Glutathione (oral) and blood sugar

What 2 graded rows on glutathione (oral) agree on for blood sugar, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Glutathione (oral) page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Glutathione (oral) page, with its PubMed record.

Supplement

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2 rows · 226 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade C, is a randomized trial of 206 people (2022) and reported mixed results.

The rows run from 20 to 206 people, published from 2021 to 2022: 2 single studies.

1 improved · 1 mixed

Grade DInsulin sensitivity in obesity, with or without type 2 diabetes · Improved
RCT · n 20 · 2021 · Men with obesity, 10 of them with type 2 diabetes
1,000 mg/day · 3 weeks
Whole-body insulin sensitivity (clamp test) rose significantly in the glutathione group. Muscle glutathione rose about 19% (numerically), and oxidative-stress markers did not change.
Row on the Glutathione (oral) page · PubMed 33740389 (opens PubMed)
Grade CHbA1c and blood glutathione in type 2 diabetes · Mixed
RCT · n 206 · 2022 · Adults with type 2 diabetes on diabetes medicines
500 mg/day · 6 months
Blood glutathione rose and the DNA-damage marker 8-OHdG fell within 3 months in the glutathione group. Overall HbA1c fell about as much as with diabetes medicines alone; in a post hoc subgroup over 55, HbA1c fell more with glutathione (Cohen's d −0.41).
Row on the Glutathione (oral) page · PubMed 35624890 (opens PubMed)