Anti-AgingTarget: Pineal glandEndocrine

N-Acetyl Epitalon Amidate

NAEA · Ac-Epitalon-NH2 · acetylated amidated epitalon

NAEA is a stability-capped analog of Epitalon (N-acetyl, C-amide). It is not a Khavinson original, not Epithalamin, and not proof that parent telomerase papers transfer.

Not FDA-approved - research chemical

Quick answer

What it is: NAEA is a stability-capped analog of Epitalon (N-acetyl, C-amide).

Class and target: Stability analog (not a Khavinson original) · Pineal (parent AEDG) · sequence Ac-AEDG-NH2

Typical research dose: 5-10 mg/day (vendor longevity protocols; analog-specific PK absent)

Reconstitution calculator ↓

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team

·Last updated: August 2026·Evidence: Low

Typical research dose

5-10 mg/day (vendor longevity protocols; analog-specific PK absent)

Frequency

1× daily for 10-20 day cycles (vendor)

Half-life

Not published for this analog

Common vials

10 mg / 50 mg

CAS

N/A

Molecular weight

Tetrapeptide analog

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

Longevity / aging2/10
Caps on AEDG. Parent papers do not automatically transfer. No analog PK.

Compound card

Class: Acetyl/amide analog of AEDG (not parent Epitalon)
Formula: N-acetyl AEDG amide
Status: Not FDA-approved · research use

Dose it

10 mg + 2 mL BAC water → 5 mg/mL · 5000 mcg ≈ 100 units (U-100)

Open in calculator

How it works

NAEA is AEDG (epitalon) with an N-acetyl cap and C-terminal amide - the same exopeptidase-evasion trick as NASA on Semax. Parent epitalon/epithalamin literature is Khavinson pineal-tetrapeptide work (PMID 12937682). This analog does not have its own human PK paper.

Source: Parent epitalon PMID: 12937682. NAEA: no indexed human PK as of 2026.

Analog, not a second epitalon trial

Vendor 5 mg “longevity protocols” are not citations. If you need evidence, read epitalon and treat this as uncharacterized.

Khavinson map

Adjacent (not padded into the 41)

Class

Stability analog (not a Khavinson original)

Organ

Pineal (parent AEDG)

Target

Pineal gland

System

Endocrine

Sequence

Ac-AEDG-NH2

Pair

Parent Epitalon (AEDG)

The Khavinson school

N-Acetyl Epitalon Amidate is filed here as stability analog (not a khavinson original), targeting the pineal (parent aedg). Khavinson's St. Petersburg group moved from organ extracts (Cytamins) to capsule complexes (Cytomaxes) to synthetic short peptides (Cytogens); most of the evidence comes from that one group, with little independent Western replication.

Read the full background, the proposed epigenetic mechanism, the literature limits, and how we count the canonical 41 on the Khavinson bioregulators index.

History of this molecule

Same trick as NASA on Semax: block exopeptidases. Vendor longevity protocols exist. Analog-specific indexed human PK essentially does not. English “v3 bioregulator” talk is commercial taxonomy (Henry/PSI public marketing distinguishes product generations). We name the analog so buyers do not think they bought 2003 AEDG.

Caveats

Analog chemistry ≠ a second clinical program. Gray-market identity risk is higher, not lower, on “improved Epitalon.”

Full 41-map: Khavinson bioregulators index · Bioregulator stacks

Research Use Cases

✓Longevity analog SKU: Low

Dosing

Phase	Dose	Frequency	Notes
Vendor longevity SKU	5–10 mg/day	10–20 day courses	Inherited from epitalon practice. No analog trial.

Administration

Route / form

Stability analog of AEDG, sold as a lyophilized research vial. Not Endoluten capsules, not Epithalamin ampoules, not a Cytomed Epitalon blister, and not a sublingual tablet.

Timing

Research vial (SubQ): food does not change the injection. Not a Cytomed capsule course.

Empty stomach?

No - These are research vials, not Cytomed capsules. Food timing does not apply to SubQ.

