Bitter Orange and weight

What 2 graded rows on bitter orange agree on for weight, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Bitter Orange page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Bitter Orange page, with its PubMed record.

Supplement

Bitter Orange Choose another

2 rows · 114 people

They agree: both rows found no difference.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade C, is a meta-analysis of 94 people (2022) and found no difference.

The rows run from 20 to 94 people, published from 2004 to 2022: 2 pooled reviews and 0 single studies.

2 no difference

Grade CBody weight and body composition · No difference
Meta-analysis · n 94 · 2022 · Adults in the weight-loss subset of placebo-controlled synephrine trials
10–54 mg/day p-synephrine · Prolonged use (weeks)
Weight loss with synephrine was not significant after prolonged treatment, and body composition did not change.
Row on the Bitter Orange page · PubMed 36235672 (opens PubMed)
Grade DWeight loss in randomized trials · No difference
Systematic review · n 20 · 2004 · Adults with overweight in the only eligible RCT
Not stated in the review abstract · 6 weeks
Only one eligible placebo-controlled trial was found, and it showed no statistically significant benefit for weight loss.
Row on the Bitter Orange page · PubMed 15541270 (opens PubMed)