Xylitol and gut tolerance

What 2 graded rows on xylitol agree on for gut tolerance, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Xylitol page, with its PubMed record.

Your question

Xylitol and gut tolerance

2 rows · 184 people

Split. 1 row found no difference and 1 found a worse outcome.

No difference or worse
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Red: a worse outcome.
  • Grade C× 2
Rows
2
Trials
2
People
184

Where they differ

From the rows
Who was studied

The best-graded row, grade C, is a randomized trial of 120 people (2007) and found no difference.

Only the row that found no difference names children or teens in its population.

The rows

1 no difference · 1 worse
  1. Grade CGas and diarrhoea in toddlers on daily xylitol solution · No difference

    RCT · n 120 · 2007 · Children 6 to 36 months old in a practice-based research network (SCOR)

    5 g three times a day or 7.5 g once a day · 3 months

    Excessive gas or diarrhoea affected 10% to 27% of children on xylitol in a given month, which did not differ from placebo; withdrawals and visits for stomach complaints did not differ either. By month 3, about 90% accepted the solution easily or with minor difficulty.

    Row on the Xylitol page · PubMed 17097152 (opens PubMed)

  2. Grade CGut symptoms after one large dose in a drink · Worse

    RCT · n 64 · 2007 · Healthy students aged 18 to 24 at the University of Salford (UK)

    Single doses of 20, 35 and 50 g · One test day per dose, 7-day washouts

    50 g of xylitol increased nausea, bloating, rumbling, colic, watery stools and bowel movements compared with sucrose; 35 g also increased watery stools. At every dose xylitol caused more watery stools than erythritol.

    Row on the Xylitol page · PubMed 16988647 (opens PubMed)

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