Sodium bicarbonate (baking soda) and exercise

What 4 graded rows on sodium bicarbonate (baking soda) agree on for exercise, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Sodium bicarbonate (baking soda) page, with its PubMed record.

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Sodium bicarbonate (baking soda) and exercise

4 rows · 2,587 people

Mostly an improvement: 3 of 4 rows, and most of the people. 1 had mixed results.

Mixed
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade B× 2
  • Grade C× 2
Rows
4
Trials
238
People
2,587
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade B, is a meta-analysis of 2,019 people (2022) and found an improvement.

The rows run from 126 to 2,019 people, published from 2022 to 2026: 4 pooled reviews and 0 single studies.

The rows

3 improved · 1 mixed
  1. Grade BHigh-intensity exercise capacity and performance · Improved

    Meta-analysis, 189 studies · n 2,019 · 2022 · Adults in 189 placebo-controlled studies (158 with sodium bicarbonate)

    Varied; typically 0.2–0.3 g/kg · Single dose to multi-day

    Overall effect versus placebo ES 0.17 (95% CrI 0.12–0.21); largest for 0.5–10 minute efforts (ES 0.18) and >10 minutes (ES 0.22). Blood bicarbonate rose 5.2 mmol/L.

    Row on the Sodium bicarbonate (baking soda) page · PubMed 34687438 (opens PubMed)

  2. Grade BCycling time-trial performance · Improved

    Meta-analysis, 18 studies · n 201 · 2023 · Cyclists in 18 placebo-controlled trials

    Varied by trial; standardized timing or individual time-to-peak · Single dose

    Versus placebo, mean power rose (SMD 0.42, 95% CI 0.21–0.63) and time-trial performance time improved (SMD 0.22, 95% CI 0.02–0.43), with no heterogeneity (I² = 0%).

    Row on the Sodium bicarbonate (baking soda) page · PubMed 35633035 (opens PubMed)

  3. Grade CHigh-intensity intermittent exercise in team sports · Improved

    Meta-analysis, 20 studies · n 241 · 2026 · Team-sport athletes in 20 randomized trials

    Varied by trial · Single dose to short-term

    Small benefit for intermittent high-intensity performance (Hedges' g 0.23, 95% CI 0.07–0.39), but no clear effect on repeated sprints, mean power or intermittent endurance; the prediction interval crossed zero.

    Row on the Sodium bicarbonate (baking soda) page · PubMed 42781544 (opens PubMed)

  4. Grade CContinuous running performance · Mixed

    Meta-analysis, 11 studies · n 126 · 2025 · Mostly male runners in 11 crossover trials

    Typically 0.3 g/kg · Single dose

    After adjusting for GI-related withdrawals and publication bias, the effect was negligible and not significant (SMD 0.18, 95% CI −0.01 to 0.36); GI symptoms 29.5% vs 2.6% with placebo.

    Row on the Sodium bicarbonate (baking soda) page · PubMed 41416636 (opens PubMed)

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