Shiitake and blood fats
What 2 graded rows on shiitake agree on for blood fats, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Shiitake page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Shiitake page, with its PubMed record.
Your question
Shiitake and blood fats
2 rows · 120 peopleSplit. 1 row found an improvement and 1 found no difference.
- CGrade C× 1
- ∅No effect× 1
- Rows
- 2
- Trials
- 2
- People
- 120
Where they differ
From the rowsThe best-graded row, grade C, is a randomized trial of 68 people (2021) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.
The row that found an improvement ran longer (2 months) than the row that found no difference (8 weeks).
The rows
1 improved · 1 no difference- CGrade CTriglycerides and antioxidant markers in borderline high cholesterol · Improved
RCT · n 68 · 2021 · Individuals with borderline high cholesterol, LDL or triglycerides (36 shiitake, 32 placebo)
Not stated in the abstract · 66 days
Triglycerides fell 10% after 66 days in the shiitake group (p = 0.0352); glutathione rose and lipid peroxidation fell. Dermatitis was triggered in 10% of individuals sensitive to the mushroom.
- ∅No effectCholesterol in mild hypercholesterolaemia · No difference
RCT · n 52 · 2021 · Adults aged 18 to 65 with untreated mild hypercholesterolaemia
10.4 g/day (3.5 g fungal beta-glucans) · 8 weeks
No differences vs placebo in lipid or cholesterol measures, and no change in IL-1β, IL-6, TNF-α or oxidised LDL; gut bacteria shifted differently from placebo.