Eucommia bark (Du Zhong) and blood pressure

What 4 graded rows on eucommia bark (du zhong) agree on for blood pressure, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Eucommia bark (Du Zhong) page, with its PubMed record.

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Eucommia bark (Du Zhong) and blood pressure

4 rows · 248 people

Split. 2 rows found an improvement and 2 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
  • Grade D× 2
Rows
4
Trials
4
People
248

Where they differ

From the rows
How long

The best-graded row, grade C, is a randomized trial of 136 people (2025) and found no difference.

The 2 rows that found no difference ran longer (8 weeks to 3 months) than the 2 rows that found an improvement (2 to 4 weeks).

The rows

2 improved · 2 no difference
  1. Grade COffice and 24-hour blood pressure in grade 1 hypertension · Improved

    RCT · n 58 · 2022 · Chinese adults with low-to-moderate-risk grade 1 hypertension (3 centres)

    Not stated in the abstract · 4 weeks (after a 1-week sham lead-in)

    Office systolic and diastolic pressure changed by -7.62 and -4.66 mmHg (p < .05) and diastolic variability improved versus control; no differences in other measures, including most 24-hour readings. Adverse events were mild.

    Row on the Eucommia bark (Du Zhong) page · PubMed 36703729 (opens PubMed)

  2. Grade DBlood pressure in mildly raised blood pressure (2 weeks) · Improved

    RCT · n 30 · 2011 · Healthy US adults with blood pressure 120-160/80-100 mmHg

    1 g three times daily (3 g/day) · 2 weeks

    24-hour ambulatory blood pressure fell by an average of 7.5/3.9 mmHg and the extract was well tolerated.

    Row on the Eucommia bark (Du Zhong) page · PubMed 22214253 (opens PubMed)

  3. Grade CBlood-pressure rhythm when added to usual medicines · No difference

    RCT · n 136 · 2025 · Chinese adults with essential hypertension and an abnormal day-night blood-pressure rhythm, on their usual medicines

    1.48 g twice daily · 12 weeks

    No significant difference in blood-pressure variability (SD and CV) in the full or per-protocol analysis. In the subgroup not using calcium channel blockers, 24-hour diastolic variability improved more.

    Row on the Eucommia bark (Du Zhong) page · PubMed 41132538 (opens PubMed)

  4. Grade DBlood pressure in mildly raised blood pressure (8 weeks, lower dose) · No difference

    RCT · n 24 · 2011 · Healthy US adults with blood pressure 120-160/80-100 mmHg

    500 mg three times daily (1.5 g/day) · 8 weeks

    No difference in 24-hour ambulatory blood pressure between the two groups and no toxicity.

    Row on the Eucommia bark (Du Zhong) page · PubMed 22214253 (opens PubMed)

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