Akkermansia muciniphila and blood sugar

What 2 graded rows on akkermansia muciniphila agree on for blood sugar, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Akkermansia muciniphila page, with its PubMed record.

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Akkermansia muciniphila and blood sugar

2 rows · 134 people

Split. 1 row found an improvement and 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 2
Rows
2
Trials
2
People
134

Where they differ

From the rows
When published

The best-graded row, grade D, is a randomized trial of 76 people (2020) and found an improvement.

The row that found no difference is newer (2025) than the row that found an improvement (2020).

The rows

1 improved · 1 no difference
  1. Grade DPost-meal glucose in type 2 diabetes (multi-strain product with Akkermansia) · Improved

    RCT · n 76 · 2020 · Adults with type 2 diabetes

    Twice daily (counts not stated in the abstract) · 12 weeks

    Glucose area under the curve fell by 36.1 mg/dL/180 min versus placebo (P = 0.05), and HbA1c by 0.6 points; no safety or tolerability issues.

    Row on the Akkermansia muciniphila page · PubMed 32675291 (opens PubMed)

  2. Grade DWeight and HbA1c in type 2 diabetes with overweight · No difference

    RCT · n 58 · 2025 · Adults with type 2 diabetes and overweight or obesity

    Not stated in the abstract · 12 weeks

    Weight and HbA1c fell in both groups with no between-group difference; in people with low baseline Akkermansia, the strain colonized well and lowered weight, fat mass and HbA1c.

    Row on the Akkermansia muciniphila page · PubMed 39879980 (opens PubMed)

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