L. rhamnosus GR-1 and L. reuteri RC-14 and bacterial vaginosis
What 5 graded rows on l. rhamnosus gr-1 and l. reuteri rc-14 agree on for bacterial vaginosis, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the L. rhamnosus GR-1 and L. reuteri RC-14 page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the L. rhamnosus GR-1 and L. reuteri RC-14 page, with its PubMed record.
Your question
L. rhamnosus GR-1 and L. reuteri RC-14 and bacterial vaginosis
5 rows · 924 peopleSplit. 3 rows found an improvement, 1 found no difference and 1 had mixed results.
- CGrade C× 3
- DGrade D× 1
- ∅No effect× 1
- Rows
- 5
- Trials
- 5
- People
- 924
Where they differ
From the rowsThe best-graded row, grade C, is a randomized trial of 544 people (2013) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.
The row that found no difference is newer (2021) than the 3 rows that found an improvement (2006 to 2013).
1 row with mixed results is left out of this comparison.
The rows
3 improved · 1 no difference · 1 mixed- CGrade CReturn to balanced vaginal flora (oral probiotic alone) · Improved
RCT · n 544 · 2013 · 544 Croatian women diagnosed with vaginal infection in a bacterial vaginosis trial (395 probiotic, 149 placebo)
1 capsule a day · 6 weeks, follow-up to 12 weeks
Balanced flora returned in 61.5% on probiotic vs 26.9% on placebo (p<0.001); at 12 weeks, 51.1% vs 20.8% still had normal flora (p<0.001).
Row on the L. rhamnosus GR-1 and L. reuteri RC-14 page · PubMed 23395559 (opens PubMed)
- CGrade CBacterial vaginosis clearance with metronidazole · Improved
RCT · n 125 · 2006 · 125 premenopausal Nigerian women with bacterial vaginosis; 106 returned at day 30
1 billion CFU of each strain twice daily (metronidazole 500 mg twice daily on days 1 to 7) · 30 days
88% were cured with antibiotic plus probiotic vs 40% with antibiotic plus placebo (p<0.001); high vaginal lactobacilli counts in 96% vs 53%.
Row on the L. rhamnosus GR-1 and L. reuteri RC-14 page · PubMed 16697231 (opens PubMed)
- CGrade CBacterial vaginosis clearance with tinidazole · Improved
RCT · n 64 · 2009 · 64 Brazilian women with bacterial vaginosis
2 capsules every morning (tinidazole 2 g once) · 4 weeks
Cure rate 87.5% with probiotic vs 50.0% with placebo (p = 0.001); normal Nugent-score flora in 75.0% vs 34.4% (p = 0.011).
Row on the L. rhamnosus GR-1 and L. reuteri RC-14 page · PubMed 19295645 (opens PubMed)
- ∅No effectBacterial vaginosis clearance with vaginal metronidazole · No difference
RCT · n 126 · 2021 · 126 Chinese women with bacterial vaginosis
Oral probiotic for 30 days (metronidazole suppositories for 7 days) · 30 days, follow-up to 90 days
30-day cure 57.69% with probiotic vs 59.57% with metronidazole alone; 90-day cure 36.54% vs 48.94% (p = 0.213); probiotic strains were rarely detected in vaginal or faecal samples.
Row on the L. rhamnosus GR-1 and L. reuteri RC-14 page · PubMed 34295831 (opens PubMed)
- DGrade DBacterial vaginosis in women with HIV · Mixed
RCT · n 65 · 2010 · 65 women with HIV and abnormal vaginal flora (Nugent score 4 to 10) in Tanzania
Daily (CFU not stated in this abstract); women with BV also had metronidazole 400 mg twice daily for 10 days · 6 months
Adding the probiotic did not raise the BV cure rate with metronidazole. In women with intermediate flora it raised the chance of a healthy vaginal pH (odds ratio 3.8; P=0.02) and tended to raise the chance of normal flora (odds ratio 2.4; P=0.1).
Row on the L. rhamnosus GR-1 and L. reuteri RC-14 page · PubMed 20801446 (opens PubMed)