roads Green Roads CBD Softgels 25mg (30 count) $1,216.42 25 mg1 per serving 24 $49.99, 30 No certification named Oct 16, 2026 on greenroads.com Amount per serving counts cBD per serving (mg). Prices are one-time, before tax and shipping.
28Bovine colostrum
CGrade CSelf-reported upper respiratory symptoms
RCT, 174 people, 2003. PMID 12923655 (opens in new tab)
Also graded C, as a harm: intestinal permeability during running training went up (PMID 22253980 (opens in new tab)).
From
$1,581.67 a month
at 60 g a day · Supersmart Colostrum
Up to $1,736.79 a month for the most expensive of 2.
Studied dose: 60 g/day: dose in the respiratory symptom and running trials. Prices checked Oct 11 to 20, 2026.
All 2 products, cheapest first
Bovine colostrum: every product we priced, per month at 60 g a day Product Per month Per serving Servings a day Price, servings Certification Checked Supersmart Colostrum $1,581.67 1 g2 per serving 60 $26.00, 30 No certification named Oct 11, 2026 on us.supersmart.com Physician’s Choice Physician’s Choice Colostrum Gold Powder, unflavored (30 servings) $1,736.79 2 gone serving 30 $57.10, 30 No certification named Oct 20, 2026 on physicianschoice.com Amount per serving counts bovine colostrum per serving (g). Prices are one-time, before tax and shipping.
How this index works
What “evidence per dollar” means here. Two things side by side: how strong the research is for a supplement's best-supported benefit (its grade), and what it costs a month to take the amount that research used. We do not merge them into one score. A grade is a ranking of certainty, not a quantity, so dividing it by a price would invent a precision the evidence does not have.
The grade. Each grade is the one the supplement's own page shows, for one outcome. We take the benefit outcomes graded A to D and choose the strongest that has a studied daily dose on record: the best grade first, then a trial of that exact form, then more people. A goal view does the same within that goal's outcomes, so one supplement can sit at a different grade and price under two goals. The grade scale, word for word from our methodology:
- AGrade AAt least two concordant randomized controlled trials (RCTs), or a meta-analysis of RCTs, with a combined total of 300 or more participants.
- BGrade BAt least one adequately powered RCT, or a consistent set of smaller RCTs.
- CGrade CSmall or short RCTs, or trials with mixed results.
- DGrade DA single small trial, or uncontrolled human data (open-label, before-and-after).
- ∅No effectAdequately powered RCTs that found no effect on the outcome.
The dose. The daily amount the supplement's page records for the study behind that outcome, joined by the study it cites. Never an upper limit, and never a dose we chose.
The price. Only products with a price, the date it was checked, a number of servings and an amount per serving: the price per effective doseindex, our brand reviews, and the Where to buy lists on our supplement pages. For a Where to buy row we read the amount per serving and the servings from the label line we copied from the product page. When a line is ambiguous (an extract's weight rather than its active, two ingredients, no bottle count) we leave the product out and list it below rather than guess. Prices are one-time, before tax and shipping.
The formula. Monthly cost = price ÷ (servings × amount per serving) × studied daily dose × 30.4 days (365 ÷ 12).
The order. Grade first, then the monthly cost of the product in the top spot. The top spot goes to the cheapest product whose brand passed our vetting without conditions, or that we hold no adverse record for. A brand with only a conditional pass, or with a regulator letter or an independent lab finding on record, is still listed at its price but is never placed first. A tie goes to the product with a third-party certification. Commissions, partner status and brand priority are not inputs.
What it does not tell you. Absorption and quality differ between products and forms, and label amounts are the brand's. Where the evidence pooled several forms, the row says so. A grade from one group of people (for example postmenopausal women) may not carry over to others. Prices change, so check before you buy. And a low cost is no reason to take something you do not need.
Listed but not priced
48 products on our supplement pages that the index leaves out: no dated price on record (price not checked), or a label line we could not read into numbers.
Price not checked
0 productsEvery product on our supplement pages has a one-time price with a checked date.
Label amount not read
48 products- 7-Keto 25 mgSupersmart · on 7-Keto DHEANo amount of 3-acetyl-7-keto-DHEA per serving in the label line.
