Khavinson BioregulatorTarget: TestesReproductive

Testagen

Testes Bioregulator Tripeptide · Testicular Peptide · Тестаген

Testagen is the testicular cytogen on the NPCRIZ list. Testoluten is the Cytomax complex. This is not testosterone cypionate, not hCG, and not a published one-letter sequence as clean as AEDG. English tables disagree on the residue string - demand a COA.

Not FDA-approved - research chemical

Quick answer

What it is: Testagen is the testicular cytogen on the NPCRIZ list.

Class and target: Cytogen (synthetic short peptide) · Testes

Typical research dose: 1–2 capsules/day (Cytomed) or 1–2 mg SC (research vial)

Reconstitution calculator ↓What it is & the evidence on The Bioregulator Atlas →

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team
Last updated: August 2026Evidence: Low3 peer-reviewed citations
Typical research dose
1–2 capsules/day (Cytomed) or 1–2 mg SC (research vial)
Frequency
1× daily for 10-30 day cycles
Half-life
Short (tetrapeptide)
Common vials
5 mg / 10 mg
CAS
N/A
Molecular weight
419.39 g/mol

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Longevity / aging3.5/10

    Khavinson-school tissue peptide. Single-lab concentration after haircut. Not a Western Phase 3 geroprotector.

Compound card

Sequence
Confirm COA (vendor tables conflict; not a clean AEDG-style code)
Class
Khavinson cytogen (testes; sequence disputed)
Formula
C15H25N5O9
Status
Not FDA-approved · research use
Dose it
5 mg + 2.5 mL BAC water → 2 mg/mL · 1000 mcg ≈ 50 units (U-100)
Open in calculator

How it works

Testagen (Lys-Glu-Asp-Gly) is a tetrapeptide bioregulator targeting testicular tissue. It promotes the restoration of testicular cell gene expression, supporting Leydig cell function (testosterone production) and spermatogenesis. It is used in Khavinson protocols to address age-related decline in male endocrine function, restoring the body's natural rhythm rather than replacing exogenous hormones.

Source: PMID: 11713572

Khavinson map

Canonical 41
Class
Cytogen (synthetic short peptide)
Organ
Testes
Target
Testes
System
Reproductive
Sequence
Mixture / not a single CAS
Pair
Testoluten (testicular Cytomax)
Тестаген

Used in bioregulator stacks

Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.

The Khavinson school

Testagen is filed here as cytogen (synthetic short peptide), targeting the testes. Khavinson's St. Petersburg group moved from organ extracts (Cytamins) to capsule complexes (Cytomaxes) to synthetic short peptides (Cytogens); most of the evidence comes from that one group, with little independent Western replication.

Read the full background, the proposed epigenetic mechanism, the literature limits, and how we count the canonical 41 on the Khavinson bioregulators index.

History of this molecule

Male-optimization Twitter wants Testagen to be oral TRT. It is a Khavinson organ-identity peptide for testicular tissue. The complex is Testoluten. Libidon/Prostamax are prostate. Mixing glands because both are “male” is how PSA and fertility get ignored.

We do not print a confident tetrapeptide code here because our own database listed it as a tripeptide without residues, and vendor tables conflict. Identity first, fantasy sequence never.

Caveats

A defined sequence is not an FDA indication. Testis cytogens sit in a Russian experimental-gerontology literature with limited Western replication. “Oral bioavailability because PEPT1” is real peptide-transport biology; it is not proof this SKU treats the organ disease. Gray-market identity is a live problem - HPLC is the only way to know the vial is the sequence on the label.

Full 41-map: Khavinson bioregulators index · Bioregulator stacks

Research Use Cases

  • ✓Testicular-aisle cytogen vs Testoluten (confirm sequence on the COA)
  • ✓Not a testosterone-optimization protocol

Dosing

PhaseDoseFrequencyNotes
Khavinson Protocol1–2 capsules/day or 1–2 mg SCDaily for 10–30 day courses, 1-2x per yearTesticular bioregulator. Usually paired with Endoluten (pineal) and Libidon (prostate) for male health.

Administration

Route / form
Two real SKUs: Cytomed oral capsules (swallowed) or a lyophilized research vial reconstituted for subcutaneous injection. Nobody manufactures these as sublingual tablets.
Timing
Capsules: morning, about 30 minutes before meals. Research vial (SubQ): food does not change the injection.
Empty stomach?
Capsules: yes - Swallow on an empty stomach, about 30 minutes before meals. Reconstituted vial (SubQ): food does not change the injection. Cytomed boxes sometimes print “with food” because they are labeled as supplements; the manufacturer user-guide preference is before meals.

