Fucoidan and blood sugar

What 3 graded rows on fucoidan agree on for blood sugar, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Fucoidan page, with its PubMed record.

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Fucoidan and blood sugar

3 rows · 167 people

Split. 1 row found an improvement, 1 found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 1
  • Grade D× 1
  • No effect× 1
Rows
3
Trials
3
People
167

Where they differ

From the rows
When published

The best-graded row, grade C, is a randomized trial of 70 people (2025) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The row that found an improvement is newer (2025) than the row that found no difference (2019).

1 row with mixed results is left out of this comparison.

The rows

1 improved · 1 no difference · 1 mixed
  1. Grade CBlood sugar and inflammation in prediabetes · Improved

    RCT · n 70 · 2025 · 70 Chinese adults with prediabetes

    1000 mg a day · 12 weeks

    Glycated serum protein rose less and TNF-α, IL-6 and LPS fell compared with placebo (P < 0.05); Megamonas and Blautia rose and Klebsiella fell in the gut.

    Row on the Fucoidan page · PubMed 39645105 (opens PubMed)

  2. No effectInsulin resistance in obese adults · No difference

    RCT · n 72 · 2019 · Obese adults without diabetes in Tasmania (35 fucoidan, 37 placebo)

    500 mg twice daily · 90 days

    No differences in any 90-day outcome; mean HOMA change was 0 on placebo and -0.1 on fucoidan (p = 0.73).

    Row on the Fucoidan page · PubMed 30312135 (opens PubMed)

  3. Grade DInsulin secretion, blood pressure and LDL in overweight adults · Mixed

    RCT · n 25 · 2014 · 25 overweight or obese volunteers in Mexico (13 fucoidan, 12 placebo)

    500 mg once daily before breakfast · 3 months

    Diastolic blood pressure (71.7 to 67.8 mmHg) and LDL cholesterol (3.1 to 2.7 mmol/l) fell, while insulin, HOMA beta-cell and HOMA-IR (1.9 to 2.6) rose after fucoidan.

    Row on the Fucoidan page · PubMed 24611906 (opens PubMed)

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