Butterbur and hay fever
What 3 graded rows on butterbur agree on for hay fever, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Butterbur page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Butterbur page, with its PubMed record.
Your question
Butterbur and hay fever
3 rows · 551 peopleMostly an improvement: 2 of 3 rows, and most of the people. 1 found no difference.
- CGrade C× 3
- Rows
- 3
- Trials
- 3
- People
- 551
Where they differ
From the rowsThe best-graded row, grade C, is a randomized trial of 330 people (2005) and found an improvement.
The 2 rows that found an improvement were larger: a median of 258 people, against 35 people for the row that found no difference.
The rows
2 improved · 1 no difference- CGrade CIntermittent allergic rhinitis symptoms versus placebo and fexofenadine · Improved
RCT · n 330 · 2005 · Adults with intermittent allergic rhinitis
1 tablet three times daily · 2 weeks
Butterbur and fexofenadine were each better than placebo (p<0.001) and did not differ from each other.
- CGrade CIntermittent allergic rhinitis symptoms · Improved
RCT · n 186 · 2004 · Adults with skin-test-confirmed intermittent allergic rhinitis
1 tablet twice or three times daily · 2 weeks
Daytime symptoms improved more than placebo with a dose-response between the two doses; adverse events were similar to placebo.
- CGrade CNasal airflow and symptoms during grass pollen season · No difference
Crossover RCT · n 35 · 2004 · Adults with intermittent allergic rhinitis (Scotland)
50 mg twice daily · 2 weeks per arm
No significant effect on peak nasal inspiratory flow, nasal or eye symptoms, or quality of life versus placebo.