Pentadeca arginate
PDA · BPC-157 arginate · BPC-157 arginine salt · pentadecapeptide arginate
Arginine salt of BPC-157 (the same 15-aa gastric peptide), sold as a distinct SKU from BPC-157 acetate. Vendors claim better oral/gastric stability. There is no separate human PK package for the arginate salt - treat identity as BPC-157 with a different counterion. FDA Category 2 applies to the peptide, not the salt name.
Quick answer
What it is: Arginine salt of BPC-157 (the same 15-aa gastric peptide), sold as a distinct SKU from BPC-157 acetate.
Typical research dose: 250-500 mcg/day (injectable) or vendor oral protocols (salt marketed for GI stability)
Research summary, not medical advice.
Use-case scores
- Injury & tissue5/10
- Recovery & sleep4/10
Compound card
- Sequence
- GEPPPGKPADDAGLV (arginine salt)
- Class
- BPC-157 arginine salt (not a new INN)
- Formula
- BPC-157 arginine salt
- Status
- Not FDA-approved · research use
How it works
Pentadeca arginate is BPC-157 as the arginine salt instead of acetate. Sequence is the same pentadecapeptide. Oral-stability claims are formulation marketing. Published animal PK and repair papers are almost entirely BPC-157 acetate or free peptide. FDA Category 2 follows the peptide, not the salt name. If the question is mechanism or PK, read the BPC-157 leaf.
Source: BPC-157: PMID: 30915550. Arginate salt: vendor chemistry, not a separate INN.
Same peptide as BPC-157
If your question is mechanism or Category 2 status, use the BPC-157 leaf. This page exists because vendors sell PDA as a separate SKU (often oral). Do not double-count it as a new INN.
Goal context
Why this leaf exists
Vendors sell PDA as a distinct catalog item, often with oral claims. The sequence is BPC-157. This page is an identity warning, not a second monograph.
Research Use Cases
- ✓Why this leaf exists
Dosing
| Phase | Dose | Frequency | Notes |
|---|---|---|---|
| Injectable (treat as BPC-157) | 250–500 mcg/day | 1–2× daily | Same research range as acetate BPC. |
| Oral SKU | Vendor-dependent | Daily | No consensus human oral bioavailability figure we will print as fact. |
Administration
Pentadeca arginate: oral vs SubQ
- Parenteral identity is BPC-157 with arginine as the counterion. Recon math is legitimate on a cake.
- Separates this SKU from oral-only vendor bottles.
- Not a new INN. Do not double-count animal acetate papers as salt-specific proof.
- FDA Category 2 and WADA S0 still apply.
- This is the catalog reason people search “PDA” instead of BPC-157.
- No BAC water if the SKU is actually a capsule.
- Formulation marketing is not a second evidence base.
- Same peptide, same Category 2 problem, same missing human RCT.
Timeline
Who it is for
BPC-157 salt SKU
LowCatalog differentiation. Evidence is the parent peptide.
Reconstitution
| Vial | Water | Concentration | Example dose |
|---|---|---|---|
| 5 mg (injectable SKU) | 2.0 mL BAC | 2.5 mg/mL | 250 mcg = 0.10 mL = 10 units. Confirm the bottle is injectable, not an oral capsule. |
Change vial size or water volume? Open the reconstitution calculator.
Safety & Considerations
Same caveats as BPC-157: research-only, Category 2, angiogenic theoretical risk. Salt change is not a safety database.
Regulatory & Legal Status
Arginine salt of BPC-157 - same FDA Category 2 peptide, different counterion
Competitive athletes subject to anti-doping controls should not use Pentadeca arginate.
Research Chemical
US Compounding: Not eligible / not available
⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.
Limits of current evidence
- No dedicated human PK package for the arginate salt.
- Animal repair literature is almost entirely acetate or free BPC-157.
- Oral SKUs do not inherit SubQ recon math. Check the label for route.
Verdict
PDA is a salt SKU, not a new peptide. Use it when that is what is in the bottle. Do not treat oral-stability ads as a second PK package. Mechanism, Category 2, and WADA S0 are the BPC-157 story.
Interactions & Contraindications
Same caveats as BPC-157: research-only, Category 2, angiogenic theoretical risk. Salt change is not a safety database.
Pentadeca arginate vs. BPC-157
Canonical comparison: Pentadeca arginate vs BPC-157
| Attribute | Pentadeca arginate | BPC-157 |
|---|---|---|
| Identity | Arginine salt of the same 15-aa peptide | Acetate / free pentadecapeptide in most papers |
| FDA | Category 2 peptide (same molecule) | Category 2 |
| Oral claims | Marketed for GI stability | Also used oral in community; gastric origin is the story |
| PK | Salt-specific human PK unpublished | IV animal PK is minutes - not 4 hours |
Verdict: PDA is BPC-157 with a different counterion. Do not treat it as a new INN.
Frequently Asked Questions
Oral PDA or injectable?▼
Is PDA stronger than BPC-157?▼
Can I put oral PDA in the reconstitution calculator?▼
Does Category 2 still apply?▼
References
- He L, Feng D, Guo H, et al. “Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157 in rats and dogs.” Frontiers in Pharmacology (2022). PMID: 36588717
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