Khavinson BioregulatorTarget: HeartCardiovascular

Chelohart

Heart Extract Bioregulator · Cardiac Cytomax · Челохарт

Chelohart is the Cytomax myocardial complex. Cardiogen is the heart cytogen. Ventfort is vessels. Do not treat “cardio” as one peptide.

Not FDA-approved - research chemical

Quick answer

What it is: Chelohart is the Cytomax myocardial complex.

Class and target: Cytomax (natural peptide complex) · Heart muscle

Typical research dose: 1-2 capsules/day

Dosing details ↓What it is & the evidence on The Bioregulator Atlas →

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team

·Last updated: August 2026·Evidence: Low·3 peer-reviewed citations

Typical research dose

1-2 capsules/day

Frequency

1-2× daily for 10-30 day cycles

Half-life

Mixture (variable)

Common vials

N/A (oral)

CAS

N/A (biological extract)

Molecular weight

Mixture (<10 kDa)

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

Longevity / aging3.5/10
Khavinson-school tissue peptide. Single-lab concentration after haircut. Not a Western Phase 3 geroprotector.

Compound card

Sequence: Heart muscle peptide complex (mixture, not a single CAS)
Class: Khavinson Cytomax capsule complex (Heart muscle)
Formula: Polypeptide extract (Myocardium tissue <10 kDa)
Status: Not FDA-approved · research use

How it works

Chelohart (A-14) is a Cytomax natural polypeptide extract from the cardiac muscle (myocardium) of young calves, delivering a broad-spectrum library of short peptide signals (<10 kDa) targeting human cardiomyocytes. The heart is the most metabolically active organ in the body - by age 60, cardiac output and cardiomyocyte regenerative capacity have measurably declined, leaving the heart more vulnerable to ischemia, oxidative damage, and arrhythmia.

Chelohart's peptides penetrate cardiomyocyte nuclei to relax age-silenced chromatin and reactivate transcription of proteins critical to heart muscle integrity: sarcomere proteins (actin, myosin), mitochondrial respiratory enzymes, and antioxidant defense genes (SOD, catalase). This distinguishes it sharply from simply "protecting" the heart with antioxidants - it works at the gene regulation level.

In the Khavinson system, Chelohart is the natural oral extract counterpart to Cardiogen (the synthesized tetrapeptide Ala-Glu-Asp-Arg). Khavinson's published research from the St. Petersburg Institute (2004) documents normalization of lipid metabolism, improved tolerance to physical load, and reduced cardiac stress markers in elderly patients following polypeptide bioregulator courses. The recommended companion is always Ventfort (A-3, blood vessel extract) to simultaneously support the vascular delivery system alongside the cardiac muscle.

Source: PMID: 11713572

Khavinson map

Canonical 41

Class

Cytomax (natural peptide complex)

Organ

Heart muscle

Target

Heart

System

Cardiovascular

Sequence

Mixture / not a single CAS

Pair

Cardiogen (heart cytogen); Ventfort/Vesugen are vessels, not myocardium

Челохарт

Used in bioregulator stacks

Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.

The Khavinson school

Chelohart is filed here as cytomax (natural peptide complex), targeting the heart muscle. Khavinson's St. Petersburg group moved from organ extracts (Cytamins) to capsule complexes (Cytomaxes) to synthetic short peptides (Cytogens); most of the evidence comes from that one group, with little independent Western replication.

Read the full background, the proposed epigenetic mechanism, the literature limits, and how we count the canonical 41 on the Khavinson bioregulators index.

History of this molecule

Cardiomyocyte identity versus endothelial identity is the whole point of having two aisles. Khavinson’s heart line is muscle cells; the vessel line is the lining. Chelohart + Cardiogen is myocardium. Ventfort + Vesugen is vasculature. SS-31 is a mitochondrial cardiolipin peptide from a completely different American program (Szeto) - do not steal elamipretide papers.

Heart failure remains GDMT. A capsule is not carvedilol.

Caveats

Heart Cytomax is not a US dietary-supplement monograph and not a drug. The tissue-extract model means lot-to-lot composition is a fingerprint, not a single CAS number. Some English-language bottles carry a “V2” label. Vita Peptides, for example, labels its own house line V2 (15 mg per capsule vs 10 mg in V1). No study compares V1 and V2 outcomes, and neither label is the subject of Khavinson’s 1990s papers. Animal-source capsules are inappropriate if the reader has a religious or allergy constraint on the source species. None of this replaces care for the actual organ disease.