- Planetary Herbals Amla Superfruit, 500 mg, 60 TabsHerbsPro · on AmlaNo amount of Amla extract per serving in the label line.
- Renue by Science LIPO Apigenin, liposomal capsules (90)Renue by Science · on ApigeninNo servings or bottle count named.
- NOW Foods Beet Root Powder, 12 OzHerbsPro · on BeetrootNo amount of Dietary nitrate per serving in the label line.
- BioperineSupersmart · on Black PepperNo amount of Piperine per serving in the label line.
- Nature's Way Black Seed Oil, 8 ozHerbsPro · on Black seed (Nigella sativa)No amount of Black seed oil or powder per serving in the label line.
- Renue by Science LIPO CaAKG, liposomal capsules (90 x 300 mg)Renue by Science · on Calcium alpha-ketoglutarate (Ca-AKG)No amount of Ca-AKG per serving in the label line.
- Calcium AKGSupersmart · on Calcium alpha-ketoglutarate (Ca-AKG)No amount of Ca-AKG per serving in the label line.
- Green Roads Broad Spectrum CBD Oil 1500mg (30 mL)Green Roads · on Cannabidiol (CBD)The label line does not say what one serving is.
- Neurogan Broad Spectrum CBD Oil 2000MG, THC-free (30 mL)Neurogan · on Cannabidiol (CBD)The label line does not say what one serving is.
- NOW Foods Chlorella, 500 mg, 200 TabsHerbsPro · on Chlorella200 pieces do not divide into servings of 6.
- NOW Foods Collagen Peptides Powder, 8 OzHerbsPro · on Collagen peptidesNo amount of Collagen peptides per serving in the label line.
- Sports Research Collagen Peptides, unflavored (16 oz)Sports Research · on Collagen peptidesNo servings per container in the label line.
- Bio Nutrition CLA 1500, 60 SoftgelsHerbsPro · on Conjugated Linoleic Acid (CLA)No amount of CLA per serving in the label line.
- Cran-MaxSupersmart · on CranberryNo amount of Proanthocyanidins (PACs) per serving in the label line.
- NOW Foods Creatine Monohydrate Micronized Powder, 1.1 lbHerbsPro · on Creatine monohydrateThe label line does not say what one serving is.
- NOW Foods D-Ribose Powder, 8 ozHerbsPro · on D-riboseNo servings per container in the label line.
- DIM (Diindolylmethane)Supersmart · on DIM (diindolylmethane)The label line says this product is not the form or format the trials tested.
- Nature's Way Siberian Eleuthero Root, 100 CapsHerbsPro · on Eleuthero (Siberian ginseng)No amount of Eleuthero root extract per serving in the label line.
- Solaray Flaxseed Oil, 100 SoftgelsHerbsPro · on FlaxseedNo amount of Milled flaxseed per serving in the label line.
- GlyNACSupersmart · on GlyNAC (Glycine + N-Acetylcysteine)The basis names two ingredients.
- Renue by Science LIPO HLA hyaluronic acid, liposomal capsules (90)Renue by Science · on Hyaluronic AcidNo servings or bottle count named.
- Hyaluronic AcidSupersmart · on Hyaluronic AcidNo amount of Hyaluronic acid per serving in the label line.
- NOW Foods Inositol, 500 mg, 100 capsulesHerbsPro · on InositolNo amount of Myo-inositol per serving in the label line.
- NOW Foods L-Leucine Powder, 9 ozHerbsPro · on L-LeucineNo servings per container in the label line.
- NOW Foods Maca, 750 mg, 90 VcapsHerbsPro · on MacaNo amount of Maca root powder per serving in the label line.
- Super MacaSupersmart · on MacaNo amount of Maca root powder per serving in the label line.
- NOW Foods Liquid Melatonin, 3 mg, 2 ozHerbsPro · on MelatoninThe label line does not say what one serving is.
- Nattokinase SupplementSupersmart · on NattokinaseNo amount of Nattokinase per serving in the label line.
- Oreganol P73 GelcapsNorth American Herb & Spice · on OreganoThe label does not state the amount of the active in a serving.
- Oreganol P73 OilNorth American Herb & Spice · on OreganoThe label does not state the amount of the active in a serving.
- Super Strength Oreganol P73North American Herb & Spice · on OreganoThe label does not state the amount of the active in a serving.
