Khavinson BioregulatorTarget: BronchiRespiratory

Bronchogen

Ala-Glu-Asp-Leu · AEDL · Bronchial Bioregulator · Бронхоген

Bronchogen is synthetic Ala-Glu-Asp-Leu (AEDL), the bronchial cytogen. Taxorest is the bronchial Cytomax. Chonluten is EDG. Two airway cytogens is manufacturer reality, not a duplicate SKU.

Not FDA-approved - research chemical

Quick answer

What it is: Bronchogen is synthetic Ala-Glu-Asp-Leu (AEDL), the bronchial cytogen.

Class and target: Cytogen (synthetic short peptide) · Bronchi · sequence AEDL

Typical research dose: 1–2 capsules/day (Cytomed) or 1–2 mg SC (research vial)

Reconstitution calculator ↓What it is & the evidence on The Bioregulator Atlas →

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team
Last updated: August 2026Evidence: Low3 peer-reviewed citations
Typical research dose
1–2 capsules/day (Cytomed) or 1–2 mg SC (research vial)
Frequency
1× daily for 10-30 day cycles
Half-life
Short (tetrapeptide)
Common vials
5 mg / 10 mg
CAS
N/A
Molecular weight
504.50 g/mol

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Longevity / aging3.5/10

    Khavinson-school tissue peptide. Single-lab concentration after haircut. Not a Western Phase 3 geroprotector.

  • Immune3/10

    Respiratory aisle in the school. Not an asthma drug.

Compound card

Sequence
AEDL
Class
Khavinson cytogen (AEDL)
Formula
C19H32N6O10
Status
Not FDA-approved · research use
Dose it
5 mg + 2.5 mL BAC water → 2 mg/mL · 1000 mcg ≈ 50 units (U-100)
Open in calculator

How it works

Bronchogen (Ala-Glu-Asp-Leu) is a synthetic tetrapeptide bioregulator targeting bronchial and pulmonary epithelium. It normalizes bronchial epithelial cell gene expression disrupted by chronic inflammation. It promotes mucociliary clearance, regulates secretory IgA production, and downregulates pro-inflammatory cytokines in the respiratory tract. Khavinson studies show improved lung function in patients with chronic bronchitis and COPD.

Source: PMID: 11713572

Khavinson map

Canonical 41
Class
Cytogen (synthetic short peptide)
Organ
Bronchi
Target
Bronchi
System
Respiratory
Sequence
AEDL · Ala-Glu-Asp-Leu
Pair
Taxorest (bronchial Cytomax); Chonluten (EDG) is the other airway cytogen
Бронхоген

Used in bioregulator stacks

Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.

The Khavinson school

Bronchogen is filed here as cytogen (synthetic short peptide), targeting the bronchi. Khavinson's St. Petersburg group moved from organ extracts (Cytamins) to capsule complexes (Cytomaxes) to synthetic short peptides (Cytogens); most of the evidence comes from that one group, with little independent Western replication.

Read the full background, the proposed epigenetic mechanism, the literature limits, and how we count the canonical 41 on the Khavinson bioregulators index.

History of this molecule

AEDL vs EDG is the airway split: Bronchogen more bronchial in the naming, Chonluten lungs-and-bronchi on the poster. Taxorest is the complex for mucosa. Honluten is the extra lung-extract SKU.

This is not albuterol. Mucin, cilia, and epithelial identity are the Khavinson verbs. Keep the inhaler.

Caveats

A defined sequence is not an FDA indication. Bronchi cytogens sit in a Russian experimental-gerontology literature with limited Western replication. “Oral bioavailability because PEPT1” is real peptide-transport biology; it is not proof this SKU treats the organ disease. Gray-market identity is a live problem - HPLC is the only way to know the vial is the sequence on the label.

Full 41-map: Khavinson bioregulators index · Bioregulator stacks

Research Use Cases

  • ✓AEDL identity vs Taxorest vs Chonluten
  • ✓Not a COPD or chronic-bronchitis treatment page

Dosing

PhaseDoseFrequencyNotes
Khavinson Protocol1–2 capsules/day or 1–2 mg SCDaily for 10–30 day courses, 1-2x per yearRespiratory bioregulator course. Often combined with Chonluten or Taxorest.

Administration

Route / form
Two real SKUs: Cytomed oral capsules (swallowed) or a lyophilized research vial reconstituted for subcutaneous injection. Nobody manufactures these as sublingual tablets.
Timing
Capsules: morning, about 30 minutes before meals. Research vial (SubQ): food does not change the injection.
Empty stomach?
Capsules: yes - Swallow on an empty stomach, about 30 minutes before meals. Reconstituted vial (SubQ): food does not change the injection. Cytomed boxes sometimes print “with food” because they are labeled as supplements; the manufacturer user-guide preference is before meals.

