Stevia (steviol glycosides) and blood pressure
What 4 graded rows on stevia (steviol glycosides) agree on for blood pressure, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Stevia (steviol glycosides) page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Stevia (steviol glycosides) page, with its PubMed record.
Your question
Stevia (steviol glycosides) and blood pressure
4 rows · 1,130 peopleSplit. 2 rows found an improvement, 1 found no difference and 1 had mixed results.
- CGrade C× 3
- ∅No effect× 1
- Rows
- 4
- Trials
- 12
- People
- 1,130
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade C, is a meta-analysis of 756 people (2015) and reported mixed results. 1 row is graded No effect, our grade for adequately powered trials that found no effect.
The 2 rows that found an improvement ran longer (12 months to 2 years) than the row that found no difference (4 weeks).
Only the 2 rows that found an improvement name men in their population.
The row that found no difference is newer (2008) than the 2 rows that found an improvement (2000 to 2003).
1 row with mixed results is left out of this comparison.
The rows
2 improved · 1 no difference · 1 mixed- CGrade CBlood pressure in mild hypertension (2 years) · Improved
RCT · n 168 · 2003 · Chinese adults aged 20 to 75 with mild essential hypertension (174 enrolled, 87 men and 87 women)
500 mg three times a day (1,500 mg/day) · 2 years
Systolic pressure fell from 150 to 140 mm Hg and diastolic from 95 to 89 mm Hg with stevioside, significantly more than placebo; the effect began about a week after starting. Body mass index, blood tests and adverse events did not differ from placebo.
Row on the Stevia (steviol glycosides) page · PubMed 14693305 (opens PubMed)
- CGrade CBlood pressure in hypertension (1 year) · Improved
RCT · n 106 · 2000 · Chinese adults aged 28 to 75 with diastolic pressure 95 to 110 mm Hg
250 mg three times a day (750 mg/day) · 1 year
After 3 months, systolic pressure fell from 166.0 to 152.6 mm Hg and diastolic from 104.7 to 90.3 mm Hg, and the effect persisted for the year. Lipids and glucose did not change and no significant adverse effects were seen.
Row on the Stevia (steviol glycosides) page · PubMed 10971305 (opens PubMed)
- ∅No effectBlood pressure in people with normal or low-normal pressure · No difference
RCT · n 100 · 2008 · Healthy adults aged 18 to 73, mostly women, with resting pressure around 110/70 mm Hg
1,000 mg/day · 4 weeks
Rebaudioside A did not change resting blood pressure, mean arterial pressure, heart rate or 24-hour ambulatory pressure compared with placebo.
Row on the Stevia (steviol glycosides) page · PubMed 18555574 (opens PubMed)
- CGrade CBlood pressure, fasting glucose and lipids (pooled) · Mixed
Meta-analysis, 9 studies · n 756 · 2015 · Participants of 9 randomized trials, most at high cardiovascular risk
As given in each included trial · Varied by trial
Systolic pressure did not differ significantly from placebo (−2.98 mm Hg, 95% CI −6.23 to 0.27); diastolic pressure and fasting glucose fell significantly, with no effect on lipids. Rebaudioside A had no significant effect on blood pressure or other risk factors. Heterogeneity was significant.
Row on the Stevia (steviol glycosides) page · PubMed 25412840 (opens PubMed)