Grape seed extract and blood sugar

What 2 graded rows on grape seed extract agree on for blood sugar, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Grape seed extract page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Grape seed extract page, with its PubMed record.

Supplement

Grape seed extract Choose another

2 rows · 74 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade D, is a randomized trial of 42 people (2021) and found an improvement.

The rows run from 32 to 42 people, published from 2009 to 2021: 2 single studies.

1 improved · 1 mixed

Grade DInsulin resistance in adolescents with metabolic syndrome · Improved
RCT · n 42 · 2021 · Iranian adolescents with metabolic syndrome on a weight-loss diet (48 randomised, 42 completed)
100 mg/day · 8 weeks
HOMA-IR fell 1.46 on extract vs 0.48 on placebo (p = 0.020) and insulin 7.05 vs 1.71 (p = 0.024); other measures, including blood pressure, did not differ significantly.
Row on the Grape seed extract page · PubMed 33385766 (opens PubMed)
Grade DBlood-sugar and inflammation markers in type 2 diabetes · Mixed
Crossover RCT · n 32 · 2009 · Obese adults with type 2 diabetes at high cardiovascular risk
600 mg/day · 4 weeks per period
Fructosamine and hsCRP fell and glutathione rose after grape seed extract but not placebo; endothelial function and insulin resistance did not change.
Row on the Grape seed extract page · PubMed 19646193 (opens PubMed)