Bromelain and joints

What 2 graded rows on bromelain agree on for joints, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Bromelain page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Bromelain page, with its PubMed record.

Supplement

Bromelain Choose another

2 rows · 87 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade D, is a randomized trial of 47 people (2006) and found no difference.

The rows run from 40 to 47 people, published from 2006 to 2016: 2 single studies.

1 no difference · 1 mixed

Grade DKnee osteoarthritis symptoms (WOMAC) · No difference
RCT · n 47 · 2006 · Adults with moderate to severe knee osteoarthritis
800 mg/day · 12 weeks
No difference from placebo in total WOMAC score, its subscales or quality of life; both groups improved on the disability subscale. Only 31 people completed the trial.
Row on the Bromelain page · PubMed 17121765 (opens PubMed)
Grade DKnee osteoarthritis symptoms versus diclofenac · Mixed
RCT · n 40 · 2016 · Adults with mild to moderate knee osteoarthritis
500 mg/day (diclofenac 100 mg/day as comparator) · 16 weeks
No difference from diclofenac at 4 weeks, and the authors called the comparison inconclusive; WOMAC scores improved from baseline after 16 weeks of bromelain (no placebo group).
Row on the Bromelain page · PubMed 27470088 (opens PubMed)