Bacillus coagulans (spore-forming probiotic) and constipation

What 2 graded rows on bacillus coagulans (spore-forming probiotic) agree on for constipation, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Bacillus coagulans (spore-forming probiotic) page, with its PubMed record.

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Bacillus coagulans (spore-forming probiotic) and constipation

2 rows · 244 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
Rows
2
Trials
2
People
244

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 144 people (2025) and found an improvement.

The rows run from 100 to 144 people, published from 2020 to 2025: 2 single studies.

The rows

2 improved
  1. Grade CBowel movement frequency and stool consistency in healthy adults · Improved

    RCT · n 144 · 2025 · Healthy adults with 3 to fewer than 7 spontaneous bowel movements a week during a 2-week run-in

    2 billion CFU daily · 4 weeks

    Bowel movement frequency rose versus placebo (P = 0.037) and stool consistency improved (P = 0.018), driven by fewer hard stools (P = 0.001). GI symptoms, quality of life and gut microbiota did not change. Safe and well tolerated.

    Row on the Bacillus coagulans (spore-forming probiotic) page · PubMed 40456531 (opens PubMed)

  2. Grade CBowel movements in functional constipation · Improved

    RCT · n 100 · 2020 · Adults with functional constipation

    2 billion CFU once daily · 4 weeks

    Bowel movements increased significantly versus placebo (p<0.001); 98% vs 74% reached normal stool consistency, with less incomplete evacuation, painful defecation and abdominal pain.

    Row on the Bacillus coagulans (spore-forming probiotic) page · PubMed 30911991 (opens PubMed)

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