CoQ10 (ubiquinol vs ubiquinone) and blood pressure
What 2 graded rows on coq10 (ubiquinol vs ubiquinone) agree on for blood pressure, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the CoQ10 (ubiquinol vs ubiquinone) page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the CoQ10 (ubiquinol vs ubiquinone) page, with its PubMed record.
Your question
CoQ10 (ubiquinol vs ubiquinone) and blood pressure
2 rows · 1,881 peopleSplit. 1 row found an improvement and 1 found no difference.
- BGrade B× 1
- CGrade C× 1
- Rows
- 2
- Trials
- 28
- People
- 1,881
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade B, is a meta-analysis of 1,831 people (2022) and found an improvement.
The row that found an improvement was larger: 1,831 people, against 50 people for the row that found no difference.
The row that found an improvement is newer (2022) than the row that found no difference (2016).
The best grade is B among the row that found an improvement, and C among the row that found no difference.
The rows
1 improved · 1 no difference- BGrade BSystolic blood pressure in cardiometabolic disease · Improved
Meta-analysis, 26 studies · n 1,831 · 2022 · Adults with cardiometabolic disorders (such as diabetes and dyslipidemia) in 26 randomized trials
Varied; about 100 to 200 mg/day gave the largest systolic fall in the dose-response analysis · Varied across trials
Systolic blood pressure fell by 4.77 mm Hg (95% CI −6.57 to −2.97; moderate certainty); the evidence for diastolic pressure was low certainty. Falls were larger in diabetes and dyslipidemia and in trials longer than 12 weeks.
Row on the CoQ10 (ubiquinol vs ubiquinone) page · PubMed 36130103 (opens PubMed)
- CGrade CBlood pressure · No difference
Meta-analysis, 2 studies · n 50 · 2016 · 2 double-blind RCTs in adults with primary hypertension
Varied across trials · At least 3 weeks
No significant change in systolic (-3.68 mm Hg) or diastolic (-2.03 mm Hg) blood pressure; authors judged the evidence moderate quality for no clinically significant effect.
Row on the CoQ10 (ubiquinol vs ubiquinone) page · PubMed 26935713 (opens PubMed)