Bronchogen: oral vs SubQ

Cytomed oral capsule
Bioavailability
No published human F% for this SKU. PEPT1 is a di-/tripeptide transporter story; a tetrapeptide swallow is a longer, weaker oral argument, not a certificate. Cytomed cytogen capsules are still swallowed.
Dose note
Bronchogen Cytomed cytogen capsules: 1–2 capsules/day, typically 10–30 day courses. No reconstitution. Swallow; do not melt under the tongue. Swallowed with water. Morning, about 30 minutes before meals, is manufacturer user-guide folklore. Cytomed boxes sometimes print “with food” because they are labeled as supplements. That is not a published absorption RCT for this SKU. Pair: Taxorest is the bronchial Cytomax. Chonluten is EDG (the other airway cytogen). Honluten is a lung-extract catalog SKU.
Advantages
  • Official Cytomed cytogen SKU is a swallowed capsule. No BAC water, no syringe.
  • Matches how Cytomed ships the poster line.
  • Nobody manufactures this as a sublingual tablet.
Considerations
  • Capsule milligrams are not 1–2 mg SC. Do not convert a research-vial protocol into capsule counts by arithmetic theater.
  • Empty-stomach timing is user-guide folklore plus PEPT1 logic, not a cited human PK study for this SKU.
  • Bronchogen is AEDL, more bronchial in the naming. Chonluten is EDG, lungs-and-bronchi on the poster. Two airway cytogens is not a duplicate listing.
  • A tetrapeptide swallow is a weaker PEPT1 story than EDG. Still a swallowed capsule, still not a sublingual melt.
Research vial SubQ
Bioavailability
No published human PK curve for this cytogen. Research-chem SubQ is the gray-market route. Class estimate is minutes-to-hours, not a depot ester.
Dose note
Research lyophilized vial: reconstitute with bacteriostatic water, sterile technique, SubQ. Class pattern is about 1–2 mg daily for on the order of 10 days, not a 12-week GLP-1 titration. Food does not change the injection. Do not convert Cytomed capsule counts into vial milligrams. Pair: Taxorest is the bronchial Cytomax. Chonluten is EDG (the other airway cytogen). Honluten is a lung-extract catalog SKU.
Advantages
  • Vial math is checkable if the COA matches the sequence on the label.
  • Food timing is irrelevant for SubQ.
  • Short pulsed courses match how the school used defined synthetics.
Considerations
  • Gray-market identity: HPLC is the only way to know the cake is AEDL (Ala-Glu-Asp-Leu).
  • Not a Western Phase 3. Russian experimental-gerontology literature is real and concentrated.
  • Not a sublingual tablet and not a Cytomax complex.
  • Bronchogen is AEDL, more bronchial in the naming. Chonluten is EDG, lungs-and-bronchi on the poster. Two airway cytogens is not a duplicate listing.
  • Not albuterol. Mucin, cilia, and epithelial identity are the Khavinson verbs. Keep the inhaler.
Recommendation: Two SKUs. Swallow Cytomed Bronchogen capsules (no recon, not sublingual) or BAC-reconstitute a research vial for SubQ at the 1–2 mg / ~10-day class pattern. Food does not change the shot. Pair: Taxorest is the bronchial Cytomax. Chonluten is EDG (the other airway cytogen). Honluten is a lung-extract catalog SKU. Bronchogen is AEDL, more bronchial in the naming. Chonluten is EDG, lungs-and-bronchi on the poster. Two airway cytogens is not a duplicate listing. Russian literature is real; Western Phase 3 is not. Asthma replacement: no.

Timeline

Day 1-10 (course)
Bronchial epithelial gene expression restoration initiated.
Month 3-6
Improved respiratory function and reduced exacerbations with repeat courses.

Who it is for

Respiratory / Lung Health

Low

Bronchial bioregulator. Restores age-suppressed or inflammation-suppressed bronchial gene expression.

Reconstitution

VialWaterConcentrationExample dose
Lyophilized cytogen (if the SKU is a vial)Follow the COA fillDo the mathCapsules skip this step. Cytomax complexes are not this molecule.

Change vial size or water volume? Open the reconstitution calculator.

Safety & Considerations

Research peptide. Extensively used in Russian clinical protocols. Russian clinic history is not a US safety NDA.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • A defined sequence is not an FDA indication.
  • Gray-market identity is a live problem. HPLC beats a blog table.
  • Do not paste a sibling cytogen’s papers onto this SKU.
  • This site will not treat the named organ disease from a peptide page.

Verdict

Bronchogen is the synthetic AEDL cytogen for Bronchi. Khavinson’s group published in this family. That is a concentrated literature, not a Western Phase 3. Capsules and vials are different SKUs.

Interactions & Contraindications

This site will not treat COPD from a peptide page.

Synergies & Common Stacks

+ Taxorest →

Cytogen vs bronchial Cytomax. Not layered respiratory restoration.

Frequently Asked Questions

Bronchogen vs Chonluten vs Taxorest?▼
Bronchogen = AEDL cytogen. Chonluten = EDG cytogen. Taxorest = bronchial Cytomax.
Asthma replacement?▼
No.
Sequence?▼
Ala-Glu-Asp-Leu (AEDL).
Vs Honluten?▼
Honluten is a lung-extract catalog SKU, not this tetrapeptide.
Oral capsule or injection?▼
Two SKUs. Cytomed Bronchogen is a swallowed cytogen capsule (1–2/day, typical 10–30 day courses, morning empty-stomach folklore, no reconstitution, not a sublingual tablet). Research vials are BAC-reconstituted SubQ at about 1–2 mg for on the order of 10 days; food does not change the shot. AEDL bronchi, not Chonluten (EDG), not Taxorest (Cytomax), not Honluten.
What does Bronchogen target?▼
Bronchogen targets the bronchial epithelium. It normalizes mucin production, improves cilia function for airway clearance, and reduces local respiratory inflammation.

References

  1. Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2001). PMID: 11713572
  2. Khavinson VKh, Lin’kova NS, Tarnovskaya SI “Short peptides regulate gene expression.” Bulletin of Experimental Biology and Medicine (2016). PMID: 27909961
  3. Khavinson VKh, Morozov VG “Peptides of pineal gland and thymus prolong human life.” Neuroendocrinology Letters (2003). PMID: 14523363

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