Rutin and blood sugar

What 3 graded rows on rutin agree on for blood sugar, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Rutin page, with its PubMed record.

Your question

Rutin and blood sugar

3 rows · 181 people

Mostly no difference: 2 of 3 rows, and most of the people. 1 found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 3
Rows
3
Trials
3
People
181

Where they differ

From the rows
How long

The best-graded row, grade D, is a randomized trial of 78 people (2023) and found no difference.

The row that found an improvement ran longer (3 months) than the 2 rows that found no difference (8 weeks to 3 months).

The rows

1 improved · 2 no difference
  1. Grade DInsulin-producing (beta-cell) function and gut bacteria in overweight adults without diabetes · No difference

    RCT · n 78 · 2023 · Adults aged 18–65 with overweight and normal glucose or prediabetes (New Zealand)

    500 mg/day · 12 weeks

    Neither rutin capsules nor rutin yoghurt changed beta-cell response to an oral glucose tolerance test or gut bacterial composition versus placebo.

    Row on the Rutin page · PubMed 37571297 (opens PubMed)

  2. Grade DGlycemic control with rutin plus vitamin C in type 2 diabetes · No difference

    RCT · n 53 · 2020 · Adults with type 2 diabetes (registered trial NCT03437902)

    Not stated in the abstract · 8 weeks

    The percentage fall in fasting glucose was larger with vitamin C, with or without rutin, than with usual treatment alone; HbA1c, insulin, HOMA-IR, total cholesterol and oxidative-stress markers did not change. The abstract reports no advantage of the rutin combination over vitamin C alone.

    Row on the Rutin page · PubMed 31987106 (opens PubMed)

  3. Grade DBlood sugar, insulin resistance and lipids in type 2 diabetes · Improved

    RCT · n 50 · 2023 · Adults with type 2 diabetes

    500 mg/day · 3 months

    In the adjusted analysis, fasting glucose, insulin, HbA1c, HOMA-IR, LDL and total cholesterol, IL-6 and malondialdehyde fell more, and HDL, QUICKI and total antioxidant capacity rose more, than with placebo.

    Row on the Rutin page · PubMed 36101997 (opens PubMed)

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