Full 41-map: Khavinson bioregulators index · Bioregulator stacks

Research Use Cases

✓Cardiac Cytomax vs Cardiogen
✓Not a cardiovascular treatment page

Dosing

Phase	Dose	Frequency	Notes
Mini-Course / General Preventive (1 box)	2 capsules (20 mg)	Once daily for 10 days, 30 min before meals	Standard Khavinson mini-course (1 pack / 20 caps). Repeat every 6 months. Always pair with Ventfort (A-3, vascular extract) - the heart and vessel health must be addressed together.
Full Monthly Course (ages 40–50)	2 capsules (20 mg)	Twice daily for 30 days (120 caps = 2× 60-cap boxes)	Bi-annual 30-day courses from age 40–45; 3 courses/year after 50. Core cardiovascular stack: Chelohart (A-14) + Ventfort (A-3) + Endoluten (A-8) for cardio-neuroendocrine support.
Intensive / Cardiac Support Protocol	2 capsules (20 mg)	Twice daily, repeated monthly as needed	For post-MI recovery, chronic heart failure support, or significant age-related cardiac decline. Physician supervision required. Consider adding Cardiogen (synthesized tetrapeptide) as an initial 10-day burst before transitioning to oral Chelohart maintenance. Max: 4 caps/day (40 mg).

Administration

Route / form

Oral capsules - swallowed with water. Cytomed Cytomaxes ship as capsules, not sublingual tablets and not lyophilized research vials.

Timing

Morning, with water, about 30 minutes before meals (empty stomach).

Empty stomach?

Yes - Empty stomach - about 30 minutes before meals. Cytomed boxes sometimes print “with food” because they are labeled as supplements; the manufacturer user-guide preference is before meals for absorption.

Chelohart: Not a research vial vs Oral capsule

Not a research vial

Bioavailability

Not applicable. This Cytomax SKU is not sold as a lyophilized research vial. There is no SubQ F% because Cytomed does not ship this complex as a cake.

Dose note

Do not reconstitute Chelohart. No BAC-water chart, no 5 mg vial math, no units-on-a-U-100 conversion. The defined-sequence vial in this aisle is the cytogen pair (Cardiogen (heart cytogen)), a different SKU. There is no pharmaceutical-extract SKU that is this capsule in a syringe.

Advantages

The defined-sequence vial in this aisle is the cytogen pair (Cardiogen (heart cytogen)), a different SKU.
There is no pharmaceutical-extract SKU that is this capsule in a syringe.
Reconstitute Cardiogen if you bought the heart cytogen. A Chelohart cake is a mis-ID. Do not steal Szeto tetrapeptide papers.

Considerations

Chelohart is an oral capsule complex. It is not a 5 mg lyophilized research vial.
Inventing recon math for a zero-mg Cytomax vial is how people inject the wrong product.
Not an official Cytomed sublingual tablet, IM ampoule, or eye drop either.

Oral capsule

Bioavailability

Not quantified in a Western PK study. Official Cytomed form is a swallowed capsule. PEPT1/LAT transport is class biology for short peptides, not an F% for this tissue mixture.

Dose note

Typical Cytomed labeling: 1–2 capsules daily in 10–30 day courses, swallowed with water about 30 minutes before meals (empty stomach). Manufacturer protocol, not an FDA label. Some boxes print “with food” because they are labeled as supplements; the timing copy we use is before meals.

Advantages

Official form for Chelohart: swallow the capsule with water. No reconstitution step and no 5 mg cake.
Heart-muscle Cytomax (Cytomed A-14). Ventfort / Vesugen are vessels, not myocardium. Not SS-31 / elamipretide.
Course-based (10–30 days, a few times a year in manufacturer folklore), not a daily forever drug.

Considerations

Myocardium Cytomax is a peptide mixture / lot fingerprint, not a single CAS. English “V2” bottles are a later commercial layer, not a Khavinson RCT.
Russian school literature is not an FDA organ-disease label.
Third-party lingual SKUs exist in the wild. We do not claim sublingual as the official Cytomed Cytomax form.

