Shiitake and immune markers
What 2 graded rows on shiitake agree on for immune markers, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Shiitake page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Shiitake page, with its PubMed record.
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Shiitake and immune markers
2 rows · 94 peopleSplit. 1 row found an improvement and 1 had mixed results.
- CGrade C× 1
- DGrade D× 1
- Rows
- 2
- Trials
- 2
- People
- 94
What the rows share
From the rowsThe best-graded row, grade C, is a crossover trial of 42 people (2011) and reported mixed results.
The rows run from 42 to 52 people, published from 2011 to 2015: 2 single studies.
The rows
1 improved · 1 mixed- DGrade DImmune-cell activity in healthy adults · Improved
Open-label trial · n 52 · 2015 · Healthy men and women aged 21 to 41
5 or 10 g/day · 4 weeks
Ex vivo proliferation of gamma-delta T cells rose 60% and of NK-T cells 2-fold (p < 0.0001); salivary sIgA rose and CRP fell.
- CGrade CImmune markers in healthy older adults · Mixed
Crossover RCT · n 42 · 2011 · 42 healthy elderly people
2.5 mg/day · 6 weeks per arm, 4-week washout
Changes in B-cell numbers differed from placebo; NK cells rose in both groups; immunoglobulins, complement and cytokines did not change. Adverse events were similar to placebo.