Essential Amino Acids (EAAs) and sarcopenia

What 2 graded rows on essential amino acids (eaas) agree on for sarcopenia, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Essential Amino Acids (EAAs) page, with its PubMed record.

Your question

Supplement
Essential Amino Acids (EAAs) Choose another

Essential Amino Acids (EAAs) and sarcopenia

2 rows · 651 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
Rows
2
Trials
10
People
651
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 496 people (2026) and found an improvement.

The rows run from 155 to 496 people, published from 2012 to 2026: 1 pooled review and 1 single study.

The rows

1 improved · 1 mixed
  1. Grade CStrength and physical function with resistance training in sarcopenia · Improved

    Meta-analysis, 9 studies · n 496 · 2026 · Older adults with sarcopenia (9 RCTs)

    Varied across trials · Varied across trials

    Compared with resistance training alone, adding amino acids improved grip strength (SMD 0.69), gait speed (SMD 0.64), Short Physical Performance Battery scores (SMD 1.69) and sit-to-stand time; skeletal muscle mass did not change. Certainty was low to very low.

    Row on the Essential Amino Acids (EAAs) page · PubMed 41540398 (opens PubMed)

  2. Grade CLeg muscle mass, strength and walking speed in sarcopenic women · Mixed

    RCT · n 155 · 2012 · Community-dwelling sarcopenic women aged 75+ (Tokyo)

    3 g twice daily (6 g/day) · 3 months

    Walking speed rose in all intervention groups, but leg muscle mass rose only in the exercise groups and knee strength only with exercise plus EAAs (9.3%); EAAs alone did not raise muscle mass.

    Row on the Essential Amino Acids (EAAs) page · PubMed 22142410 (opens PubMed)

Educational only. Not medical advice. Some links earn us a commission: kymatahealth.com/affiliate-disclosure.