Punicalagins (Pomegranate Ellagitannins) and blood sugar

What 2 graded rows on punicalagins (pomegranate ellagitannins) agree on for blood sugar, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Punicalagins (Pomegranate Ellagitannins) page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Punicalagins (Pomegranate Ellagitannins) page, with its PubMed record.

Supplement

Punicalagins (Pomegranate Ellagitannins) Choose another

2 rows · 689 people

They agree: both rows found no difference.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade C, is a meta-analysis of 673 people (2025) and found no difference.

The rows run from 16 to 673 people, published from 2017 to 2025: 1 pooled review and 1 single study.

2 no difference

Grade CInsulin resistance (HOMA-IR) and insulin sensitivity · No difference
Meta-analysis, 15 studies · n 673 · 2025 · Participants in 15 RCTs (healthy, overweight, NAFLD, type 2 diabetes, PCOS and others)
Varied · At least 4 weeks
Pomegranate products did not improve HOMA-IR or insulin sensitivity overall; subgroups with PCOS (HOMA-IR and fasting insulin) and with type 2 diabetes or NAFLD (fasting insulin) improved.
Row on the Punicalagins (Pomegranate Ellagitannins) page · PubMed 39499092 (opens PubMed)
Grade DPost-meal blood sugar after bread · No difference
Crossover RCT · n 16 · 2017 · Healthy volunteers
Not stated in the abstract · Single meal
The extract did not lower the blood glucose response to bread, whereas pomegranate juice lowered it by 33.1% in a parallel study of 16 people.
Row on the Punicalagins (Pomegranate Ellagitannins) page · PubMed 29021286 (opens PubMed)