Botanical

Ginger

Also called Zingiber officinale, ginger root extract, gingerols

By Kymata Labs EditorialMedical review pendingLast reviewed October 11, 2026 · What changed

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Summary

Ginger is best studied for nausea. In 12 pregnancy trials (1,278 women) it eased nausea but not vomiting versus placebo. In a 2024 trial with chemotherapy, standardised ginger improved nausea-related quality of life. In knee osteoarthritis, pain fell modestly, but more people stopped ginger because of side effects.

Top graded outcomes:B evidence grade Nausea in pregnancyB evidence grade Osteoarthritis pain and disabilityC evidence grade Chemotherapy-induced nausea

Key facts

Pregnancy nausea
Less nausea than placebo across 12 trials; vomiting episodes did not change significantly[2]
Chemotherapy
A 103-person trial found better nausea-related quality of life and less delayed nausea with standardised ginger[4]
Osteoarthritis
Small pain and disability improvements; withdrawals from side effects were twice as common[3]
Side effects
Stomach discomfort, heartburn, diarrhoea, mouth and throat irritation[1]
Evidence base
3 graded human outcomes on this page
Last reviewed
October 11, 2026

How it works

ProposedHow ginger eases nausea has not been established; extracts are standardised to gingerols and shogaols, the pungent compounds thought to be active.[4]

What the human research says

Human trials only, one row per outcome. The form column shows what each trial actually tested. Grades follow our evidence-grading policy.

At a glance: strongest evidence per outcome

Evidence at a glance: strongest human evidence per outcome
OutcomeGradeEffectStrongest evidenceRows
NauseaGrade BImprovedMeta-analysis of 12 trials · n = 1,278 · 2014Form tested: Oral ginger (capsules, syrup, powder)2 rows
Joint painGrade BImprovedMeta-analysis of 5 trials · n = 593 · 2015Form tested: Oral ginger extract1 row

Every graded row

Outcome
Grade
Form tested
Sort

Showing 3 of 3 outcomes. Human trials only.

OutcomeEffectGradeBest evidencePMID
Nausea in pregnancyImprovedGrade B

Meta-analysis · n = 1,278 · 2014

Pregnant women with nausea and vomiting in 12 trials

Form: Oral ginger (capsules, syrup, powder) · Dose: Varied; subgroups favoured under 1,500 mg/day · Duration: Varied across trials

Nausea improved versus placebo (MD 1.20); vomiting episodes did not fall significantly (p=0.06). No increased risk of miscarriage, heartburn or drowsiness was found.

24642205 (opens PubMed)Source [2]
Osteoarthritis pain and disabilityImprovedGrade B

Meta-analysis · n = 593 · 2015

Adults with osteoarthritis in 5 placebo-controlled trials

Form: Oral ginger extract · Dose: Varied across trials · Duration: Varied across trials

Pain (SMD −0.30) and disability (SMD −0.22) fell modestly; people on ginger were 2.3 times as likely to stop because of adverse events.

25300574 (opens PubMed)Source [3]
Chemotherapy-induced nauseaImprovedGrade C

RCT · n = 103 · 2024

Chemotherapy-naive adults on moderately to highly emetogenic chemotherapy (Australia)

Form: Standardised ginger root powder · Dose: 4 capsules/day (84 mg gingerols/shogaols) for 5 days per cycle · Duration: 3 chemotherapy cycles

Nausea-related quality of life, delayed nausea and fatigue improved versus placebo; delayed vomiting at cycle 3 was 2% vs 23%.

37699474 (opens PubMed)Source [4]

Forms

FormElemental %Absorption (human data)GI toleranceStudied for
Dried ginger root powderVariesNot applicable (whole compound or extract; no elemental fraction)No head-to-head human absorption data in the sources cited here.Stomach discomfort and heartburn are the usual complaints.[1]Most pregnancy trials
Extract standardised to gingerols/shogaolsVariesNot applicable (whole compound or extract; no elemental fraction)No head-to-head human absorption data in the sources cited here.No separate tolerance data beyond the trials cited here.Chemotherapy nausea trial (84 mg active gingerols/shogaols per day)

Studied doses

Doses studied in human trials ranged from a standardised extract supplying 84 mg of gingerols and shogaols per day (chemotherapy nausea) to about 1,500 mg of ginger per day in pregnancy trials, where doses below 1,500 mg looked better for nausea.[2][4]

These are amounts used in research, not personal advice. Your clinician or pharmacist can say what fits you.

Interactions

Published interactions only: each row cites a source. No row means none was found in our sources, not that a combination is safe.

None found in our sources.

Who should be careful

Pregnancy
NCCIH says ginger may be safe for pregnancy nausea but advises talking with your provider first.[1]
Breastfeeding
Little is known about safety while breastfeeding.[1]

Talk to your pharmacist or clinician before starting a supplement, especially if you take prescription medicines.

Frequently asked questions

Does ginger help morning sickness?

Across 12 trials it reduced nausea more than placebo, but not vomiting; NCCIH advises checking with your provider in pregnancy.[2][1]

Does ginger help chemotherapy nausea?

A 103-person trial found less delayed nausea alongside standard anti-sickness drugs; NCCIH calls the overall evidence uncertain.[4][1]

Does ginger help arthritis pain?

Pain fell slightly in pooled trials, but more people stopped ginger because of side effects.[3]

What are the side effects?

Stomach discomfort, heartburn, diarrhoea and mouth or throat irritation.[1]

Sources

  1. [1]Ginger. National Center for Complementary and Integrative Health (NCCIH), 2025. fact-sheet
  2. [2]A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting.. Nutr J, 2014. meta-analysis PMID 24642205
  3. [3]Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials.. Osteoarthritis Cartilage, 2015. meta-analysis PMID 25300574
  4. [4]Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial.. J Acad Nutr Diet, 2024. RCT PMID 37699474

What changed

  1. October 11, 2026 · all · new page (encyclopedia expansion, A–L)First draft. Every PMID checked against NCBI E-utilities (title, journal and year taken from the PubMed record) and each evidence row written from its PubMed abstract; self-reviewed in a separate adversarial pass.Writer: Kymata Labs Editorial · No credentialed reviewer yet

How we write, grade and correct these pages: editorial and evidence policy.

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