Chanca piedra (Phyllanthus niruri, gale of the wind) and kidney stones

What 3 graded rows on chanca piedra (phyllanthus niruri, gale of the wind) agree on for kidney stones, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Chanca piedra (Phyllanthus niruri, gale of the wind) page, with its PubMed record.

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Chanca piedra (Phyllanthus niruri, gale of the wind) and kidney stones

3 rows · 275 people

Split. 1 row found an improvement and 2 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
  • Grade D× 1
Rows
3
Trials
3
People
275

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 150 people (2006) and reported mixed results.

The rows run from 56 to 150 people, published from 2004 to 2018: 3 single studies.

The rows

1 improved · 2 mixed
  1. Grade DUrine chemistry and stone elimination · Improved

    Open-label trial · n 56 · 2018 · Brazilian adults with kidney stones under 10 mm

    Not stated in the abstract · 12 weeks

    Urinary potassium rose; in people with high urinary oxalate, oxalate fell from 59.0 to 28.8 mg/24 h, and in those with high uric acid, uric acid fell. Serum measures were unchanged, and the authors report stone elimination.

    Row on the Chanca piedra (Phyllanthus niruri, gale of the wind) page · PubMed 29617079 (opens PubMed)

  2. Grade CStone clearance after shock-wave lithotripsy · Mixed

    RCT · n 150 · 2006 · Italian adults with calcium oxalate kidney stones up to 25 mm treated with shock-wave lithotripsy

    2 g/day · At least 3 months (follow-up 180 days)

    Stone-free rate at 180 days was 93.5% with P. niruri vs 83.3% in untreated controls (p = 0.48 overall); the authors report a significant benefit for lower-pole (lower caliceal) stones. Re-treatment was needed in 39.7% vs 43.3%. No side effects were recorded.

    Row on the Chanca piedra (Phyllanthus niruri, gale of the wind) page · PubMed 16890682 (opens PubMed)

  3. Grade CUrine chemistry and stone passage in calcium stone formers · Mixed

    RCT · n 69 · 2004 · Brazilian adults who form calcium kidney stones

    450 mg capsules (frequency abbreviated 'td' in the abstract) · 3 months

    No overall change in urinary calcium, uric acid, citrate, oxalate or other measures and no difference in stone passage or pain versus placebo; in the subgroup with high urinary calcium, urinary calcium fell.

    Row on the Chanca piedra (Phyllanthus niruri, gale of the wind) page · PubMed 15221244 (opens PubMed)

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