Artichoke Extract and liver

What 2 graded rows on artichoke extract agree on for liver, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Artichoke Extract page, with its PubMed record.

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Artichoke Extract and liver

2 rows · 373 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
6
People
373
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 333 people (2022) and found an improvement.

The rows run from 40 to 333 people, published from 2022 to 2026: 1 pooled review and 1 single study.

The rows

1 improved · 1 mixed
  1. Grade CLiver enzymes and lipids in fatty liver disease · Improved

    Meta-analysis, 5 studies · n 333 · 2022 · Adults with non-alcoholic fatty liver disease in 5 RCTs

    Varied across trials · Varied across trials

    ALT and AST fell versus control (standardized mean differences about 1.0–1.1), with lower total cholesterol, LDL and triglycerides.

    Row on the Artichoke Extract page · PubMed 35763310 (opens PubMed)

  2. Grade DLiver fat and liver size in obesity before bariatric surgery · Mixed

    Pilot RCT · n 40 · 2026 · Bariatric surgery candidates with obesity and steatotic liver disease (MASLD)

    Not stated in the abstract · 6 weeks

    Liver fat (FibroScan CAP) and liver lobe diameters fell versus placebo, with improvement already seen at 3 weeks, and fat-mass percentage fell. Transaminases rose in the extract group, particularly AST; total and LDL cholesterol improved in female participants.

    Row on the Artichoke Extract page · PubMed 41274796 (opens PubMed)

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