Testagen: oral vs SubQ

Cytomed oral capsule
Bioavailability
No published human F% for this SKU. Short-peptide oral absorption is a PEPT1/LAT conversation in the school, not an FDA bioavailability table. Cytomed cytogen capsules are swallowed.
Dose note
Testagen Cytomed cytogen capsules: 1–2 capsules/day, typically 10–30 day courses. No reconstitution. Swallow; do not melt under the tongue. Swallowed with water. Morning, about 30 minutes before meals, is manufacturer user-guide folklore. Cytomed boxes sometimes print “with food” because they are labeled as supplements. That is not a published absorption RCT for this SKU. Pair: Testoluten is the testicular Cytomax. Libidon and Prostamax are prostate. Mixing glands because both are “male” is how PSA and fertility get ignored.
Advantages
  • Official Cytomed cytogen SKU is a swallowed capsule. No BAC water, no syringe.
  • Matches how Cytomed ships the poster line.
  • Nobody manufactures this as a sublingual tablet.
Considerations
  • Capsule milligrams are not 1–2 mg SC. Do not convert a research-vial protocol into capsule counts by arithmetic theater.
  • Empty-stomach timing is user-guide folklore plus PEPT1 logic, not a cited human PK study for this SKU.
  • Testagen is the testicular cytogen. It is not testosterone cypionate, not hCG, and not a published one-letter sequence as clean as AEDG.
  • Male-optimization Twitter wants this to be oral TRT. It is a Khavinson organ-identity peptide. Get morning labs if total T is the actual question.
Research vial SubQ
Bioavailability
No published human PK curve for this cytogen. Research-chem SubQ is the gray-market route. Class estimate is minutes-to-hours, not a depot ester.
Dose note
Research lyophilized vial: reconstitute with bacteriostatic water, sterile technique, SubQ. Class pattern is about 1–2 mg daily for on the order of 10 days, not a 12-week GLP-1 titration. Food does not change the injection. Do not convert Cytomed capsule counts into vial milligrams. Pair: Testoluten is the testicular Cytomax. Libidon and Prostamax are prostate. Mixing glands because both are “male” is how PSA and fertility get ignored.
Advantages
  • Vial math is checkable if the COA matches the sequence on the label.
  • Food timing is irrelevant for SubQ.
  • Short pulsed courses match how the school used defined synthetics.
Considerations
  • Gray-market identity: HPLC is the only way to know the cake is contested in English catalogs (confirm COA; do not steal AEDG).
  • Not a Western Phase 3. Russian experimental-gerontology literature is real and concentrated.
  • Not a sublingual tablet and not a Cytomax complex.
  • Testagen is the testicular cytogen. It is not testosterone cypionate, not hCG, and not a published one-letter sequence as clean as AEDG.
  • Vendor tables conflict on the residue string. Identity first, fantasy sequence never. HPLC beats a blog table.
Recommendation: Two SKUs. Swallow Cytomed Testagen capsules (no recon, not sublingual) or BAC-reconstitute a research vial for SubQ at the 1–2 mg / ~10-day class pattern. Food does not change the shot. Pair: Testoluten is the testicular Cytomax. Libidon and Prostamax are prostate. Mixing glands because both are “male” is how PSA and fertility get ignored. Testagen is the testicular cytogen. It is not testosterone cypionate, not hCG, and not a published one-letter sequence as clean as AEDG. Russian literature is real; Western Phase 3 is not. Not a labeled T-trial. TRAVERSE is not a Testagen paper.

Timeline

Day 1-10 (course)
Testicular gene expression restoration initiated.
Month 3-6
Improved endogenous testosterone markers and vitality.

Who it is for

Male Endocrine Aging

Low

Testicular bioregulator. Restores age-suppressed testicular gene expression without shutting down HPTA.

Reconstitution

VialWaterConcentrationExample dose
Lyophilized cytogen (if the SKU is a vial)Follow the COA fillDo the mathCapsules skip this step. Cytomax complexes are not this molecule.

Change vial size or water volume? Open the reconstitution calculator.

Safety & Considerations

Research peptide. Extensively used in Russian clinical protocols. Does NOT shut down natural testosterone production like TRT.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • A defined sequence is not an FDA indication.
  • Gray-market identity is a live problem. HPLC beats a blog table.
  • Do not paste a sibling cytogen’s papers onto this SKU.
  • This site will not treat the named organ disease from a peptide page.

Verdict

Testagen is the synthetic short peptide cytogen for Testes. Khavinson’s group published in this family. That is a concentrated literature, not a Western Phase 3. Capsules and vials are different SKUs.

Interactions & Contraindications

Not exogenous testosterone. Confirm identity before stacking names.

Synergies & Common Stacks

+ Testoluten →

Cytogen vs Cytomax. Not TRT.

Frequently Asked Questions

Testagen vs Testoluten vs testosterone?▼
Testagen = testicular cytogen. Testoluten = testis Cytomax. Testosterone ester = HRT. Different tools.
Sequence?▼
Contested in English catalogs. Do not trust a random “KEDG” table without HPLC. Epitalon is AEDG - do not steal that code.
Vs Libidon?▼
Libidon is prostate. Testagen is testis.
Will total T double?▼
Not a labeled effect. Get morning labs if that is the actual question.
Oral capsule or injection?▼
Two SKUs. Cytomed Testagen is a swallowed cytogen capsule (1–2/day, typical 10–30 day courses, morning empty-stomach folklore, no reconstitution, not a sublingual tablet). Research vials are BAC-reconstituted SubQ at about 1–2 mg for on the order of 10 days; food does not change the shot. Testicular cytogen, not TRT, not Testoluten (Cytomax), not prostate (Libidon/Prostamax).
Is Testagen a substitute for TRT?▼
No. TRT replaces testosterone with an exogenous source, which shuts down natural testicular production. Testagen is a bioregulator that signals your testes to restore their own natural production capacity, addressing aging at the cellular level without causing suppression.

References

  1. Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2001). PMID: 11713572
  2. Khavinson VKh, Lin’kova NS, Tarnovskaya SI “Short peptides regulate gene expression.” Bulletin of Experimental Biology and Medicine (2016). PMID: 27909961
  3. Khavinson VKh, Morozov VG “Peptides of pineal gland and thymus prolong human life.” Neuroendocrinology Letters (2003). PMID: 14523363

📚 Related Articles

Epitalon: The Science of Telomerase Activation, Khavinson's Legacy, and Longevity Peptides
14 min read • Longevity
Where to get itOral bioregulator

Affiliate links: we earn a commission if you buy, at no extra cost to you.

Testovive is Vita-Stream's US-made testes bioregulator (Vita Peptides' own house line), a different product from Testagen. No trial has tested it.

Browse Testovive

Use code KymataLabs at checkout

See all sources and our full review

← Back to Peptide Library·Bioregulator stacks