Bifidobacterium longum and IBS

What 2 graded rows on bifidobacterium longum agree on for IBS, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Bifidobacterium longum page, with its PubMed record.

Your question

Supplement
Bifidobacterium longum Choose another

Bifidobacterium longum and IBS

2 rows · 664 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
Rows
2
Trials
2
People
664

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 362 people (2006) and found an improvement.

The rows run from 302 to 362 people, published from 2006 to 2017: 2 single studies.

The rows

1 improved · 1 mixed
  1. Grade CIBS symptoms (abdominal pain, bloating, bowel habit) · Improved

    RCT · n 362 · 2006 · Women with IBS of any subtype in UK primary care

    1 million, 100 million or 10 billion CFU/day vs placebo · 4 weeks

    100 million CFU was superior to placebo and to the other doses for abdominal pain, composite score, bloating, bowel dysfunction, incomplete evacuation, straining and gas; global relief exceeded placebo by more than 20% (p < 0.02). The 1 million and 10 billion CFU doses did not differ from placebo; the 10 billion CFU capsule had formulation problems.

    Row on the Bifidobacterium longum page · PubMed 16863564 (opens PubMed)

  2. Grade CAbdominal discomfort and bloating in people not under a doctor's care · Mixed

    RCT · n 302 · 2017 · US adults with abdominal discomfort and bloating at least twice a week for 3 months (275 evaluable)

    1 billion CFU/day · 4 weeks

    Symptom severity improved in both groups with no difference between probiotic and placebo (P > 0.3); the probiotic group had more bloating-free days (P < 0.05).

    Row on the Bifidobacterium longum page · PubMed 27845337 (opens PubMed)

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