Stevia (steviol glycosides) and appetite

What 3 graded rows on stevia (steviol glycosides) agree on for appetite, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Stevia (steviol glycosides) page, with its PubMed record.

Your question

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Stevia (steviol glycosides) and appetite

3 rows · 478 people

Mostly no difference: 2 of 3 rows, and most of the people. 1 found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • Grade D× 2
Rows
3
Trials
13
People
478
Pooled reviews may count some twice

Where they differ

From the rows
Trial sizeStudy designWho was studiedGrade

The best-graded row, grade C, is a meta-analysis of 428 people (2025) and found no difference.

The 2 rows that found no difference were larger: a median of 229 people, against 20 people for the row that found an improvement.

Only the 2 rows that found no difference include pooled reviews of several trials (1 of 2); the row that found an improvement is a single study.

Only the 2 rows that found no difference name men in their population. Only the row that found an improvement names women in its population.

The best grade is C among the rows that found no difference, and D among the row that found an improvement.

The rows

1 improved · 2 no difference
  1. Grade CAppetite scores (pooled) · No difference

    Meta-analysis, 11 studies · n 428 · 2025 · Adults in 11 clinical trials

    As given in each trial · Varied by trial

    Stevia had no significant effect on any appetite score (very low to moderate certainty); too few trials reported energy intake to pool.

    Row on the Stevia (steviol glycosides) page · PubMed 39887829 (opens PubMed)

  2. Grade DDaily energy intake and glucose after a sweetened drink · No difference

    Crossover RCT · n 30 · 2017 · Healthy men

    One drink mid-morning · Single test days

    People ate more at lunch after the no-calorie drinks, so the energy saved was fully made up and total daily intake did not differ. Total 3-hour glucose and insulin areas did not differ between the four drinks.

    Row on the Stevia (steviol glycosides) page · PubMed 27956737 (opens PubMed)

  3. Grade DAppetite and total energy intake at lunch after a stevia drink · Improved

    Crossover RCT · n 20 · 2020 · Healthy adults, mean age 27, 55% women

    One 330 mL drink before lunch · Single test visits

    Total energy (drink plus lunch) was lower after the stevia drink (727 kcal) than after water (832 kcal, P = 0.013). Blood glucose after stevia was similar to water and lower than after the caloric drinks.

    Row on the Stevia (steviol glycosides) page · PubMed 32125421 (opens PubMed)

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