- Super Strength Oreganol P73 GelcapsNorth American Herb & Spice · on OreganoThe label does not state the amount of the active in a serving.
- Oil of Oregano SupplementSupersmart · on OreganoThe label line does not say what one serving is.
- Source Naturals Beta Sitosterol Mega Strength, 375 mg, 120 TabsHerbsPro · on Phytosterols (plant sterols and stanols)No amount of Plant sterols per serving in the label line.
- Potassium Orotate SupplementSupersmart · on Potassium (chloride vs citrate vs gluconate)No amount of Elemental potassium per serving in the label line.
- Botanic Choice Pygeum Bark, 500 mg, 60 capsulesBotanic Choice · on PygeumNo amount of Pygeum extract per serving in the label line.
- NOW Foods Red Clover, 375 mg, 100 CapsHerbsPro · on Red CloverNo amount of Red clover isoflavones per serving in the label line.
- Botanic Choice Saw Palmetto, 500 mg, 90 capsulesBotanic Choice · on Saw palmettoNo amount of Saw palmetto extract per serving in the label line.
- NOW Foods Vitamin B-1, 100 mg, 100 TabsHerbsPro · on Thiamine (Vitamin B1)No amount of Thiamine HCl per serving in the label line.
- Nutricost Holy Basil Capsules, 120 CountHerbsPro · on Tulsi (Holy Basil)No amount of Tulsi extract per serving in the label line.
- Dr. Tobias Turmeric Curcumin (120 capsules)Dr. Tobias · on Turmeric and curcuminNo amount of Curcuminoids per serving in the label line.
- NOW Foods Turmeric Curcumin, 60 Veg CapsHerbsPro · on Turmeric and curcuminNo amount of Curcuminoids per serving in the label line.
- Momentous Turmeric, 60 capsulesMomentous · on Turmeric and curcuminNo amount of Curcuminoids per serving in the label line.
- Curcumin Solution (NovaSOL)Supersmart · on Turmeric and curcuminNo amount of Curcuminoids per serving in the label line.
- JSHealth Vitamins Vegan Vitamin D Formula (2-month supply)JSHealth Vitamins · on Vitamin D3 vs D2No servings or bottle count named.
- NOW Foods Sun-E 400, 60 SoftgelsHerbsPro · on Vitamin E (natural d-alpha vs synthetic dl-alpha tocopherol)No amount of Vitamin E per serving in the label line.
- NOW Foods ZMA, 90 Veg CapsHerbsPro · on ZMA (Zinc Magnesium Aspartate)No amount of Elemental zinc per serving in the label line.
Not in the index yet
350 of 379 supplements with a price or a studied dose on record, grouped by what is missing.
204No studied daily dose recorded on its page; and prices are listed, but the amount per serving and servings are only in label text
5-HTP, Acacia Fiber, Açaí, Acetyl-L-carnitine, Agaricus blazei (Royal Sun Mushroom), AHCC (Active Hexose Correlated Compound), Allulose, Aloe Vera, Alpha-Galactosidase, Alpha-GPC, Alpha-lipoic acid, American Skullcap, Andrographis, Apple Cider Vinegar, Apple pectin, Arginine Alpha-Ketoglutarate (AAKG), Astaxanthin, Astragalus, Bacillus subtilis, Bacopa monnieri, BCAAs (branched-chain amino acids), Bee Pollen, Benfotiamine, Berberine (vs dihydroberberine), Beta-alanine, Beta-glucans, Bifidobacterium lactis, Bifidobacterium longum, Bilberry (Vaccinium myrtillus), Biotin, Black cohosh, Borage Oil (GLA), Boron, Boswellia, Brewer's Yeast (Inactive), Burdock Root (Arctium lappa), Butcher's broom, Butterbur, Caffeine (capsules, gum and anhydrous powder), Calcium (carbonate vs citrate), Cannabinol (CBN), Carnitine (L-carnitine, L-carnitine