AHCC (Active Hexose Correlated Compound) and cancer care

What 3 graded rows on ahcc (active hexose correlated compound) agree on for cancer care, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the AHCC (Active Hexose Correlated Compound) page, with its PubMed record.

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AHCC (Active Hexose Correlated Compound) and cancer care

3 rows · 202 people

Split. 1 row found an improvement and 2 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 1
  • Grade D× 2
Rows
3
Trials
3
People
202

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 98 people (2023) and reported mixed results.

The rows run from 29 to 98 people, published from 2016 to 2023: 3 single studies.

The rows

1 improved · 2 mixed
  1. Grade DChemotherapy side effects in pancreatic cancer (non-randomised) · Improved

    Open-label trial · n 75 · 2016 · 75 patients with unresectable pancreatic cancer starting gemcitabine in Japan (35 AHCC, 40 no AHCC), not randomised

    6.0 g a day · 2 months

    Taste disorder was less frequent with AHCC (17% vs 56%, P = 0.0007); CRP rise and albumin fall were smaller, and grade 3 of the modified Glasgow Prognostic Score was less frequent (14% vs 53%).

    Row on the AHCC (Active Hexose Correlated Compound) page · PubMed 26847832 (opens PubMed)

  2. Grade CTaste disorders and anaemia during chemotherapy · Mixed

    RCT · n 98 · 2023 · 98 patients with pancreatic cancer on chemotherapy in Japan (55 AHCC, 43 placebo)

    Dose not stated in the abstract · During chemotherapy

    Taste disorders were less frequent with AHCC (risk difference 28.6%, 95% CI 7.5% to 47.8%) and nutrition markers improved; grade 2-3 anaemia did not differ (-3.1%).

    Row on the AHCC (Active Hexose Correlated Compound) page · PubMed 35950537 (opens PubMed)

  3. Grade DLiver cancer recurrence after surgery (single arm) · Mixed

    Open-label trial · n 29 · 2022 · 29 patients after curative surgery for hepatocellular carcinoma (BCLC stage A or B); 25 followed without stopping

    1 g three times a day (3 g a day) · 2 years

    2-year recurrence-free survival was 48% in those who did not stop and 55.2% in all treated; no toxicity or adverse events were seen. With no control group, the effect on recurrence cannot be judged.

    Row on the AHCC (Active Hexose Correlated Compound) page · PubMed 35075934 (opens PubMed)

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