Licorice root (Glycyrrhiza glabra) and digestion

What 2 graded rows on licorice root (glycyrrhiza glabra) agree on for digestion, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Licorice root (Glycyrrhiza glabra) page, with its PubMed record.

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Licorice root (Glycyrrhiza glabra) and digestion

2 rows · 250 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade B× 1
  • Grade D× 1
Rows
2
Trials
2
People
250

What the rows share

From the rows

The best-graded row, grade B, is a randomized trial of 200 people (2025) and found an improvement.

The rows run from 50 to 200 people, published from 2012 to 2025: 2 single studies.

The rows

2 improved
  1. Grade BReflux symptoms and reflux-related quality of life · Improved

    RCT · n 200 · 2025 · Adults with gastro-oesophageal reflux symptoms (India)

    75 mg twice daily (150 mg/day) · 28 days

    Reflux quality-of-life scores were better than placebo at day 28 (p = 0.014), and heartburn and regurgitation resolved sooner, within about 2 weeks.

    Row on the Licorice root (Glycyrrhiza glabra) page · PubMed 39929150 (opens PubMed)

  2. Grade DFunctional dyspepsia symptoms · Improved

    RCT · n 50 · 2012 · Adults with functional dyspepsia (Rome III; India)

    75 mg twice daily · 30 days

    Total symptom scores and Nepean Dyspepsia Index improved more than placebo at days 15 and 30 (P ≤ 0.05); well tolerated.

    Row on the Licorice root (Glycyrrhiza glabra) page · PubMed 21747893 (opens PubMed)

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