L-tartrate, acetyl-L-carnitine), Carnosine, Ceramides (oral phytoceramides), Cetylated Fatty Acids (Celadrin), Chasteberry (Vitex), Chia Seed, Choline (bitartrate vs alpha-GPC vs phosphatidylcholine), Chondroitin, Chromium, Cinnamon, Citicoline, Citrulline (L-citrulline and citrulline malate), Citrus bergamot, Cod liver oil, Copper, CoQ10 (ubiquinol vs ubiquinone), Cordyceps, D-mannose, Dandelion, DHEA, Digestive enzymes, Dihydromyricetin (DHM), Diosmin, DMAE (Deanol), Dong Quai, Echinacea, EpiCor (dried yeast fermentate), Ergothioneine, Essential Amino Acids (EAAs), Evening primrose oil, Fenugreek, Feverfew, Flower pollen extract, Folate (methylfolate vs folic acid), Fucoidan, GABA, Gamma-oryzanol, Gamma-Tocopherol, Garlic, Ginger, Ginkgo biloba, Glucomannan (konjac), Glucosamine, Glycine, Gotu kola, L. rhamnosus GR-1 and L. reuteri RC-14, Green tea extract (EGCG), Guggul, Gymnema Sylvestre, Hawthorn, Hibiscus (Hibiscus sabdariffa), HMB (beta-hydroxy-beta-methylbutyrate), Horsetail, Inulin (inulin-type fructans), Iodine (potassium iodide, kelp), IP6 (Inositol Hexaphosphate, Phytate), Krill oil, L-arginine, L-glutamine, L-Methionine, L-Ornithine L-Aspartate (LOLA), L-tryptophan, L-tyrosine, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus reuteri, Lactobacillus salivarius (Ligilactobacillus salivarius), Lactoferrin, Larch Arabinogalactan, Lavender (oral lavender oil), Lemon balm, Lemon Verbena (Aloysia), Licorice root (Glycyrrhiza glabra), Lion's mane mushroom, Lithothamnion (Aquamin), Lumbrokinase (Earthworm), Lutein and zeaxanthin, Lycopene, Magnesium, Magnesium chloride, Magnesium orotate, Magnolia bark, Maqui Berry, Marshmallow Root, Mastic gum, MCT oil (medium-chain triglycerides), Melon SOD (GliSODin), Milk Thistle (Silymarin), Modified Citrus Pectin, Moringa, MSM (methylsulfonylmethane), Multivitamin (multivitamin/mineral), Myricetin, N-Acetyl Glucosamine (NAG), NAC (N-acetylcysteine), NADH, Niacin (nicotinic acid), Niacinamide (nicotinamide), Nicotinamide riboside (NR), Nopal (Prickly Pear Cactus), Olive leaf extract, Oral ATP (Adenosine Triphosphate), PABA (Para-Aminobenzoic Acid), Palmitoylethanolamide (PEA), Panax Ginseng (Asian Ginseng), Panax notoginseng, Pantethine, Peppermint Oil, Phellodendron (Amur Cork Tree Bark), Phosphatidylserine, Polydextrose, Polypodium leucotomos, Probiotics, Propolis, Prunes (Dried Plums), Psyllium, Pterostilbene, Pycnogenol (French maritime pine bark extract), Pyruvate, Quercetin, Red yeast rice, Reishi mushroom, Resveratrol, Rhodiola rosea, Brown Rice Protein, Rosemary Oil, Royal jelly, Saccharomyces boulardii, Saffron, SAMe (S-adenosyl-L-methionine), Schisandra, Selenium (selenomethionine vs selenite), Serrapeptase, Shatavari, Shiitake, Shilajit, Slippery elm, Sodium Citrate (Trisodium), Spermidine, Spirulina, Streptococcus salivarius K12, Sulforaphane (broccoli sprout extract), Tart cherry, Taurine, Taxifolin, Tocotrienols, Tongkat ali, Tribulus Terrestris, Trigonelline, TMG (trimethylglycine, betaine), Triphala, TUDCA (tauroursodeoxycholic acid), Turkey tail mushroom (Trametes versicolor), Ursolic acid, Valerian Root, Vitamin B complex, Vitamin K1 (Phylloquinone), Vitamin K2 (MK-7 vs MK-4), Wheat Dextrin, Whey protein (and other protein powders), Willow bark, Xanthohumol, Zinc carnosine.
