Lactobacillus fermentum and infant infections
What 2 graded rows on lactobacillus fermentum agree on for infant infections, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Lactobacillus fermentum page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Lactobacillus fermentum page, with its PubMed record.
Your question
Lactobacillus fermentum and infant infections
2 rows · 895 peopleSplit. 1 row found an improvement and 1 found no difference.
- CGrade C× 1
- ∅No effect× 1
- Rows
- 2
- Trials
- 2
- People
- 895
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade C, is a meta-analysis of 435 people (2021) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.
The row that found an improvement is a pooled review of several trials; the row that found no difference is a single study.
The row that found no difference is newer (2024) than the row that found an improvement (2021).
The rows
1 improved · 1 no difference- CGrade CGut infections in formula-fed infants · Improved
Meta-analysis · n 435 · 2021 · Infants up to 12 months in 3 RCTs
About 0.84-1 billion CFU a day · Up to 12 months
Gut infection incidence was about halved (IRR 0.52, 95% CI 0.36-0.74); heterogeneity was moderate (I2 54.5%).
Row on the Lactobacillus fermentum page · PubMed 34208893 (opens PubMed)
- ∅No effectInfectious diarrhoea in formula-fed infants · No difference
RCT · n 460 · 2024 · Healthy 1-month-old formula-fed infants in France, followed to 12 months
In formula (amount not stated in the abstract) · Until 12 months of age
Infectious diarrhoea rates in the first year did not differ (0.56 vs 0.60 episodes per infant-year). Lower respiratory tract infections, a secondary outcome, were less frequent (0.79 vs 1.01; rate ratio 0.77, 95% CI 0.60-1.00).
Row on the Lactobacillus fermentum page · PubMed 38462218 (opens PubMed)