N-Acetyl Epitalon Amidate: oral vs SubQ

Research NAEA vial

Bioavailability

Research SubQ of Ac-AEDG-NH2 (N-acetyl, C-amide). Analog chemistry to slow exopeptidases. Parent Epitalon PK is already thin; analog-specific indexed human PK is essentially absent as of 2026.

Dose note

Vendor folklore copies Epitalon 5–10 mg/day for 10–20 days. That is inheritance, not a head-to-head. Reconstitute like other lyophilized tetrapeptides only if the cake is this analog. Do not dose it as Epithalamin IM or as Endoluten capsules.

Advantages

Defined analog structure (when the COA matches Ac-AEDG-NH2).
Separable from parent AEDG, from pineal extract, and from pineal Cytomax.
SubQ is the real research presentation.

Considerations

Caps do not make PMID 12937682 an NAEA trial.
Gray-market “improved Epitalon” identity risk is higher, not lower.
Not a sublingual longevity melt.

Not Endoluten / not parent AEDG

Bioavailability

NAEA is not Endoluten and not a Cytomed Epitalon capsule. Oral pineal Cytomax is Endoluten. Oral AEDG cytogen is parent Epitalon. This analog is a research vial SKU.

Dose note

If you swallowed capsules, you did not take NAEA. No analog capsule course on this leaf.

Advantages

Keeps V3/marketing taxonomy from inventing an oral NAEA Cytomed box.
Sends capsule shoppers to Endoluten or parent Epitalon, correctly labeled.
Not a sublingual tablet. Nobody manufactures this SKU that way.

Considerations

Vendor “oral NAEA” listings are not a Khavinson paper.
Stability hope ≠ potency trial.
Not Epithalamin.

Recommendation: NAEA is a stability analog of Epitalon, sold as a research vial (SubQ). It is not in the 41. It is not Epitalon capsules, not Epithalamin IM extract, not Endoluten, and not a sublingual tablet. Do not copy parent 5–10 mg/day as if PK were identical.

Timeline

Unknown for analog

Do not copy telomere marketing onto NAEA.

Who it is for

Longevity analog SKU

Low

High catalog presence, near-zero analog papers.

Reconstitution

Vial	Water	Concentration	Example dose
10 mg lyophilized	2 mL BAC	5 mg/mL	Analog mg. Do not copy Epitalon 5–10 mg/day as if PK were identical.

Change vial size or water volume? Open the reconstitution calculator.

Safety & Considerations

Research analog. Parent claims (telomerase, pineal) are already contested. Analog does not make them stronger. Not a drug.

Regulatory & Legal Status

FDA Status (US)

Research Only

Stability analog of epitalon. No analog-specific human PK or approval

WADA Status (2026)

Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

No indexed human PK for the analog as of this review.

Verdict

NAEA is a stabilized Epitalon analog SKU. Parent AEDG telomerase papers are not a second clinical program. Epithalamin extract is still a different product.

Interactions & Contraindications

Research analog. Parent claims (telomerase, pineal) are already contested. Analog does not make them stronger. Not a drug.

N-Acetyl Epitalon Amidate vs. Epitalon

Canonical comparison: N-Acetyl Epitalon Amidate vs Epitalon

Attribute	N-Acetyl Epitalon Amidate	Epitalon
Structure	N-acetyl + C-amide AEDG	Parent AEDG tetrapeptide
Human PK	None for this analog	Thin even for the parent
SKU	NAEA / 5 mg vendor protocols	Standard epitalon vial

Verdict: Same cap trick as NASA. Parent papers stay on epitalon. Analog claims are chemistry inference.

Frequently Asked Questions

In the 41?▼

No. Stability analog of a core-eight molecule.

Stronger than Epitalon?▼

That is a medicinal-chemistry hope. It is not a head-to-head human trial.

Same as Epithalamin?▼

No. Extract vs analog of the synthetic.

V3?▼

Marketing language for later SKUs. Not a Khavinson paper classification.

Oral or injection?▼

Research vial / SubQ. Not Endoluten capsules, not Epithalamin IM, not a Cytomed Epitalon blister, not a sublingual tablet. Parent 5–10 mg/day does not automatically transfer.

Is this stronger than epitalon?▼

Unknown. Caps can slow breakdown. That is not a potency trial.

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