73No price on record
African Mango, Agmatine, Anserine, Bentonite Clay, Betaine HCl, Butyrate, Cannabigerol (CBG), Capsaicin (capsaicinoids and capsinoids), Capsanthin (paprika xanthophylls), Caralluma fimbriata, Cat's claw, Chitosan, Chlorophyll (Chlorophyllin), Cissus quadrangularis, Coleus Forskohlii (Forskolin), D-Aspartic Acid, D-Serine, Ellagic Acid, Exogenous Ketones, Fucoxanthin, Gelatin, Green Coffee Extract, Green mandarin extract, Hemp Protein, Hops, Hydroxytyrosol, L-Isoleucine, Jiaogulan, Kanna, Keratin, L-Serine, Lactium (alpha-s1 casein hydrolysate), Leucic acid (HICA), Lithium Orotate, Luteolin, Magnesium oxide, Manganese, Mangosteen, Methylcellulose, MicroLactin (hyperimmune milk protein), Mitoquinone (MitoQ), Molecular Hydrogen, Nitrosigine (inositol-stabilized arginine silicate), Oleoylethanolamide (OEA), Oxaloacetate, Phosphatidic Acid, Prenatal Vitamins, Rhamnogalacturonan-I (carrot RG-I), Rose Hip, Safed Musli, Sage (Salvia officinalis), Salacia reticulata, Sesamin, Silica (Silicon), Spearmint, Squalene, Strontium, Terminalia arjuna, Terminalia chebula (haritaki), Thai ginseng (Kaempferia parviflora), Theaflavins (black tea extract), Thylakoids (spinach extract), Thymus Extract, Trehalose, Troxerutin, L-Valine, Vanadium, Vitamin B6 (pyridoxine vs P5P), Wheatgrass, White Mulberry Leaf, Wild celery extract (celery seed), Yacon, Yarrow.
16no price record whose label line gives the amount per serving and the servings
Amla, Beetroot, Black seed (Nigella sativa), Calcium alpha-ketoglutarate (Ca-AKG), Chlorella, D-ribose, Flaxseed, Hyaluronic Acid, L-Leucine, Oregano, Phytosterols (plant sterols and stanols), Potassium (chloride vs citrate vs gluconate), Pygeum, Red Clover, Thiamine (Vitamin B1), Tulsi (Holy Basil).
16Its studied doses belong to other outcomes, not to a benefit we could price; and no price on record
Alpha-Linolenic Acid, Banaba Leaf, DL-Phenylalanine, Guar Gum, Human Milk Oligosaccharides (HMOs), Phosphorus, Red spinach extract, Resistant Starch, Rosmarinic acid, Sarcosine, Serum Bovine Immunoglobulin (SBI), Theacrine, Tinospora cordifolia (guduchi), Umckaloabo (Pelargonium sidoides), Uridine, Whole coffee fruit extract.
15Its studied doses belong to other outcomes, not to a benefit we could price
Apigenin, Ashwagandha, Collagen peptides, Grape seed extract, Hesperidin, Huperzine A, Iron (ferrous sulfate vs bisglycinate vs other forms), Maca, Omega-3 (fish oil, krill oil, algal oil), Policosanol, Pomegranate, Saw palmetto, Vitamin B12 (methylcobalamin vs cyanocobalamin), Vitamin D3 vs D2, Zinc (picolinate vs gluconate vs bisglycinate).
9Its studied doses belong to other outcomes, not to a benefit we could price; and no price record whose label line gives the amount per serving and the servings
7-Keto DHEA, Black Pepper, Conjugated Linoleic Acid (CLA), Cranberry, DIM (diindolylmethane), Eleuthero (Siberian ginseng), GlyNAC (Glycine + N-Acetylcysteine), Turmeric and curcumin, Vitamin E (natural d-alpha vs synthetic dl-alpha tocopherol).
6Prices are listed, but the amount per serving and servings are only in label text
Horny Goat Weed (Epimedium), Horse Chestnut, Indole-3-carbinol (I3C), Pea Protein, Pumpkin seed oil, Type II Collagen (Undenatured).
4No graded outcome has a studied daily dose; and no price on record
Acerola, Bladderwrack, D-Limonene, Uva ursi (bearberry).
3No graded outcome has a studied daily dose
Calcium D-Glucarate, Fisetin, Molybdenum.
3No studied daily dose recorded on its page
Magnesium citrate, Magnesium L-threonate, NMN (nicotinamide mononucleotide).
