Cognitive & Nootropic

Adamax

Adamantane-Semax · Adamantyl-Semax

Adamantane-modified Semax analog sold as a nasal research spray. Search volume is real; dedicated papers are essentially absent. Treat every half-life and dose number as vendor folklore unless a citation appears. Parent Semax evidence does not automatically transfer to an adamantyl conjugate.

Not FDA-approved - research chemical

Quick answer

What it is: Adamantane-modified Semax analog sold as a nasal research spray.

Typical research dose: 200-600 mcg/day (intranasal; vendor protocols only)

Reconstitution calculator ↓

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team
Last updated: August 2026Evidence: Low
Typical research dose
200-600 mcg/day (intranasal; vendor protocols only)
Frequency
1-2× daily (intranasal)
Half-life
Unknown
Common vials
5 mg / 10 mg
CAS
N/A
Molecular weight
Unverified per lot

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Cognition2.5/10

    Mechanism/in vitro ceiling. No published human PK. Do not inherit Semax’s 5.

Compound card

Sequence
Adamantane-conjugated Semax (vendor structure; confirm COA)
Class
Uncharacterized Semax conjugate
Formula
Adamantyl-Semax (vendor structure; confirm COA)
Status
Not FDA-approved · research use
Dose it
5 mg + 5 mL BAC water → 1 mg/mL · 200 mcg ≈ 20 units (U-100)
Open in calculator

How it works

Adamax is marketed as adamantane-conjugated Semax. Adamantane is a real lipophilicity/stability trick in medicinal chemistry. Transferring Semax’s BDNF papers onto this conjugate without PK is a category error.

We list it because people search it and vendors sell it. Half-life on this page is explicitly unknown.

Source: Parent compound: Semax. Adamax: no indexed human PK as of 2026.

No published human PK

Dose and duration numbers on vendor pages are not citations. If you need evidence, read Semax and treat this as an uncharacterized analog.

Research Use Cases

  • ✓Nootropic analog SKU: Low

Dosing

PhaseDoseFrequencyNotes
Vendor nasal range only200–600 mcg/day1–2× dailyFolklore until a paper exists.

Administration

Route / form
Intranasal
Timing
As sold. Not a label.
Empty stomach?
No - Food timing is not critical.

Timeline

Unknown
Do not invent a Semax-like 15-minute onset as fact.

Who it is for

Nootropic analog SKU

Low

High search, near-zero papers. Listed for identity and recon, not endorsement.

Reconstitution

Vial
5 mg
Diluent
5 mL
Concentration
1 mg/mL
Per Unit (100u syringe)
10 mcg
Dose of 200 mcg = 20 units on a 100-unit insulin syringe

Safety & Considerations

Unknown human safety file. Nasal irritation possible. Adamantane moieties have their own CNS/renal baggage in other drugs - not characterized here.

Regulatory & Legal Status

FDA Status (US)
Research Only

Adamantane-Semax analog. No indexed human PK or approval

WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • No published human PK on this leaf.
  • Dose numbers on vendor pages are not citations.

Verdict

Adamax is a vendor conjugate. Adamantane is real chemistry. Semax papers are not this molecule’s papers.

Interactions & Contraindications

Unknown human safety file. Nasal irritation possible. Adamantane moieties have their own CNS/renal baggage in other drugs - not characterized here.

Adamax vs. Semax

Canonical comparison: Adamax vs Semax

AttributeAdamaxSemax
StructureAdamantane-Semax (vendor)ACTH 4–10 heptapeptide
Human PKNone indexedRussian clinical literature
Evidence levelLowLow–moderate (parent drug in Russia)

Verdict: Adamax is a search term and a SKU. Semax is the molecule with papers. Do not copy Semax onset onto Adamax.

Frequently Asked Questions

Does Adamax last longer than Semax?▼
That is the sales pitch. It is not a published human half-life.

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