Recommendation: Swallow Chelohart as oral capsules with water, about 30 minutes before meals. Myocardial Cytomax complex, not Cardiogen powder, not Ventfort (vessels), and not SS-31. Pair: Cardiogen. Heart failure remains GDMT. Chest pain is an emergency.

Timeline

Days 1–10 (mini-course)

Cardiomyocyte gene expression restoration initiated. Early users may notice reduced exertional fatigue.

Month 1–2

Improved cardiac stamina, normalized lipid metabolism markers in clinical populations.

Month 3–6

Sustained heart muscle integrity support. Reduced cardiac oxidative stress markers per Khavinson 2004 research data.

Who it is for

Cardiac Aging / Heart Muscle Health

Low

Broad-spectrum myocardial bioregulator targeting cardiomyocyte gene expression. Best for preventive maintenance and post-illness recovery.

Cardiovascular Longevity Protocol

Low

Essential component of the Khavinson cardiovascular stack alongside Ventfort (A-3). Addresses the cardiac muscle directly while Ventfort targets the vessel walls.

Safety & Considerations

Natural glandular extract (Cytomax) from bovine cardiac muscle, <10 kDa. No hormones. Meets strict European/Russian veterinary standards. Generally recognized as safe for long-term use.

Regulatory & Legal Status

FDA Status (US)

Research Only

WADA Status (2026)

Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

Cytomax SKUs are oral capsules. Do not run SubQ reconstitution math on a zero-mg vial.
Lot-to-lot composition is a fingerprint, not one sequence.
This site will not treat the named organ disease from a peptide page.
English-language V2 / analog bottles are a later commercial layer, not a Khavinson RCT.

Verdict

Chelohart is a Cytomax capsule complex from Heart muscle. It is not the paired cytogen, not a 5 mg research cake, and not a US supplement monograph. The organ story is in the dossier on this page.

Interactions & Contraindications

Standard Cytomax capsule identity, not a cardiology label.

Synergies & Common Stacks

+ Cardiogen →

Complex vs sequence. Capsules skip vial math.

Frequently Asked Questions

Oral capsule or injection?▼

Chelohart is a Cytomax oral capsule: swallow with water, about 30 minutes before meals. It is not a 5 mg lyophilized research vial and not an official Cytomed sublingual tablet (third-party lingual SKUs exist in the wild). If you want a defined-sequence powder to reconstitute, that is the cytogen pair (Cardiogen), not this complex. Do not run BAC math on a capsule SKU. Ventfort is vessels, not myocardium. This is not SS-31.

Chelohart vs Cardiogen vs Ventfort?▼

Chelohart = heart Cytomax. Cardiogen = heart cytogen. Ventfort = vessel Cytomax. Three SKUs, two tissues.

Is this SS-31?▼

No. SS-31/elamipretide is a Szeto tetrapeptide for cardiolipin. Different sequence, different developer, different trials.

MI treatment?▼

No. Chest pain is an emergency.

Reconstitution?▼

Not Chelohart. Cardiogen vials if you bought the cytogen.

Should I take Chelohart or Cardiogen?▼

They complement each other. Cardiogen is a synthesized tetrapeptide providing a fast, precise signal for cardiac gene activation - ideal for a short 10-day intervention. Chelohart is the natural broad-spectrum extract providing sustained maintenance over 30 days. Many Khavinson protocols use Cardiogen first, then Chelohart for the longer follow-up course.

Should I always take Ventfort with Chelohart?▼

Yes - Vita-Stream and Khavinson both recommend it. Heart health depends on both the muscle (Chelohart) and the vascular delivery system (Ventfort). Using them together provides comprehensive cardiovascular organ system support.

References

Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2001). PMID: 11713572
Khavinson VKh, Lin’kova NS, Tarnovskaya SI “Short peptides regulate gene expression.” Bulletin of Experimental Biology and Medicine (2016). PMID: 27909961
Khavinson VKh, Morozov VG “Peptides of pineal gland and thymus prolong human life.” Neuroendocrinology Letters (2003). PMID: 14523363

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Where to get itOral bioregulator

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Kardium is Vita-Stream's US-made heart bioregulator (Vita Peptides' own house line), a different product from Chelohart. No trial has tested it.

Browse Kardium

Get Chelohart from Vita-Stream, which sells the GARMONIA Cytomax and Cytogen oral capsules. No reconstitution math on a capsule bottle.

Browse Chelohart

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