Psyllium and metabolic

What 2 graded rows on psyllium agree on for metabolic, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Psyllium page, with its PubMed record.

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Psyllium and metabolic

2 rows · 1,316 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade B× 1
  • Grade C× 1
Rows
2
Trials
2
At least: a review without a trial count
People
1,316
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade B, is a meta-analysis of 962 people (2024) and found an improvement.

The rows run from 354 to 962 people, published from 2023 to 2024: 2 pooled reviews and 0 single studies.

The rows

1 improved · 1 mixed
  1. Grade BFasting blood sugar, HbA1c and insulin resistance · Improved

    Meta-analysis · n 962 · 2024 · Adults in 19 RCTs

    Varied; subgroups below and above 10 g/day · Varied; fasting blood sugar not significant in trials shorter than 50 days

    Fasting blood sugar fell by 6.89 mg/dL, HbA1c by 0.75 and HOMA-IR by 1.17 versus placebo; insulin did not change significantly. HbA1c was not significantly lower with less than 10 g/day.

    Row on the Psyllium page · PubMed 38844885 (opens PubMed)

  2. Grade CBody weight, BMI and waist size · Mixed

    Meta-analysis · n 354 · 2023 · Participants with overweight or obesity in 6 RCTs of at least 2 months

    Mean 10.8 g/day · Mean 4.8 months

    Body weight fell by 2.1 kg, BMI by 0.8 and waist by 2.2 cm. A 2020 meta-analysis of 22 RCTs found no significant change in weight, BMI or waist, and a 2025 analysis of 27 RCTs reported weight 3.57 kg higher with psyllium, so the overall picture is conflicting.

    Row on the Psyllium page · PubMed 37163454 (opens PubMed)

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