1No graded outcome has a studied daily dose; and no price record whose label line gives the amount per serving and the servings
ZMA (Zinc Magnesium Aspartate).
Products left out of rows that are shown: Momentous Creatine (90 servings) (the same product as the price index record, which was checked later); Momentous Longevity (combination product: its price also pays for other actives); Onnit Creatine (90 servings) (the same product as the Where to buy record, which was checked later); Onnit NMN + Creatine (30 ct) (combination product: its price also pays for other actives); ProHealth Longevity Nicotinamide Riboside Pro 300 + TMG (combination product: its price also pays for other actives); Momentous Creatine Chews (the same product as the Where to buy record, which was checked later); Momentous Creatine Monohydrate (the same product as the Where to buy record, which was checked later); Sports Research Triple Strength Omega-3 (Alaska pollock) (the same product as the Where to buy record, which was checked later); BiOptimizers Magnesium Breakthrough (form "blend (7 forms)" has no single-form monograph to take a studied dose from); Life Extension Magnesium Caps 500 mg (form "oxide blend (reference)" has no single-form monograph to take a studied dose from); Momentous Magnesium Bisglycinate (the same product as the Where to buy record, which was checked later); Physician’s Choice Physician’s Choice KSM-66 Ashwagandha (60 capsules) (combination product: its price also pays for other actives); Dr. Tobias Dr. Tobias Ashwagandha with Black Pepper (60 capsules) (combination product: its price also pays for other actives); Goli Goli Ashwagandha Gummies, 60 gummies (combination product: its price also pays for other actives); Goli Goli Beets Cardio Gummies, 60 gummies (combination product: its price also pays for other actives); Onnit Onnit Total Nitric Oxide, Harvest Fruit (20 servings) (combination product: its price also pays for other actives); CBDfx CBDfx CBD + CBG Oil Wellness Tincture (1,000 mg, 30 mL) (combination product: its price also pays for other actives); Supersmart Marine Collagen (combination product: its price also pays for other actives); Physician’s Choice Physician’s Choice Collagen Peptides Powder, unflavored (1 bag) (combination product: its price also pays for other actives); Dr. Tobias Dr. Tobias Probiotics for Women (60 capsules) (combination product: its price also pays for other actives); HerbsPro NOW Foods DIM 200 Diindolylmethane, 90 Veg Caps (combination product: its price also pays for other actives); Supersmart Liposomal Glutathione (combination product: its price also pays for other actives); HerbsPro NOW Foods Glutathione, 500 mg, 60 Vcaps (combination product: its price also pays for other actives); HerbsPro NOW Foods Horny Goat Weed Extract, 750 mg, 90 Tabs (combination product: its price also pays for other actives); HerbsPro NOW Foods Horse Chestnut, 300 mg, 90 Veg Caps (combination product: its price also pays for other actives); HerbsPro NOW Foods Hyaluronic Acid, 100 mg, 60 Vcaps (combination product: its price also pays for other actives); HerbsPro NOW Foods Indole-3-Carbinol (I3C), 200 mg, 60 veg capsules (combination product: its price also pays for other actives); Organics Ocean Better Iron (combination product: its price also pays for other actives); JSHealth Vitamins JSHealth Vitamins Iron+ Formula (1-month supply) (combination product: its price also pays for other actives); Momentous Momentous Iron+, 60 capsules (combination product: its price also pays for other actives); Organics Ocean Organics Ocean Pure Magnesium Glycinate, 90 capsules (combination product: its price also pays for other actives); Goli Goli Dreamy Sleep Gummies, 60 gummies (combination product: its price also pays for other actives); HerbsPro NOW Foods Oregano Oil, 90 Softgels (combination product: its price also pays for other actives); Momentous Momentous 100% Plant Protein, 22 servings (combination product: its price also pays for other actives); Supersmart Pumpkin Seed Oil Supplement (combination product: its price also pays for other actives); HerbsPro NOW Foods UC-II Joint Health Type II Collagen, 60 Caps (combination product: its price also pays for other actives); Renue by Science Renue by Science D3 & K2 liposomal sublingual gel (combination product: its price also pays for other actives); Sports Research Sports Research Vitamin D3 + K2 5000 IU (30 veggie softgels) (combination product: its price also pays for other actives).