Stevia (steviol glycosides) and gut bacteria

What 2 graded rows on stevia (steviol glycosides) agree on for gut bacteria, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Stevia (steviol glycosides) page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Stevia (steviol glycosides) page, with its PubMed record.

Supplement

Stevia (steviol glycosides) Choose another

2 rows · 179 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade C, is a randomized trial of 120 people (2022) and reported mixed results.

The rows run from 59 to 120 people, published from 2022 to 2024: 2 single studies.

1 no difference · 1 mixed

Grade CGut microbiome and short-chain fatty acids vs a sucrose drink · No difference
RCT · n 59 · 2024 · Healthy adults, mean age 31 (36 women, 23 men)
16 oz drink daily · 4 weeks, then 4-week washout
No differences in the gut microbiome at any level or in faecal short-chain fatty acids; fasting glucose, insulin, lipids and blood pressure did not differ. BMI rose 0.3 kg/m² with sucrose compared with stevia.
Row on the Stevia (steviol glycosides) page · PubMed 38408729 (opens PubMed)
Grade CGlucose tolerance and gut microbes after 2 weeks of sweetener sachets · Mixed
RCT · n 120 · 2022 · Healthy adults randomized to saccharin, sucralose, aspartame, stevia, glucose vehicle or no supplement
Sachets daily, below the acceptable daily intake · 2 weeks
Each sweetener, stevia included, changed stool and oral microbes and plasma metabolites. Saccharin and sucralose significantly impaired glucose responses; stevia was not reported to.
Row on the Stevia (steviol glycosides) page · PubMed 35987213 (opens PubMed)