Bacillus subtilis and gas and bloating
What 3 graded rows on bacillus subtilis agree on for gas and bloating, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Bacillus subtilis page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Bacillus subtilis page, with its PubMed record.
Your question
Bacillus subtilis and gas and bloating
3 rows · 276 peopleMostly no difference: 2 of 3 rows, and most of the people. 1 found an improvement.
- CGrade C× 1
- ∅No effect× 2
- Rows
- 3
- Trials
- 3
- People
- 276
Where they differ
From the rowsThe best-graded row, grade C, is a randomized trial of 76 people (2022) and found an improvement. 2 rows are graded No effect, our grade for adequately powered trials that found no effect.
By our six checks (size, design, length, who was studied, year and grade), the two sides do not differ cleanly. The dose and how each outcome was measured are in the rows below.
The rows
1 improved · 2 no difference- ∅No effectIntestinal gas symptoms in functional bloating · No difference
RCT · n 100 · 2025 · Adults with functional bloating (Rome IV)
5 billion CFU a day · 8 weeks
No difference from placebo in the global gas score or any dimension at 4 or 8 weeks; in women only, belching and flatulence eased.
Row on the Bacillus subtilis page · PubMed 39929203 (opens PubMed)
- ∅No effectBloating, abdominal discomfort and gas · No difference
RCT · n 100 · 2021 · Healthy adults with bloating
5 billion CFU a day · 4 weeks
No difference from placebo in bloating intensity, bloating days, abdominal discomfort or gas; a male subgroup improved.
Row on the Bacillus subtilis page · PubMed 31719214 (opens PubMed)
- CGrade CBloating, burping and flatulence in healthy adults · Improved
RCT · n 76 · 2022 · Healthy adults
2 billion CFU a day · 6 weeks
More people improved on the combined bloating, burping and flatulence score with BS50 than placebo (47.4% vs 22.2%; OR 3.2, p = .024); burping improved (44.7% vs 22.2%), bloating only trended (p = .071); other symptoms unchanged.
Row on the Bacillus subtilis page · PubMed 36269141 (opens PubMed)