Theacrine and exercise

What 4 graded rows on theacrine agree on for exercise, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Theacrine page, with its PubMed record.

Your question

Supplement
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Theacrine and exercise

4 rows · 78 people

Mostly no difference: 3 of 4 rows, and most of the people. 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 4
Rows
4
Trials
4
People
78

What the rows share

From the rows

The best-graded row, grade D, is a crossover trial of 24 people (2019) and reported mixed results.

The rows run from 12 to 24 people, published from 2019 to 2025: 4 single studies.

The rows

3 no difference · 1 mixed
  1. Grade DSprint, agility and running tests · No difference

    RCT · n 22 · 2022 · Amateur male flag-football athletes

    Single pre-workout dose (amount not stated in the abstract) · Single dose 60 minutes before testing

    No difference from placebo on jump, agility, 30 m sprint, 40-second run or 12-minute run tests.

    Row on the Theacrine page · PubMed 36360914 (opens PubMed)

  2. Grade DSprint kayak performance · No difference

    Crossover RCT · n 20 · 2025 · Highly trained male canoe sprint athletes

    Not stated in the abstract · Single dose per condition

    Theacrine alone did not improve 500 m time or Wingate distance; caffeine did (500 m about 1.9 seconds faster), and the combination gave smaller significant gains. Heart rate and blood pressure did not differ.

    Row on the Theacrine page · PubMed 41320283 (opens PubMed)

  3. Grade DStrength, power and rowing performance · No difference

    Crossover RCT · n 12 · 2019 · Resistance-trained men

    300 mg TeaCrine, or 150 mg TeaCrine with 150 mg caffeine · Single dose 90 minutes before exercise

    No condition improved 1-rep max, reps to failure, power or 2 km rowing; only 300 mg caffeine raised energy, focus and motivation compared with TeaCrine.

    Row on the Theacrine page · PubMed 31660991 (opens PubMed)

  4. Grade DEndurance and reaction time in a simulated soccer match · Mixed

    Crossover RCT · n 24 · 2019 · High-level male and female soccer players

    Not stated in the abstract · Four sessions, one per condition

    Time to exhaustion trended higher with TeaCrine and with TeaCrine plus caffeine (P<0.052, not significant); choice reaction time was faster with caffeine and with the combination, not with TeaCrine alone.

    Row on the Theacrine page · PubMed 30999897 (opens PubMed)

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