Methylcellulose and gas

What 2 graded rows on methylcellulose agree on for gas, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Methylcellulose page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Methylcellulose page, with its PubMed record.

Supplement

Methylcellulose Choose another

2 rows · 52 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade D, is a crossover trial of 30 people (2026) and found no difference.

The rows run from 22 to 30 people, published in 2026: 2 single studies.

1 no difference · 1 mixed

Grade DEarly breath hydrogen after inulin (non-inferiority to psyllium) · No difference
Crossover RCT · n 30 · 2026 · Healthy volunteers (UK)
Single dose co-administered with inulin (vs psyllium or maltodextrin) · Single dose, 24 hours of breath testing
Psyllium reduced early breath hydrogen versus placebo, but methylcellulose was not shown to be non-inferior to psyllium.
Row on the Methylcellulose page · PubMed 41636227 (opens PubMed)
Grade DColonic gas after a fermentable fiber (inulin) · Mixed
Crossover RCT · n 22 · 2026 · Healthy volunteers (UK)
15 g methylcellulose with 15 g inulin, single dose (vs psyllium or maltodextrin) · Single dose, 24 hours of MRI and breath testing
Methylcellulose and psyllium did not change total colonic gas over 6 hours, but both were linked to less colonic gas once the gels reached the colon (3 to 6 hours). 24-hour breath hydrogen did not differ between groups.
Row on the Methylcellulose page · PubMed 42728685 (opens PubMed)