Luteolin and smell recovery
What 4 graded rows on luteolin agree on for smell recovery, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Luteolin page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Luteolin page, with its PubMed record.
Your question
Luteolin and smell recovery
4 rows · 962 peopleSplit. 2 rows found an improvement, 1 found no difference and 1 had mixed results.
- BGrade B× 1
- CGrade C× 2
- DGrade D× 1
- Rows
- 4
- Trials
- 10
- People
- 962
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade B, is a meta-analysis of 525 people (2026) and found an improvement.
The 2 rows that found an improvement were larger: a median of 355 people, against 50 people for the row that found no difference.
Only the 2 rows that found an improvement include pooled reviews of several trials (1 of 2); the row that found no difference is a single study.
The best grade is B among the rows that found an improvement, and D among the row that found no difference.
1 row with mixed results is left out of this comparison.
The rows
2 improved · 1 no difference · 1 mixed- BGrade BSmell recovery after COVID-19 (PEA-LUT plus smell training vs training alone) · Improved
Meta-analysis, 7 studies · n 525 · 2026 · Adults with smell loss after COVID-19 in 7 RCTs published 2021–2024
Varied by trial · Varied by trial
Smell test scores were higher with PEA-LUT plus training than training alone (SMD 0.90, 95% CI 0.24 to 1.58), and more people responded (risk difference 0.33, 95% CI 0.01 to 0.64).
- CGrade CSmell recovery after COVID-19 (PEA-LUT plus smell training) · Improved
RCT · n 185 · 2022 · Adults with smell loss lasting more than 6 months after COVID-19 (multicenter)
770 mg/day PEA-LUT · 90 days
Smell threshold, discrimination and identification improved more than with smell training plus placebo; 92% vs 42% improved.
- DGrade DClinically meaningful smell recovery (PEA-LUT plus training vs training alone, 2024) · No difference
RCT · n 50 · 2024 · Adults with post-infectious smell loss, mainly after COVID-19 (outpatient clinic)
Not stated in the abstract · Not stated in the abstract
The PEA-LUT group improved on odor discrimination and total smell score, but clinically meaningful improvement did not differ from smell training alone.
- CGrade CSmell identification after COVID-19 (PEA-LUT alone or with training) · Mixed
RCT · n 202 · 2023 · Adults with smell loss lasting more than 6 months after COVID-19 (multicenter)
Once or twice daily (amount not stated in the abstract) · 90 days
With smell training, 89.2% improved by more than 3 points vs 36.8% with training plus placebo; PEA-LUT alone (40–41.6%) was close to placebo for that endpoint. No adverse events.