Akkermansia muciniphila and weight

What 2 graded rows on akkermansia muciniphila agree on for weight, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Akkermansia muciniphila page, with its PubMed record.

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Akkermansia muciniphila and weight

2 rows · 156 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
2
People
156

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 90 people (2026) and found an improvement.

The rows run from 66 to 90 people, published from 2025 to 2026: 2 single studies.

The rows

2 improved
  1. Grade CWeight regain after a low-energy diet · Improved

    RCT · n 90 · 2026 · Adults with overweight or obesity who lost at least 8% of body weight on an 8-week low-energy diet

    Daily (amount not stated in the abstract) · 24 weeks

    Weight regain was 1.2 kg versus 3.2 kg on placebo (P = 0.012), and net loss from baseline was 3.1 kg greater. No serious treatment-related adverse events.

    Row on the Akkermansia muciniphila page · PubMed 42120725 (opens PubMed)

  2. Grade DWaist, body fat and liver enzymes in overweight (postbiotic yogurt) · Improved

    RCT · n 66 · 2025 · 66 adults with overweight or obesity in Iran, 22 per arm (Akkermansia yogurt, L. rhamnosus yogurt, plain low-fat yogurt)

    Daily yogurt (cell count not stated in the abstract) · 8 weeks

    Compared with plain yogurt, the Akkermansia yogurt lowered waist circumference (P = 0.003), waist-to-height ratio, body fat percentage (P = 0.032), AST (P = 0.045) and appetite scores; the L. rhamnosus yogurt showed no benefit.

    Row on the Akkermansia muciniphila page · PubMed 40451504 (opens PubMed)

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