Oral ATP (Adenosine Triphosphate) and strength

What 5 graded rows on oral atp (adenosine triphosphate) agree on for strength, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Oral ATP (Adenosine Triphosphate) page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Oral ATP (Adenosine Triphosphate) page, with its PubMed record.

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Strength5 Absorption2

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Oral ATP (Adenosine Triphosphate) and strength

5 rows · 191 people

Split. 2 rows found an improvement, 1 found no difference and 2 had mixed results.

No difference or mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

Grade C× 1
Grade D× 3
No effect× 1

Rows: 5
Trials: 9
People: 191; Pooled reviews may count some twice

Where they differ

From the rows

When published

The best-graded row, grade C, is a meta-analysis of 121 people (2024) and reported mixed results. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The row that found no difference is newer (2024) than the 2 rows that found an improvement (2013 to 2019).

2 rows with mixed results are left out of this comparison.

The rows

2 improved · 1 no difference · 2 mixed

Grade DStrength, power and muscle thickness in trained men · Improved
RCT · n 21 · 2013 · 21 resistance-trained men completed (11 ATP, 10 placebo; full text)
400 mg a day · 12 weeks
Total body strength rose 55.3 kg with ATP vs 22.4 kg with placebo (p<0.001); vertical jump power 796 vs 614 watts; muscle thickness 4.9 vs 2.5 mm (p<0.02).
Row on the Oral ATP (Adenosine Triphosphate) page · PubMed 24330670 (opens PubMed)
Grade DSquat volume after one dose · Improved
Crossover RCT · n 11 · 2019 · Eleven recreationally trained men
400 mg once, 30 minutes before · Single session
Total weight lifted was higher with ATP (4,967.4 kg) than placebo (3,995.7 kg; p = 0.005); heart rate and oxygen use were higher.
Row on the Oral ATP (Adenosine Triphosphate) page · PubMed 29045315 (opens PubMed)
No effectIsokinetic knee strength after one dose · No difference
Crossover RCT · n 18 · 2024 · 18 trained men
400 mg once, 30 minutes before · Single session
No significant improvement in muscle strength; the drop in knee-extension strength across sets was delayed vs placebo.
Row on the Oral ATP (Adenosine Triphosphate) page · PubMed 38193939 (opens PubMed)
Grade CMaximal strength, repetitions and anaerobic power · Mixed
Meta-analysis, 5 studies · n 121 · 2024 · 121 resistance-trained men in five RCTs
Mostly 400 mg, acute or daily · Acute (30 min to 24 h before tests) or daily (more than 1 day)
Maximal strength gains were greater than placebo (MD = 8.13 kg, 95%CI 3.36-12.90); maximum repetitions and anaerobic power did not differ.
Row on the Oral ATP (Adenosine Triphosphate) page · PubMed 38535745 (opens PubMed)
Grade DSquat repetitions at 100, 200 or 400 mg · Mixed
Crossover RCT · n 20 · 2021 · Twenty recreationally trained men
100, 200 or 400 mg once · Single sessions a week apart
400 mg raised set-1 repetitions by 13% (p = 0.04), but total repetitions (+7%, p = 0.19) and weight lifted (+6%, p = 0.22) did not differ significantly; 100 mg had no benefit.
Row on the Oral ATP (Adenosine Triphosphate) page · PubMed 34957398 (opens PubMed)

Read onRead the full evidenceThe full evidence chapter on its page, with every outcome and its sources.