Hesperidin and blood vessels
What 2 graded rows on hesperidin agree on for blood vessels, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Hesperidin page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Hesperidin page, with its PubMed record.
Your question
Hesperidin and blood vessels
2 rows · 105 peopleThey agree: both rows found no difference.
- DGrade D× 2
- Rows
- 2
- Trials
- 2
- People
- 105
What the rows share
From the rowsThe best-graded row, grade D, is a randomized trial of 68 people (2016) and found no difference.
The rows run from 37 to 68 people, published from 2016 to 2026: 2 single studies.
The rows
2 no difference- DGrade DBlood vessel function (flow-mediated dilation) · No difference
RCT · n 68 · 2016 · Healthy adults with overweight or obesity
450 mg/day · 6 weeks
Fasting and after-meal flow-mediated dilation did not change versus placebo; blood pressure and adhesion molecules showed only non-significant trends in the full group.
- DGrade DBlood vessel function (flow-mediated dilation) · No difference
Crossover RCT · n 37 · 2026 · Men with central overweight
210 mg hesperidin/day, or 330 mL orange juice · 6 weeks per period
Neither orange juice nor hesperidin changed fasting or after-meal flow-mediated dilation, or other vascular, metabolic or body measures, versus control, despite similar hesperetin exposure.