Troxerutin and venous insufficiency
What 2 graded rows on troxerutin agree on for venous insufficiency, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Troxerutin page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Troxerutin page, with its PubMed record.
Your question
Troxerutin and venous insufficiency
2 rows · 1,703 peopleThey agree: both rows found an improvement.
- CGrade C× 1
- DGrade D× 1
- Rows
- 2
- Trials
- 2
- At least: a review without a trial count
- People
- 1,703
- Pooled reviews may count some twice
What the rows share
From the rowsThe best-graded row, grade C, is a meta-analysis of 1,643 people (2015) and found an improvement.
The rows run from 60 to 1,643 people, published from 2015 to 2017: 1 pooled review and 1 single study.
The rows
2 improved- CGrade CLeg pain, heaviness and cramps in chronic venous insufficiency · Improved
Meta-analysis · n 1,643 · 2015 · Adults with chronic venous insufficiency (15 RCTs)
As used in the pooled trials · As used in the pooled trials
Compared with placebo, hydroxyethylrutosides reduced leg pain (SMD -1.07), heavy legs (OR 0.50) and cramps (SMD -1.07). No serious adverse effects were reported.
- DGrade DSuperficial vein reflux during leg cast immobilization · Improved
RCT · n 60 · 2017 · Adults with a lower-limb fracture in a plaster cast (Turkey)
500 mg every 12 hours (1,000 mg/day) vs no treatment · 6 to 8 weeks of cast immobilization
Great saphenous vein dysfunction below the knee occurred in 13.3% with oxerutin versus 46.7% without, and small saphenous vein reflux in 10% versus 40%. No one developed venous thrombosis.