Bromelain and dental surgery
What 2 graded rows on bromelain agree on for dental surgery, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Bromelain page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Bromelain page, with its PubMed record.
Your question
Bromelain and dental surgery
2 rows · 87 peopleThey agree: both rows found an improvement.
- CGrade C× 1
- DGrade D× 1
- Rows
- 2
- Trials
- 2
- People
- 87
What the rows share
From the rowsThe best-graded row, grade C, is a randomized trial of 45 people (2014) and found an improvement.
The rows run from 42 to 45 people, published from 2014 to 2024: 2 single studies.
The rows
2 improved- CGrade CPain, swelling and quality of life after wisdom tooth removal · Improved
RCT · n 45 · 2014 · Adults having a single impacted lower wisdom tooth removed under local anesthesia
250 mg four times daily (1,000 mg/day) around surgery · 5 days (from 1 day before surgery to 4 days after)
Pain fell versus placebo at all time points and quality-of-life scores improved, similar to diclofenac; the reduction in swelling and jaw stiffness was not significant.
- DGrade DPainkiller use, pain and swelling after wisdom tooth removal · Improved
RCT · n 42 · 2024 · Adults having a single lower wisdom tooth removed under local anesthesia (Italy); three arms: pineapple extract, purified bromelain, placebo
200 mg bromelain every 6 hours for 3 days, then every 12 hours for 4 days (800 then 400 mg/day; full text) · Day of surgery plus 7 days
The placebo group needed more ibuprofen (p < 0.0001); pain and swelling fell more with both bromelain products than with placebo, and quality of life was better; trismus did not differ significantly.