Lithothamnion (Aquamin) and gut

What 3 graded rows on lithothamnion (aquamin) agree on for gut, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Lithothamnion (Aquamin) page, with its PubMed record.

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Lithothamnion (Aquamin) and gut

3 rows · 74 people

Mostly an improvement: 2 of 3 rows, and most of the people. 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 3
Rows
3
Trials
3
People
74

What the rows share

From the rows

The best-graded row, grade D, is a randomized trial of 30 people (2020) and reported mixed results.

The rows run from 16 to 30 people, published from 2020 to 2026: 3 single studies.

The rows

2 improved · 1 mixed
  1. Grade DInflammation and bone markers in ulcerative colitis in remission or mild · Improved

    RCT · n 28 · 2025 · Adults with ulcerative colitis in remission or with mild disease

    Daily capsules (amount not stated in the abstract) · 180 days (placebo arm switched to Aquamin at day 90)

    Combined inflammation-marker differences fell 24% with Aquamin vs a 38% rise on placebo (p = 0.0284); hip strength index rose 7.3% after 180 days.

    Row on the Lithothamnion (Aquamin) page · PubMed 41359652 (opens PubMed)

  2. Grade DGut permeability in ulcerative colitis · Improved

    Open-label trial · n 16 · 2026 · People with mild or inactive ulcerative colitis and healthy controls (8 per group)

    800 mg calcium a day · 90 days

    In ulcerative colitis, total urinary mannitol excretion (a permeability marker) fell 29% after 90 days (p = 0.024); no serious adverse events.

    Row on the Lithothamnion (Aquamin) page · PubMed 42440705 (opens PubMed)

  3. Grade DColon bacteria and stool metabolites · Mixed

    RCT · n 30 · 2020 · Healthy adults (Aquamin, calcium alone or placebo)

    Amount delivering 800 mg calcium a day · 90 days

    Total bacterial DNA in colon biopsies fell (P = 0.0001) and stool bile acids fell (P = 0.0375) with Aquamin; acetate rose slightly. Liver and kidney markers did not change.

    Row on the Lithothamnion (Aquamin) page · PubMed 31771942 (opens PubMed)

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