Thymus Extract and hepatitis

What 2 graded rows on thymus extract agree on for hepatitis, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Thymus Extract page, with its PubMed record.

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Thymus Extract and hepatitis

2 rows · 82 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 2
Rows
2
Trials
2
People
82

What the rows share

From the rows

The best-graded row, grade D, is a randomized trial of 50 people (1985) and reported mixed results.

The rows run from 32 to 50 people, published from 1985 to 1998: 2 single studies.

The rows

1 no difference · 1 mixed
  1. Grade DHepatitis C virus levels · No difference

    RCT · n 32 · 1998 · Adults with chronic hepatitis C who had not responded to or could not tolerate interferon (US tertiary centre)

    Label dose of the commercial product (not stated in the abstract) · 3 months vs placebo, then up to 6 months

    Viral RNA levels at 3 months did not differ from placebo (3.48 vs 4.06 million copies/mL, P>0.2). All 19 people who completed 6 months stayed virus-positive, with levels similar to baseline.

    Row on the Thymus Extract page · PubMed 9841585 (opens PubMed)

  2. Grade DLiver enzymes and HBsAg clearance in acute hepatitis B · Mixed

    RCT · n 50 · 1985 · Inpatients with acute hepatitis B

    1 ampoule twice daily vs placebo · 30 days

    AST, ALT and HBsAg clearance trended faster, but only the ALT decrease differed significantly from placebo.

    Row on the Thymus Extract page · PubMed 3916838 (opens PubMed)

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